Foto del docente

Alberto Danielli

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/11 Molecular Biology

Research

Keywords: Phage Molecular Microbiology Helicobacter pylori Nanobiotechnology theranostic vector

1) MOLECULAR BIOTECHNOLOGY OF PHAGES

Phage biotechnologies represent an emerging approach for the development of innovative nanomedicines and biosensors. Our activity in this field pertains the implementation of synthetic & chemical biology as well as advanced molecular techniques for the exploitation of filamentous phages as a versatile targeting vector against a microbial pathogens and tumors.

 

2) MOLECULAR MICROBIOLOGY AND METALLO-REGULATION IN HELICOBACTER PYLORI

We are interested in fundamental molecular aspects that regulate the expression of genes and virulence factors in microorganisms. We use the human gastric pathogen Helicobacter pylori as model system to study gene regulation of infectious agents that have the ability to persist as obligate, life-lasting pathogens.

Main research themes focus on metal sensing and stress response. These topics have a wide interest because regulation of metal homeostasis and stress responses is paramount to all organisms, and especially important in triggering the expression of virulence factors in many pathogens.




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