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Giovanni Capranico

Professore ordinario

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: BIO/11 BIOLOGIA MOLECOLARE

Coordinatore del Corso di Dottorato in Biologia cellulare e molecolare

Pubblicazioni

De Magis, Alessio; Manzo, Stefano G.; Russo, Marco; Marinello, Jessica; Morigi, Rita; Sordet, Olivier; Capranico, Giovanni*, DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells, «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 2019, 116, pp. 816 - 825 [articolo]

Marinello, Jessica; Delcuratolo, Maria; Capranico, Giovanni, Anthracyclines as Topoisomerase II Poisons: From Early Studies to New Perspectives, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2018, 19, pp. 1 - 18 [articolo]

Manzo, Stefano G.; Hartono, Stella R.; Sanz, Lionel A.; Marinello, Jessica; De Biasi, Sara; Cossarizza, Andrea; Capranico, Giovanni*; Chedin, Frederic, DNA Topoisomerase I differentially modulates R-loops across the human genome, «GENOME BIOLOGY», 2018, 19, pp. 1 - 18 [articolo]

Alessio De Magis, Stefano G. Manzo, Jessica Marinello, Marco Russo, Olivier Sordet, Rita Morigi, Giovanni Capranico, Genome instability by G-quadruplex ligands are mediated by R-loops in human cancer cells, in: BIONIC 2018 - Biology of non-canonical nucleic acids: from humans to pathogens - International Symposium - Abstract Book, 2018, pp. 24 - 24 (atti di: BIONIC 2018 - Biology of non-canonical nucleic acids: from humans to pathogens - International Symposium, Padova, 26-28 settembre 2018) [atti di convegno-abstract]

Baranello, Laura; Kouzine, Fedor; Wojtowicz, Damian; Cui, Kairong; Zhao, Keji; Przytycka, Teresa M.; Capranico, Giovanni; Levens, David, Mapping DNA breaks by next-generation sequencing, in: Methods in Molecular Biology: Genome Instability, New York, NY, Humana Press Inc., 2018, pp. 155 - 166 [capitolo di libro]

A. De Magis, S. G. Manzo, M. Russo, J. Marinello, O. Sordet, R. Morigi, G. Capranico., R loop-driven genome instability by G-quadruplex binders in BRCA2-silenced human cancer cells., in: AACR Annual Meeting 2018. Chicago, April 14 - 18, 2018. Abstract Book, 2018, pp. 4838 - 4838 (atti di: AACR Annual Meeting 2018., Chicago, USA, April 14 - 18, 2018) [atti di convegno-poster]

R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, J. Marinello, G. Capranico, E. Novellino, A. Randazzo, Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents, in: BIONIC 2018: Biology of non-canonical nucleic acids: from humans to pathogens. 26th - 28th September 2018 - Padova, Italy - Abstract Book, Padova, 2018, pp. 126 - 126 (atti di: BIONIC 2018: Biology of non-canonical nucleic acids: from humans to pathogens., Padova, 26-28 settembre 2018) [atti di convegno-abstract]

Amato, Jussara; Pagano, Alessia; Cosconati, Sandro; Amendola, Giorgio; Fotticchia, Iolanda; Iaccarino, Nunzia; Marinello, Jessica; De Magis, Alessio; Capranico, Giovanni; Novellino, Ettore; Pagano, Bruno; Randazzo, Antonio, Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: A new opportunity in the targeting of G-rich DNA structures?, «BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS», 2017, Volume 1861, pp. 1271 - 1280 [articolo]

A. De Magis, S. G. Manzo, J. Marinello, R. Morigi, M. Rambaldi, O. Sodet, G. Capranico., G-quadruplex binders cause DNA damage by inducing R loops in human cancer cells., in: 6th International Meeting on Quadruplex Nuceic Acids: G4thering. Prague, May 31st-June 3rd, 2017 - Abstract Book, 2017, pp. 221 - 221 (atti di: 6th International Meeting on Quadruplex Nuceic Acids: G4thering., Praga, Repubblica Ceca, 31 maggio - 03 giugno 2017) [atti di convegno-abstract]

Miglietta, Giulia; Cogoi, Susanna; Marinello, Jessica; Capranico, Giovanni; Tikhomirov, Alexander S.; Shchekotikhin, Andrey; Xodo, Luigi E., RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation, «JOURNAL OF MEDICINAL CHEMISTRY», 2017, 60, pp. 9448 - 9461 [articolo]

Beretta, Giovanni L.; Ribaudo, Giovanni; Menegazzo, Ileana; Supino, Rosanna; Capranico, Giovanni; Zunino, Franco; Zagotto, Giuseppe, Synthesis and Evaluation of New Naphthalene and Naphthoquinone Derivatives as Anticancer Agents, «ARCHIV DER PHARMAZIE», 2017, 350, pp. xx - xx [articolo]

N. Iaccarino, J. Amato, R. Morigi, A. Pagano, A. De Magis, G. Capranico, A. Locatelli, A. Graziadio, A. Leoni, M. Rambaldi, E. Novellino, S. Neidle, B. Pagano, A. Randazzo., Toward the development of specific G-quadruplex binders: biophysical studies of new hydrazone derivatives., in: 6th International Meeting on Quadruplex Nuceic Acids: G4thering. Prague, May 31st-June 3rd, 2017 - Abstract Book, 2017, pp. 132 - 132 (atti di: 6th International Meeting on Quadruplex Nuceic Acids: G4thering., Praga, 31 maggio-03 giugno 2017) [atti di convegno-abstract]

Capranico, Giovanni; Marinello, Jessica; Chillemi, Giovanni, Type I DNA Topoisomerases, «JOURNAL OF MEDICINAL CHEMISTRY», 2017, 60, pp. 2169 - 2192 [articolo]

Capranico, G.; Martegani, E.; Musci, G.; Raugei, G.; Russo, T.; Zambrano, N.; Zappavigna, V., Biologia molecolare, Napoli, Edises srl, 2016, pp. 469 . [libro]

Cristini, Agnese; Park, Joon-Hyung; Capranico, Giovanni; Legube, Gaëlle; Favre, Gilles; Sordet, Olivier, DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions, «NUCLEIC ACIDS RESEARCH», 2016, 44, pp. 1161 - 1178 [articolo]

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