NUTRITION AND AGING:
- • Diet, inflammation and aging
- Diet, inflammation and metabolic risk
- • Nutritional needs and diets suitable for over 65s
- • Mediterranean diet and aging
- • Measurement of pro and anti-inflammatory cytokines
- • Genetic and epigenetic factors related to nutrition
- • Study of intestinal microbiota changes with diet
- • Measurement of body composition and changes associated with diet and inflammatory status
MITOCHONDRIAL DNA IN AGING AND AGE RELATED DISEASES:
- Circulating mtDNA as biomarker
- mtDNA rearrangements in human tissues at different age
- mtDNA mutations in human aging
- Association of mtDNA haplogroups and subhaplogroups with Alzheimer’s Disease.
- Accumulation of mtDNA somatic mutations in Alzheimer’s disease affected brains: studies on mtDNA complete sequences.
PROTEASOME AND IMMUNOPROTEASOME IN AGING AND AGE RELATED DISEASES:
Immunoproteasomes in antigen presentation and protein degradation:
- Immunoproteasomes genetic variants involved in the Multiple Sclerosis onset and their immunological mechanism (alterations of MHC class I restricted antigen presentation).
- Expression, activity and cellular localization of Immunoproteasome in Alzheimer’s Disease affected brains.
- Effect of Epstein Barr Virus on aging and immunoproteasomes features: Studies on Lymphoblastoid Cell Lines.
