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Paola Dal Monte

Assistant professor

Department of Experimental, Diagnostic and Specialty Medicine - DIMES

Academic discipline: MED/07 Microbiology and Clinical Microbiology

Curriculum vitae

Download Curriculum Vitae (.doc 348KB )

Researcher at the University of Bologna since 1998, she carries out her research in the field of clinical microbiology, at S. Orsola-Malpighi University Hospital. Her research interests are in the area of mycobacterial infections, in particular those supported by Mycobacterium tuberculosis. Currently she has been focused on the development of molecular and immunological techniques for the diagnosis of infection.


EDUCATION

1989: Graduated in Biological Science "cum laude" at the University of Bologna, Italy,under the direction of Prof. M. La Placa. Dissertation topic: Identification and diagnostic use of recombinant proteins of Human Cytomegalovirus.

1989-1990:  Stage of one year at the Codivilla Putti Research Institut , in the Laboratory of Genetic and Immunology Bologna , Italy directed by Prof. A. Facchini.

1992-1995: Post-Doctoral fellow at the Pasteur Institut, Paris, France in the Laboratory of Immunology and Virology directed by Prof. J.L. Virilizier, supervised by Dott. S. Michelson.

1995: Specialization Degree in Microbiology and Virology "cum laude" at the University of Bologna, Italy, under the direction of Prof. M.P. Landini Dissertation topic: Cloning of human cytomegalovirus (HCMV) UL83 and study of the function of its product.

PRESENT POSITION

Since 1998: Assistant Professor in Microbiology and Clinical Microbiology (MED/07), Faculty of Medicine,  University of Bologna, Italy.

Since 1999: Biologist of the Service of Microbiology and Virology, S. Orsola General Hospital, Bologna taly

Fellowships and Awards: Italian Ministry of Health (1992-1994), CIB (1995); First Prize funded by ABT (Advanced BioTechnology): VI European Edition of the OAK-RIDGE conference on advanced technology for the clinical laboratory and biotechnology (1990).

Fundings obtained: As partecipant: since 1991: AIDS prjects, Istituto Superiore di Sanità; BIOMED II, CEE; MURST (ex 40%), University of Bologna (ex 60%). As leader: Progetto Giovani RicercatoriUniversity of Bologna (1999);  progetto di Ricerca Fondamentale Orientata (RFO - ex 60%) since 2002

SCIENTIFIC ACTIVITY

1989-90: at the Research Institut Codivilla Putti, Bologna, in the Laboratory of Genetic and Immunology.

Main topics:

-          Humoral response anti-HBs following vaccination with cDNA HBsAg.

-          Evaluation of intracellular nucleotides in lymphocytes and granulocytes from normal ageing subjects.

1990: First prize at the "ATB'90, IV European Edition of the OAK RIDGE conference on advanced Technology for the Clinical laboratory and Biotechnology" with the subject:

-          "Human cytomegalovirus recombinant antigens: production, characterization and use as a diagnostic tool."

1990-92: at the Institut of Microbiology of Bologna.  Main topics:

-          Study of the humoral response against sintetic peptides of structural and non structural antigens of Human Cytomegalovirus

-          Study of the correlation between virus detection and serology for the diagnosis of active Cytomegalovirus infection in AIDS patients.

1992-95: at the Pasteur Institut, Paris, France in the Laboratory of Immunology and Virology:

Grants:  from the Italian Institut of Health, AIDS project  and from the European Community, Biomed projecrt

Main topics:  Study of the role of Human Cytomegalovirus structural antigens in the initiation of viral replicative cycle and regulation of the host cell metabolism in relation to HIV-1.

Modulation of chemochines production during HCMV infection

 

Up today: at the Department of Clinical and Experimental Medicine, Division of Microbiology,University of Bologna, Italy.  Main topics:

-  Expression and characterization of HCMV UL83, UL53 and UL73 gene products

- Study of gpUL73 (gN)polymorphisms and use of gN as possible virulence markers of clinical HCMV isolates

- Sepsis in immunocompromised patients

- Mycobacterium tuberculosis infection in children and in immunocompromised patients

 

 

 

 



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