Dissertation topics suggested by the teacher.
1) Development of advanced 3D cell culture techniques (tumor spheroids, organoids, including bioprinting) for the testing of pharmaceuticals, chemicals and nanostructures and for personalized medicine.
2) Development of nanostructures based on the assembly of nucleic acids for intracellular or diagnostic applications (example: interfering with neuroinflammation).
3) Development of atomic force microscopy techniques for the characterization of macromolecules, vesicles and nabostructures, and cells, including the nanomechanical characterization of eukariotic cells.
4) development of biosensors towards biomarkers of interest in cardiology
candidates can also choose amongst internship projects at related laboratories abroad: the projects need to be confirmed and defined in detail at the moment of interest.
- Nanobiophotonics Lab of the Leibnitz Institute at Jena (Germany): biosensor applications of plasmonic nanoparticles.
- Univ. of Edinburgh: availability to be defined
Recent dissertations supervised by the teacher.
First cycle degree programmes dissertations
- Costruzione di un modello cellulare per la caratterizzazione di varianti di significato incerto
- Ottimizzazione di dispositivi point-of-care: biosensori a
flusso laterale per la rilevazione di proteine e acidi
nucleici
- Sviluppo di biosensori a flusso laterale per la rilevazione di micro-RNA
- sviluppo di modelli 3d di carcinoma del
colon-retto e studio dell’effetto di
farmaci antitumorali
- Sviluppo di modelli 3d di carcinoma mammario e studio dell’effetto di farmaci antitumorali
- Sviluppo e caratterizzazione di sferoidi come modello preclinico per lo studio del tumore al seno
Second cycle degree programmes dissertations
- Development of a quantitative point-of-care immunoassay for
Preterm Birth assessment
- Use of DNA nanostructures in modulating microglial activation
