Foto del docente

Benilde Cosmi

Associate Professor

Department of Medical and Surgical Sciences

Academic discipline: MED/11 Cardiovascular Diseases


Keywords: hypercoagulability thrombophilia oral anticoagulants heparin venous thromboembolism pulmonary embolism coagulopathies peripheral arterial disease deep vein thrombosis

The main interest are the pathogenesis, diagnosis and treatment of venous thromboembolism ( deep vein thrombosis and pulmonary embolism).
The main research areasa are the following:
- the optimal duration of treatment with vitamin K antagonists (VKAs) after a first episode of unprovoked venous thromboembolism (VTE).The risk of recurrence after VKA withdrawal differs individually and markers of individual risk prediction could help tailor VKA duration. In addition to the characteristics of the index event, several factors have emerged as predictors of risk for recurrence after VKA withdrawal, such as D-dimer (D-d), residual venous obstruction, thrombophilia and factor VIII. We have shown how D-dimero if altered after the withdrawal of vitamin K antagonists is a risk factor for recurrence both in cohort and multicentre clinical trials.
2- diagnosis of distal DVT
3 - follow-up of pulmonary embolism

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