Keywords:
hypercoagulability
thrombophilia
oral anticoagulants
heparin
venous thromboembolism
pulmonary embolism
coagulopathies
peripheral arterial disease
deep vein thrombosis
The main interest are the pathogenesis, diagnosis and treatment of
venous thromboembolism ( deep vein thrombosis and pulmonary
embolism).
The main research areasa are the following:
- the optimal duration of treatment with vitamin K antagonists
(VKAs) after a first episode of unprovoked venous thromboembolism
(VTE).The risk of recurrence after VKA withdrawal differs
individually and markers of individual risk prediction could help
tailor VKA duration. In addition to the characteristics of
the index event, several factors have emerged as predictors of risk
for recurrence after VKA withdrawal, such as D-dimer (D-d),
residual venous obstruction, thrombophilia and factor VIII. We have
shown how D-dimero if altered after the withdrawal of vitamin K
antagonists is a risk factor for recurrence both in cohort and
multicentre clinical trials.
2- diagnosis of distal DVT
3 - follow-up of pulmonary embolism
