1) MOLECULAR BIOTECHNOLOGY OF PHAGES
Phage biotechnologies represent an emerging approach for the development of innovative nanomedicines and biosensors. Our activity in this field pertains the implementation of synthetic & chemical biology as well as advanced molecular techniques for the exploitation of filamentous phages as a versatile targeting vector against a microbial pathogens and tumors.
2) MOLECULAR MICROBIOLOGY AND METALLO-REGULATION IN HELICOBACTER PYLORI
We are interested in fundamental molecular aspects that regulate the expression of genes
and virulence factors in microorganisms. We use the human gastric pathogen Helicobacter pylori as model
system to study gene regulation of infectious agents that have the
ability to persist as obligate, life-lasting pathogens.
Main research themes focus on metal sensing and stress response.
These topics have a wide interest because regulation of metal
homeostasis and stress responses is paramount to all organisms, and
especially important in triggering the expression of virulence
factors in many pathogens.