Cancers of Unknown Primary: Molecular characterization with microRNA signatures. Development of patient-derived in vitro and in vivo models. Genetic characterization. Cancer-specific treatments.
Molecular characterization of microRNA alterations in melanoma subtypes and prognostic groups.
Absolute quantification of circulating microRNAs in biological fluids and extracellular vescicles with droplet digital PCR.
Patent: https://www.unibo.it/it/terza-missione/universita-e-impresa/brevetti-ateneo/brevetti-ateneo/scheda/253
Functional analysis of microRNA isoforms.
Development of NGS panels for target sequencing. SmallRNA sequencing. Single-cell sequencing.
Isolation of circulating tumor cells from metastatic tumors with gnostic and agnostic systems. Their characterization and cell-line establishment.
Identification of biomarkers of response to CAR-T cell therapy.
