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Andrea Milelli

Professore associato

Dipartimento di Scienze per la Qualità della Vita

Settore scientifico disciplinare: CHIM/08 CHIMICA FARMACEUTICA

Pubblicazioni

De Simone A, La Pietra V, Betari N, Petragnani N, Conte M, Daniele S, Pietrobono D, Martini C, Petralla S, Casadei R, Davani L, Frabetti F, Russomanno P, Novellino E, Montanari S, Tumiatti V, Ballerini P, Sarno F, Nebbioso A, Altucci L, Monti B, Andrisano V, Milelli A., Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease., «ACS MEDICINAL CHEMISTRY LETTERS», 2019, 10, pp. 469 - 474 [articolo]

Recagni M.; Greco M.L.; Milelli A.; Minarini A.; Zaffaroni N.; Folini M.; Sissi C., Distinct biological responses of metastatic castration resistant prostate cancer cells upon exposure to G-quadruplex interacting naphthalenediimide derivatives, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2019, 177, pp. 401 - 413 [articolo]

Di Paolo, Maria Luisa; Cervelli, Manuela; Mariottini, Paolo; Leonetti, Alessia; Polticelli, Fabio; Rosini, Michela; Milelli, Andrea; Basagni, Filippo; Venerando, Rina; Agostinelli, Enzo; Minarini, Anna, Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase, «JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY», 2019, 34, pp. 740 - 752 [articolo]

De Simone Angela; Milelli Andrea, Histone Deacetylase Inhibitors as Multitarget Ligands: New Players in Alzheimer's Disease Drug Discovery?, «CHEMMEDCHEM», 2019, 14, pp. 1067 - 1073 [articolo]

Manuela, Basso; Huan Huan Chen, ; Debasmita, Tripathy; Mariarosaria, Conte; Apperley, Kim Y. P.; DE SIMONE, Angela; Keillor, Jeffrey W.; Rajiv, Ratan; Angela, Nebbioso; Federica, Sarno; Lucia, Altucci; Milelli, Andrea, Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death, «CHEMMEDCHEM», 2018, 13, pp. 227 - 230 [articolo]

Milelli, Andrea; Marchetti, Chiara; Turrini, Eleonora; Catanzaro, Elena; Mazzone, Roberta; Tomaselli, Daniela; Fimognari, Carmela; Tumiatti, Vincenzo; Minarini, Anna, Novel polyamine-based Histone deacetylases-Lysine demethylase 1 dual binding inhibitors, «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2018, 28, pp. 1001 - 1004 [articolo]

DE SIMONE, Angela; Fiori, Jessica; Naldi, Marina; D'Urzo, Annalisa; Tumiatti, Vincenzo; Milelli, Andrea; Andrisano, Vincenza, Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors, «JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS», 2017, 144, pp. 159 - 166 [articolo]

De Simone, Angela; Bartolini, Manuela; Baschieri, Andrea; Apperley, Kim Y.P.; Chen, Huan Huan; Guardigni, Melissa; Montanari, Serena; Kobrlova, Tereza; Soukup, Ondrej; Valgimigli, Luca; Andrisano, Vincenza; Keillor, Jeffrey W.; Basso, Manuela; Milelli, Andrea, Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2017, 139, pp. 378 - 389 [articolo]

Milelli, Andrea; Marchetti, Chiara; Greco, Maria Laura; Moraca, Federica; Costa, Giosuè; Turrini, Eleonora; Catanzaro, Elena; Betari, Nibal; Calcabrini, Cinzia; Sissi, Claudia; Alcaro, Stefano; Fimognari, Carmela; Tumiatti, Vincenzo; Minarini, Anna, Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2017, 128, pp. 107 - 122 [articolo]

Alice, Pasini; Chiara, Marchetti; Claudia, Sissi; Marilisa, Cortesi; Emanuele, Giordano; Anna, Minarini; Andrea, Milelli, Novel Polyamine–Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming, «ACS MEDICINAL CHEMISTRY LETTERS», 2017, 8, pp. 1218 - 1223 [articolo]

Milelli, Andrea; De Simone, Angela; Ticchi, Nicole; Chen, Huan Huan; Betari, Nibal; Andrisano, Vincenza; Tumiatti, Vincenzo, Tacrine-based Multifunctional Agents in Alzheimer's Disease: an Old Story in Continuous Development, «CURRENT MEDICINAL CHEMISTRY», 2017, 24, pp. 1 - 1 [articolo]

Tarozzi, A; Marchetti, C; Nicolini, B; D'Amico, M; Ticchi, N; Pruccoli, L; Tumiatti, V; Simoni, E; Lodola, A; Mor, M; Milelli, A; Minarini, A., Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate., «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2016, 117, pp. 283 - 291 [articolo]

D'Urzo, Annalisa; DE SIMONE, Angela; Fiori, Jessica; Naldi, Marina; Milelli, Andrea; Andrisano, Vincenza, Direct determination of GSK-3β activity and inhibition by UHPLC-UV-vis diode arrays detector (DAD), «JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS», 2016, 124, pp. 104 - 111 [articolo]

Milelli, Andrea; Turrini, Eleonora; Catanzaro, Elena; Maffei, Francesca; Fimognari, Carmela, Perspectives in Designing Multifunctional Molecules in Antipsychotic Drug Discovery, «DRUG DEVELOPMENT RESEARCH», 2016, 77, pp. 437 - 443 [articolo]

Tumiatti, Vincenzo; Milelli, Andrea, Farmaci Tiroidei, in: Chimica farmaceutica, Rozzano (MI), Casa Editrice Ambrosiana, 2015, pp. 583 - 594 [capitolo di libro]