Professional profile
I currently hold the position of PhD student in Biomedical and Neuromotor Sciences at DIBINEM (University of Bologna) and I’m part of the Neurogenetic program at IRCCS Istituto delle Scienze Neurologiche di Bologna, Bellaria Hospital. Here I study 2D and 3D neuronal cellular models for the in vitro evaluation of novel therapies for rare neurogenetic diseases, in particular mitochondrial diseases.
Core skills
- 2D cell cultures (iPSCs, lines and primary cells)
- 3D cell models (organoids)
- Digital droplet PCR
- Real time PCR
- Western blot
- Seahorse assay
- Immunofluorescence
- Confocal microscopy
- Electroporation
- CRISPR Cas9
- Calcium imaging
- English language C1
- Office suite
- GraphPad Prism
Working experience
- PhD STUDENT in Biomedical and Neuromotor Sciences at DIBINEM (University of Bologna) and IRCCS Istituto delle Scienze Neurologiche di Bologna; November 2024 – present
- BIOTECHNOLOGIST FELLOW; October 2022 – October 2024; IRCCS Istituto delle Scienze Neurologiche di Bologna, Bellaria Hospital, AUSL Bologna
Publications
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Abstract for the national meeting Mitoconference 2024 “Generation and characterization of patient-derived induced pluripotent stem cells and neuronal progenitors carrying the m.8344A>G at high heteroplasmy”, Giulia Sacchetti, Giada Capirossi, Mariantonietta Capristo, Valentina Del Dotto, Claudio Fiorini, Leonardo Caporali, Chiara La Morgia, Annalinda Pisano, Carla Giordano, Giulia D’Amati, Stephanie Le, Alessandro Prigione, Valerio Carelli, Alessandra Maresca
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Abstract for the national RIN network conference 2023 (Rome) “Establishing disease-relevant models to challenge MERRF: an approach to unveil new therapeutic strategies in patient-derived neural progenitors and cortical organoids”, Giada Capirossi, Valentina Del Dotto, Mariantonietta Capristo, Giulia Sacchetti, Claudio Fiorini, Leonardo Caporali, Chiara La Morgia, Annalinda Pisano, Carla Giordano, Giulia d’Amati, Stephanie Le, Alessandro Prigione, Alessandra Maresca, Valerio Carelli
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Abstract for the international meeting Euromit2023 “In vitro 2D and 3D neuronal models generation of MERRF disease to test therapeutic strategies”, Giada Capirossi, Valentina Del Dotto, Mariantonietta Capristo, Giulia Sacchetti, Claudio Fiorini, Annalinda Pisano, Carla Giordano, Giulia d’Amati, Alessandro Prigione, Alessandra Maresca, Valerio Carelli
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Abstract for the XXI Scientific Convention Telethon 2023 “Cure MERRF: from fibroblasts to organoids speeding basic science into clinical trials for mitochondrial diseases”, Alessandra Maresca, Giada Capirossi, Mariantonietta Capristo, Valentina Del Dotto, Giulia Sacchetti, Concetta Valentina Tropeano, Annalinda Pisano, Carla Giordano, Giulia d’Amati, Valerio Carelli
Congresses and conferences
- Workshop “Cracking the elusive relationship between the fusion protein OPA1, mitochondrial membrane lipid composition and maintenance of membrane-anchored mtDNA nucleoids” (December 2024)
- Mitoconference 2024 (October 2024)
- Conference “Microbioma e la salute dell’uomo, degli organismi viventi e del Pianeta” (November 2023)
- Euromit2023 - International meeting on mitochondrial pathology (June 2023)
- XXI Scientific Convention Telethon (March 2023)
Education and training
- Professional qualification to practice as a Biologist - section A; May 2023
- Master’s degree in Pharmaceutical Biotechnology - mark 110 L; October 2019 - March 2022; Alma Mater Studiorum - University of Bologna School of Pharmacy, Biotechnology and Motor Sciences; LM-9 - 2nd level degree in medical, veterinary and pharmaceutical biotechnologies; QEQ 7 level
- Bachelor’s degree in Biotechnologies; October 2016 - October 2019; Alma Mater Studiorum - University of Bologna School of Pharmacy, Biotechnology and Motor Sciences; L-2 - 1st level degree in Biotechnologies; QEQ 6 level
