Foto del docente

Roberto Tonelli

Assistant professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/14 Pharmacology

Publications

Raieli S.; Di Renzo D.; Lampis S.; Amadesi C.; Montemurro L.; Pession A.; Hrelia P.; Fischer M.; Tonelli R., MYCN Drives a Tumor Immunosuppressive Environment Which Impacts Survival in Neuroblastoma, «FRONTIERS IN ONCOLOGY», 2021, 11, pp. 625207 - 625218 [Scientific article]

Moreno L.; Barone G.; DuBois S.G.; Molenaar J.; Fischer M.; Schulte J.; Eggert A.; Schleiermacher G.; Speleman F.; Chesler L.; Geoerger B.; Hogarty M.D.; Irwin M.S.; Bird N.; Blanchard G.B.; Buckland S.; Caron H.; Davis S.; De Wilde B.; Deubzer H.E.; Dolman E.; Eilers M.; George R.E.; George S.; Jaroslav; Maris J.M.; Marshall L.; Merchant M.; Mortimer P.; Owens C.; Philpott A.; Poon E.; Shay J.W.; Tonelli R.; Valteau-Couanet D.; Vassal G.; Park J.R.; Pearson A.D.J., Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma, «EUROPEAN JOURNAL OF CANCER», 2020, 136, pp. 52 - 68 [Scientific article]

Montemurro L.; Raieli S.; Angelucci S.; Bartolucci D.; Amadesi C.; Lampis S.; Scardovi A.L.; Venturelli L.; Nieddu G.; Cerisoli L.; Fischer M.; Teti G.; Falconi M.; Pession A.; Hrelia P.; Tonelli R., A novel MYCN-specific antigene oligonucleotide deregulates mitochondria and inhibits tumor growth in MYCN-amplified neuroblastoma, «CANCER RESEARCH», 2019, 79, pp. 6166 - 6177 [Scientific article]Open Access

A. Astolfi; F. Vendemini; M. Urbini; F. Melchionda; R. Masetti; M. Franzoni; V. Libri; S. Serravalle; M. Togni; L. Montemurro; R. Rondelli; G. Paone; D. Bressanin; F. Chiarini; A.M. Martelli; R. Tonelli; A. Pession., MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia, «ONCOTARGET», 2014, 5, pp. 120 - 130 [Scientific article]

Bergantin E; Quarta C; Nanni C; Fanti S; Pession A; Cantelli-Forti G; Tonelli R; Hrelia P, Sulforaphane induces apoptosis in rhabdomyosarcoma and restores TRAIL-sensitivity in the aggressive alveolar subtype leading to tumor elimination in mice., «CANCER BIOLOGY & THERAPY», 2014, 15, pp. 1219 - 1225 [Scientific article]

Carmelo Quarta; Erika Cantelli; Cristina Nanni; Valentina Ambrosini; Daniela D’ambrosio; Korinne Di Leo; Silvia Angelucci; Federico Zagni; Filippo Lodi; Mario Marengo; William A. Weiss; Andrea Pession; Roberto Tonelli; Stefano Fanti, Molecular Imaging of Neuroblastoma Progression in TH-MYCN Transgenic Mice, «MOLECULAR IMAGING AND BIOLOGY», 2013, 15(2), pp. 194 - 202 [Scientific article]

R. Tonelli; A. McIntyre; C. Camerin; Z.S. Walters; K. Di Leo; J. Selfe; S. Purgato; E. Missiaglia; A. Tortori; J. Renshaw; A. Astolfi; K.R. Taylor; S. Serravalle; R. Bishop; C. Nanni; L.J. Valentijn; A. Faccini; I. Leuschner; S. Formica; Jorge S Reis-Filho9; V. Ambrosini; K. Thway; M. Franzoni; B. Summersgill; R. Marchelli; P. Hrelia; G. Cantelli-Forti; S. Fanti; R. Corradini; A. Pession; J. Shipley, Antitumor Activity of Sustained N-Myc Reduction in Rhabdomyosarcomas and Transcriptional Block by Antigene Therapy, «CLINICAL CANCER RESEARCH», 2012, 18, pp. 796 - 807 [Scientific article]

D MONTAGNA; I TURIN; R SCHIAVO; E MONTINI; N ZAFFARONI; R VILLA; S SECONDINO; I SCHIAVETTO; L CALIOGNA; F LOCATELLI; VIRGINIA LIBRI; ANDREA PESSION; R TONELLI; R MACCARIO; S SIENA; P PEDRAZZOLI, Feasibility and safety of adoptive immunotherapy with ex vivogenerated autologous, cytotoxic T lymphocytes in patients with solid tumor, «CYTOTHERAPY», 2012, 14, pp. 80 - 90 [Scientific article]

FAZZINA R.; LOMBARDINI L.; MEZZANOTTE L.; RODA A.; HRELIA P; PESSION A.; TONELLI R., Generation and characterization of bioluminescent xenograft mouse models of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting siRNA nanoparticles, «INTERNATIONAL JOURNAL OF ONCOLOGY», 2012, 41, pp. 621 - 628 [Scientific article]

M. Dekker; S. de Vries; M. Aarts; R. Dekker; C Brouwersa; O. Wiebenga; N. de Wind; E. Cantelli; R. Tonelli; H te Riele, Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides, «MUTATION RESEARCH», 2011, 715, pp. 52 - 60 [Scientific article]

Sforza S.; Tedeschi T.; Calabretta A.; Corradini R.; Camerin C.; Tonelli R.; Pession A.; Marchelli R., A Peptide Nucleic Acid Embedding a Pseudopeptide Nuclear Localization Sequence in the Backbone Behaves as a Peptide Mimic, «EUROPEAN JOURNAL OF ORGANIC CHEMISTRY», 2010, 13, pp. 2441 - 2444 [Scientific article]

R. Tonelli; B. Luppi; L. Lombardini; S. Rampelli; P. Hrelia; A. Pession, Chitosan nanoparticles for siRNA delivery: influence of nanoparticle composition on gene silencing efficiency, in: THIRD BIOTECH WORKSHOP, "Drug delivery systems for biotech products", PAVIA, s.n, 2010, pp. 22 - 22 (atti di: THIRD BIOTECH WORKSHOP, "Drug delivery systems for biotech products", Pavia, March 24-25th) [Abstract]

Mezzanotte L; Fazzina R; Michelini E; Tonelli R; Pession A; Branchini B; Roda A, In vivo bioluminescence imaging of murine xenograft cancer models with a red-shifted thermostable luciferase., «MOLECULAR IMAGING AND BIOLOGY», 2010, 12, pp. 406 - 414 [Scientific article]

V MARTINO; A BIANCHERA; L REIA; O BUSSOLATI; R FAZZINA; F MARINO; L MONTEMURRO; R TONELLI; A PESSION; GC GAZZOLA; R SALA, Down-regulation of HOXA4, HOXA7, HOXA10, HOXA11 and MEIS1 during monocyte-macrophage differentiation in THP-1 cells, «MOLECULAR MEDICINE REPORTS», 2009, 2, pp. 241 - 244 [Scientific article]

Faccini A; Tortori A; Tedeschi T; Sforza S; Tonelli R; Pession A; Corradini R; Marchelli R., Circular dichroism study of DNA binding by a potential anticancer peptide nucleic acid targeted against the MYCN oncogene., «CHIRALITY», 2008, 20, pp. 494 - 500 [Scientific article]

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