Foto del docente

Giovanni Capranico

Full Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/11 Molecular Biology

Publications

Coordination of a Research Project: Mechanistic roles of R-loops and micronuclei in the innate immune response induced by anticancer G-quadruplex binders.

Marzano S.; Miglietta G.; Morigi R.; Marinello J.; Arleo A.; Procacci M.; Locatelli A.; Leoni A.; Pagano B.; Randazzo A.; Amato J.; Capranico G., Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 12055 - 12067 [Scientific article]

Miglietta G.; Marinello J.; Russo M.; Capranico G., Ligands stimulating antitumour immunity as the next G-quadruplex challenge, «MOLECULAR CANCER», 2022, 21, pp. 180 - 194 [Scientific article]

Jessica Marinello, Andrea Arleo, Marco Russo, Maria Delcuratolo, Francesca Ciccarelli, Yves Pommier, Giovanni Capranico., Topoisomerase I poison-triggered immune gene activation is markedly reduced in human small-cell lung cancers by impairment of the cGAS/STING pathway, «BRITISH JOURNAL OF CANCER», 2022, 127, pp. 1214 - 1225 [Scientific article]

Capranico, G.; Martegani, E.; Musci, G.; Raugei, G.; Russo, T.; Zambrano, N.; Zappavigna, V., Biologia molecolare. Con ebook. Con software di simulazione, Napoli, Edises Università srl, 2021, pp. 604 . [Research monograph]

Miglietta G.; Russo M.; Duardo R.C.; Capranico G., G-quadruplex binders as cytostatic modulators of innate immune genes in cancer cells, «NUCLEIC ACIDS RESEARCH», 2021, 49, pp. 6673 - 6686 [Scientific article]Open Access

Maurizio Balistreri; Giovanni Capranico; Matteo Galletti; Silvia Zullo, Biotecnologie e modificazioni genetiche. Scienza, etica, diritto, Bologna, il Mulino, 2020, pp. 190 . [Research monograph]

Giulia Miglietta; Marco Russo; Giovanni Capranico, G-quadruplex–R-loop interactions and the mechanism of anticancer G-quadruplex binders, «NUCLEIC ACIDS RESEARCH», 2020, 48, pp. 11942 - 11957 [Scientific article]Open Access

Amato J.; Miglietta G.; Morigi R.; Iaccarino N.; Locatelli A.; Leoni A.; Novellino E.; Pagano B.; Capranico G.; Randazzo A., Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells, «JOURNAL OF MEDICINAL CHEMISTRY», 2020, 63, pp. 3090 - 3103 [Scientific article]

De Magis, Alessio; Manzo, Stefano G.; Russo, Marco; Marinello, Jessica; Morigi, Rita; Sordet, Olivier; Capranico, Giovanni*, DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells, «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 2019, 116, pp. 816 - 825 [Scientific article]

Russo M.; De Lucca B.; Flati T.; Gioiosa S.; Chillemi G.; Capranico G., DROPA: DRIP-seq optimized peak annotator, «BMC BIOINFORMATICS», 2019, 20, Article number: 414 , pp. 414 - 420 [Scientific article]Open Access

Cristini A.; Ricci G.; Britton S.; Salimbeni S.; Huang S.-Y.N.; Marinello J.; Calsou P.; Pommier Y.; Favre G.; Capranico G.; Gromak N.; Sordet O., Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks, «CELL REPORTS», 2019, 28, pp. 3167 - 3181 [Scientific article]Open Access

Marinello, Jessica; Delcuratolo, Maria; Capranico, Giovanni, Anthracyclines as Topoisomerase II Poisons: From Early Studies to New Perspectives, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2018, 19, Article number: 3480 , pp. 1 - 18 [Scientific article]Open Access

Manzo, Stefano G.; Hartono, Stella R.; Sanz, Lionel A.; Marinello, Jessica; De Biasi, Sara; Cossarizza, Andrea; Capranico, Giovanni*; Chedin, Frederic, DNA Topoisomerase I differentially modulates R-loops across the human genome, «GENOME BIOLOGY», 2018, 19, Article number: 100 , pp. 1 - 18 [Scientific article]Open Access

Alessio De Magis, Stefano G. Manzo, Jessica Marinello, Marco Russo, Olivier Sordet, Rita Morigi, Giovanni Capranico, Genome instability by G-quadruplex ligands are mediated by R-loops in human cancer cells, in: BIONIC 2018 - Biology of non-canonical nucleic acids: from humans to pathogens - International Symposium - Abstract Book, 2018, pp. 24 - 24 (atti di: BIONIC 2018 - Biology of non-canonical nucleic acids: from humans to pathogens - International Symposium, Padova, 26-28 settembre 2018) [Abstract]

Latest news

At the moment no news are available.