Cancers of Unknown Primary: Molecular characterization with microRNA signatures. Development of patient-derived in vitro and in vivo models. Genetic characterization. Cancer-specific treatments.
Molecular characterization of microRNA alterations in melanoma subtypes and prognostic groups.
Patent: https://www.unibo.it/it/terza-missione/universita-e-impresa/brevetti-ateneo/brevetti-ateneo/scheda/253
Absolute quantification of circulating microRNAs in biological fluids and extracellular vescicles with droplet digital PCR.
Functional analysis of microRNA isoforms.
Development of NGS panels for target sequencing. SmallRNA sequencing. Single-cell sequencing.
Isolation of circulating tumor cells from metastatic tumors with gnostic and agnostic systems. Their characterization and cell-line establishment.
Identification of biomarkers of response to CAR-T cell therapy.
https://dimes.unibo.it/it/ricerca/gruppi-di-ricerca/non-coding-rnas-and-cancer-biomarkers
