1) The development of methods for the instrumental evaluation of physical activity programs aimed mainly at subjects suffering from dysmetabolic disorders.
2) The application of the phosphorus Magnetic Resonance Spectroscopy of (31P MRS) of skeletal muscle to the study of energy metabolism both in healthy subjects and in patients with genetically based enzymatic deficits.
3) The application of advanced Magnetic Resonance Imaging (MRI) techniques of the brain and muscle for the characterization of physiological variability (due to aging, sex, and other factors) and for the identification of diagnostic and prognostic MRI markers early, surrogate therapy efficacy and disease pathogenetic mechanisms in neurodegenerative and dysmetabolic disorders.
