Giampaolo Zuccheri

Giampaolo Zuccheri, PhD
Staff researcher and Adjunct Professor
Nanobioscience Lab

Department of Pharmacy and Biotechnologies, Interdepartmental Center for Industrial Research on Life and Health Sciences 
University of Bologna, Italy.

E-mail: giampaolo(dot)zuccheri(at)unibo(dot)it

Regular Mailing address: Via Irnerio, 48 - Bologna 40126 Italy

Lab and Courier Address: Via S. Giacomo, 11 - Bologna 40126 Italy (how to reach us)

Phone +39-051-20-94388;

http://nanobionano.unibo.it/indexG.html

Role and Affililation: Since 2002, I am a permanent Staff Researcher and Adjunct Professor at the University of Bologna, first with the Faculty of Pharmacy and the Department of Biochemistry and currently with the Department of Pharmacy and Biotechnology. I teach Nanobiotechnology for the degree courses in Molecular Biotechnology and Macromolcular Chemistry for the degree course in Applied Pharmacological Sciences. I am also part of the Nano Institute of the Italian CNR (with the Center at the CNR-University of Modena: Center for Nanostructures and Biosystems at Surfaces) and of the Italian Interuniversity Consortium on Materials Science and Technology.

Previously, I had been a Post Doc studies at the Department of Biochemistry of the University of Bologna with Prof. Bruno Samorì. In 1994-1996 I've been a Research Assistant at the Institute of Molecular Biology of the University of Oregon (U.S.A.) under the supervision of Prof. Carlos Bustamante. I did my Ph.D. in Chemistry at the University of Calabria in Cosenza (Italy) (Thesis dissertation on May 25th, 1998). In 1991-1992, I have been a Research Assistant at the Lawrence Berkeley Laboratory and the University of California at Berkeley under the supervision of Dr. Marcos F. Maestre. I took my undergraduate courses and diploma in Industrial Chemistry Faculty at the University of Bologna (Degree with 110/110 cum laude on March, 11th 1994).

My research interests focus on the chemistry and biophysics of nucleic acids and proteins and on their nanobiotechnological applications.

Awards : In 1994, I was one of the recipients of the annual prize of the Italian Federation of the Chemical Industry (Federchimica) and in 1998 I was awarded the ‘Borsellino prize' of the Italian Society for Pure and Applied Biophysics (SIBPA). I am currently an associated member of the Nanoscience Institute of the Italian CNR (National Research Council), of the Italian Chemical Society (SCI), of the Italian Interuniversity Consortium of Materials Science and Technology (INSTM).

In 2010 I have been a visiting professor at the Ecole Politechnique Federale de Lausanne, Switzerland (EPFL).

Research projects : As a Principal Investigator, I participated in the research of a PRISMA2004 project (Innovative projects on materials science of the Italian Interuniversity Consortium of Materials Science and Technology) on nanostructured material. I also participate and coordinate part of the research of funded European (“NucAN” FP6 NMP-STREP, “DINAMICS” FP6-IP, “BIONICS” Eurocore-SONS) and National research projects (FIRB “COMBATCANCER”).

I am mainly involved in the following topics:

• ultrastructural characterization of nucleic acids and their interactions with other macromolecules and interfaces. The quantitative evaluation of atomic force microscopy (AFM) images and AFM-based force-spectroscopy signals allows the quantitative determination of such parameters as nucleic acids secondary structure, intrinsic curvature and flexibility, contour length, force and energy of interaction with solid interfaces.

• Nanobiotechnological applications of nucleic acids : DNA-based nano-objects and nano-devices are designed, prepared by self-assembly and characterized in the lab. Techniques such as optical microscopy, AFM, AFM-based single-molecule force spectroscopy, fluorescence spectroscopy have been used in such characterizations.

• DNA biosensors . In collaboration with researchers at the Department of Electronics of the University of Bologna, we are testing possible novel methods to integrate electronic read-out strategies with nanotechnology towards novel generations of nucleic acids biosensors amenable of miniaturization.

• biophysical studies on the structure or proteins with single-molecule techniques, such as single-molecule force spectroscopy, including the development of innovative instrumentation and analysis protocols.

Publications List

Papers on peer-reviewed journals (* on papers where serving as the corresponding author)

1. L. Ulfo, A. Cantelli, A. Petrosino, P. E. Costantini, M. Nigro, F. Starinieri, E. Turrini, S. K. Zadran, G. Zuccheri, R Saporetti, M. Di Giosia, A. Danielli, M Calvaresi, (2022) "Orthogonal nanoarchitectonics of M13 phage for receptor targeted anticancer photodynamic therapy" Nanoscale, https://doi.org/10.1039/D1NR06053H
2. A. Abruzzo, B. Giordani, A. Miti, B. Vitali, G. Zuccheri, T. Cerchiara, B. Luppi, F. Bigucci, (2021) "Mucoadhesive and mucopenetrating chitosan nanoparticles for glycopeptide antibiotic administration" International Journal of Pharmaceutics Volume 606, 5 September 2021, 120874, https://doi.org/10.1016/j.ijpharm.2021.120874 .
3. S. Petralla, F. De Chirico, A. Miti, O. Tartagni, F. Massenzio, E. Poeta, M. Virgili, G Zuccheri,* and B. Monti* (2021) "Epigenetics and Communication Mechanisms in Microglia Activation with a View on Technological Approaches" Biomolecules, https://doi.org/10.3390/biom11020306 .
4. A. Miti, S. Thamm, P. Müller, A.Csáki, W. Fritzsche, G. Zuccheri* (2020) "A miRNA biosensor based on localized surface plasmon resonance enhanced by surface-bound hybridization chain reaction" Biosensors and Bioelectronics https://doi.org/10.1016/j.bios.2020.112465
5. G. Aprile, F. F. Lupi, S. Taddei, E. Martinelli, G. Zuccheri, L. Boarino, G. Galli, M. Laus (2019) "Mixed morphology in low molar mass fluorinated block copolymers" Polymer, 179: UNSP 121657 DOI:10.1016/j.polymer.2019.121657 [http://dx.doi.org/10.1016/j.polymer.2019.121657]
6. Pedro M.Castro, Patrícia Baptista, Giampaolo Zuccheri, Ana Raquel Madureira, Bruno Sarmento, Manuela E. Pintado, (2019) "Film-nanoparticle composite for enhanced oral delivery of alpha-casozepine" Colloids and Surfaces B: Biointerfaces. DOI:10.1016/j.colsurfb.2019.05.029 [http://dx.doi.org/10.1016/j.colsurfb.2019.05.029]
7. A. Abruzzo, T. Cerchiara, F. Bigucci, G. Zuccheri, C. Cavallari, B. Saladini, B. Luppi (2019) "Cromolyn-crosslinked chitosan nanoparticles for the treatment of allergic rhinitis" European Journal of Pharmaceutical Sciences, 131: 136-145 doi:10.1016/j.ejps.2019.02.015 [https://doi.org/10.1016/j.ejps.2019.02.015] .
8. F. Massenzio , E. Peña-Altamira, S. Petralla, M. Virgili, G. Zuccheri, A. Miti, E. Polazzi, I. Mengoni , D. Piffaretti, B. Monti "Microglial overexpression of fALS-linked mutant SOD1 induces SOD1 processing impairment, activation and neurotoxicity and is counteracted by the autophagy inducer trehalose" Biochim Biophys Acta Mol Basis Dis. 2018 Oct 10;1864(12):3771-3785. doi: 10.1016/j.bbadis.2018.10.013 [http://dx.doi.org/10.1016/j.bbadis.2018.10.013] .
9. A. Gandini, M. Bartolini, D. Tedesco, L. Martínez-González, C. Roca, N. Campillo, J. Zaldivar-Diez, C. Perez, G. Zuccheri, A. Miti, A. Feoli, S. Castellano, S. Petralla, B. Monti, M. Rossi, F. Moda, G. Legname, A. Martínez, M. L. Bolognesi (2018) "Tau-centric multi-target approach for Alzheimer’s disease: development of first-in-class dual glycogen synthase kinase 3β and tau-aggregation inhibitors" Journal of Medicinal Chemistry, 61, 17, 7640-7656 DOI: 10.1021/acs.jmedchem.8b00610 [http://dx.doi.org/10.1021/acs.jmedchem.8b00610] .
10. F. Ferrarese Lupi, T. Jacopo Giammaria, A. Miti, G. Zuccheri, S. Carignano, K. Sparnacci, G. Seguini, N. De Leo, L. Boarino, M. Perego, and M. Laus (2018) "Hierarchical Order in Dewetted Block Copolymer Thin Films on Chemically Patterned Surfaces [https://pubs.acs.org/doi/10.1021/acsnano.8b02832] " ACS Nano DOI: 10.1021/acsnano.8b02832 [http://dx.doi.org/10.1021/acsnano.8b02832]
11. H. Ahmadzade Kermani, M. Hosseini, A. Miti, M. Dadmehr, G. Zuccheri,
    S. Hosseinkhani, M. Reza Ganjali (2018) "A colorimetric assay of DNA methyltransferase activity based on peroxidase mimicking of DNA template Ag/Pt bimetallic nanoclusters" Analytical and Bioanalytical Chemistry https://doi.org/10.1007/s00216-018-1143-2
12. P. Taddei, S. Tozzi, G. Zuccheri, S. Martinotti, E. Ranzato, V. Chiono, I. Carmagnola, M. Tsukada, (2017) "Intermolecular interactions between B. mori silk fibroin and poly(L-lactic acid) in electrospun composite nanofibrous scaffolds" Materials Science and Engineering C, 70, 777-787. http://dx.doi.org/10.1016/j.msec.2016.09.055
13. K. Sparnacci, D. Antonioli, M. Perego, T. J. Giammaria, G. Seguini, F. Ferrarese Lupi, G. Zuccheri, V. Gianotti, M. Laus (2017) High temperature surface neutralization process with random copolymers for block copolymer self-assembly, Polymer International 66:459-467. http://dx.doi.org/10.1002/pi.5285
14. A. Abruzzo, G. Zuccheri, F. Belluti, S. Provenzano, L. Verardi, F. Bigucci, T. Cerchiara, B. Luppi, N. Calonghi, (2016) “Chitosan nanoparticles for lipophilic anticancer drug delivery: Development, characterization and in vitro studies on HT29 cancer cells” Colloids and Surfaces B: Biointerfaces 145: 362-372. doi:10.1016/j.colsurfb.2016.05.023 [http://dx.doi.org/10.1016/j.colsurfb.2016.05.023] .
15. F. Ferrarese Lupi, G. Aprile, T. J. Giammaria, G. Seguini, G. Zuccheri, N. De Leo, L. Boarino, M. Laus, and M. Perego (2015) "Thickness and microdomain orientation of asymmetric PS-b-PMMA block copolymer films inside periodic gratings" ACS Appl. Mater. Interfaces, 7 (42): 23615–23622. doi:10.1021/acsami.5b07127 [http://dx.doi.org/10.1021/acsami.5b07127]
16. M. Ceresoli, M. Palermo, F. Ferrarese Lupi, G. Seguini, M. Perego, G. Zuccheri, S. D. Phadatare, D. Antonioli, V. Gianotti, K. Sparnacci and M. Laus (2015) "Neutral wetting brush layers for block copolymer thin films using homopolymer blends processed at high temperatures" Nanotechnology 26 (41): 415603 (12 pages)doi:10.1088/0957-4484/26/41/415603 [link [http://dx.doi.org/10.1088/0957-4484/26/41/415603] ]
17. K. Sparnacci, D. Antonioli, V. Gianotti, M. Laus, G. Zuccheri, F. Ferrarese Lupi, T. J. Giammaria, G. Seguini, M. Ceresoli, and M. Perego (2015) "Thermal Stability of Functional P(S-r-MMA) Random Copolymers for Nanolithographic Applications" ACS Appl. Mater. Interfaces, 7 (7), 3920–3930. doi:10.1021/am509088s [link [http://pubs.acs.org/doi/full/10.1021/am509088s] ].
18. Bergamini C., Angelini P., Rhoden KJ, Porcelli AM, Fato R, Zuccheri G.* (2014) "A practical approach for the detection of DNA nanostructures in single live human cells by fluorescence microscopy" Methods. [http://www.ncbi.nlm.nih.gov/pubmed/24440746#] 67(2):185-92 doi: 10.1016/j.ymeth.2014.01.009.
19. Fabio M. Spiga, Attila Bonyár, Balázs Ring, Manuele Onofri, Alessandra Vinelli, Hunor Sántha, Carlotta Guiducci, Giampaolo Zuccheri* (2014) "Hybridization Chain Reaction performed on a metal surface as a means of signal amplification in SPR and electrochemical biosensors." Biosensors and Bioelectronics 54:102-8, doi: 10.1016/j.bios.2013.10.036 [http://dx.doi.org/10.1016/j.bios.2013.10.036] .
20. D. Antonioli, M. Laus, G. Zuccheri, V. Kapeliouchko, M. C. Righetti, L. Boarino, and K. Sparnacci (2012) "Preparation and Properties of PTFE-PMMA Core-Shell Nanoparticles and Nanocomposites," Journal of Nanotechnology (2012) [link [http://www.hindawi.com/journals/jnt/aip/875815/] ] doi:10.1155/2012/875815
    
21. D. Antonioli, M. Laus, K. Sparnacci, S. Deregibus, V. Kapeliouchko, T. Poggio, G. Zuccheri, R. Passeri, L. Boarino (2012) "Preparation and Thermal Characterization of PTFE/PES Nanocomposites" Macromol. Symp. 311, 70–76 DOI: 10.1002/masy.201000104.
22. K. Sparnacci, D. Antonioli, S. Deregibus, M. Laus, G. Zuccheri, L. Boarino, N. Deleo, D. Comoretto (2012) "Preparation, Properties and Self-Assembly Behavior of PTFE- Based Core- Shell Nanospheres" Journal of Nanomaterials Volume 2012 (2012), Article ID 980541, 15 pages [link [http://www.hindawi.com/journals/jnm/2012/980541/] ]
23. J. Jensen, M. Farina, G. Zuccheri, W. Grange, M. Hegner (2012) "Quantitative, Label-Free Detection of the Aggregation of α-Synuclein using Microcantilever Arrays Operated in a Liquid Environment" Journal of Sensors, 2012, Article ID 874086, 7 pages [link [http://downloads.hindawi.com/journals/js/2012/874086.pdf] ]
24. D. Antonioli, M. Laus, K. Sparnacci, S. Deregibus, V. Kapeliouchko, G. Palamone, T. Poggio, G. Zuccheri, R. Passeri, (2010)" Thermal and DMA Characterization of PTFE-PMMA Nanocomposites from Core-Shell Nanoparticles" Macromol. Symp. 2010, 296: 197–202.
25. G. Zuccheri, A. Vinelli, M. Onofri, B. Samorì (2010) "Surface-bound DNA self-assembly or enzymatic reactions toward the PCR-free amplification of nucleic acids biosensor signals" European Cells and Materials, 20(suppl.3), 285 (Scopus: 2-s2.0-84860906240).
26. Laus M., Sparnacci K., Antonioli D., Deregibus S., Kapeliouchko V., Palamone G., Poggio T., Zuccheri G., Passeri R.(2010) "On the Multiple Crystallization Behavior of PTFE in PMMA/PTFE Nanocomposites from Core–Shell Nanoparticles" Journal of Polymer Science: Part B: Polymer Physics, Vol. 48, 548–554.
27. Materassi D., Baschieri P., Tiribilli B., Zuccheri G., Samorì B. (2009) "An open source/real-time atomic force microscope architecture to perform customizable force spectroscopy experiments" Review of Scientific Instruments 80, 084301; doi:10.1063/1.3194046 (also appearing on the Virtual Journal of Biological Physics Research 18(4), 15 August 2009 and on the Virtual Journal of Nanoscale Science & Technology 20(8), 24 August 2009).
28. Kapeliouchko V., Palamone G., Poggio T., Zuccheri G., Passeri R., Sparnacci K., Antonioli D., Deregibus S., Laus M. (2009) "PMMA-based core-shell nanoparticles with various PTFE cores" Journal of Polymer Science: Part A: Polymer Chemistry 47(11): 2928-2937.
29. Sparnacci K., Antonioli D., Deregibus S., Laus M., Poggio T., Kapeliouchko V., Palamone, G., Zuccheri G., Passeri R.,(2009) "PTFE-Based Core−Soft Shell Nanospheres and Soft Matrix Nanocomposites" Macromolecules 42 (10):3518–3524, https://doi.org/10.1021/ma802871y
30. Vinelli, A., Primiceri, E., Brucale M., Zuccheri, G., Rinaldi, R., Samorì, B. (2008) “Sample preparation for the quick sizing of metal nanoparticles by atomic force microscopy” Microscopy Research and Technique 71(12): 870-879 https://doi.org/10.1002/jemt.20631.
    
31. Valle, F., G. Zuccheri, A. Bergia, L. Ayres, A. E. Rowan, R. J. M. Nolte and B. Samori (2008). "A polymeric molecular "Handle" for multiple AFM-based single-molecule force measurements." Angewandte Chemie-International Edition 47(13): 2431-2434. https://doi.org/10.1002/anie.200704526
32. Kolaric, B., M. Sliwa, M. Brucale, R. A. L. Vallee, G. Zuccheri, B. Samori, J. Hofkens and F. C. De Schryver (2007). "Single molecule fluorescence spectroscopy of pH sensitive oligonucleotide switches." Photochemical & Photobiological Sciences 6(6): 614-618. https://doi.org/10.1039/b618689k
33. Mazzocchetti, L., S. Sandri, M. Scandola, A. Bergia and G. Zuccheri (2007). "Radiopaque Organic-Inorganic Hybrids Based on Poly(d,l-lactide)." Biomacromolecules 8(2): 672-8. https://doi.org/10.1021/bm060921n
34. Brucale, M., G. Zuccheri and B. Samori (2006). "Mastering the Complexity of DNA Nanostructures." Trends In Biotechnology 24(5): 235-243.
35. Brucale, M., G. Zuccheri, L. Rossi, A. Bazzani, G. Castellani and B. Samori (2006). "Characterization and modulation of the hierarchical self-assembly of nanostructured DNA tiles into supramolecular polymers." Organic & Biomolecular Chemistry 4(18): 3427-3434. https://doi.org/10.1039/B605744F
36. Ficarra, E., Masotti, D., Macii, E., Benini, L., Zuccheri, G., and Samorì, B. (2005). "Automatic Intrinsic DNA Curvature Computation
    From AFM Images." IEEE Transactions on Medical Engineering. 52(12): 2074-2086.
37. Ficarra, E., L. Benini, E. Macii and G. Zuccheri (2005). "Automated DNA fragments recognition and sizing through AFM image processing." IEEE Transactions on Information Technology in Biomedicine 9(4): 508-517.
38. Zuccheri, G., M. Brucale and B. Samorì (2005). "The Tube or the Helix? This is the Question: Towards the Fully Controlled DNA-Directed Assembly of Carbon Nanotubes." Small 1(6): 590-592
39. Samorì, B. and G. Zuccheri (2005). "DNA Codes for Nanoscience." Angew Chem Int Ed Engl 44(8): 1166-1181. [IF2005: 9.596]
40. Samorì, B., G. Zuccheri and P. Baschieri (2005). "Protein unfolding and refolding under force: methodologies for nanomechanics." Chemphyschem 6(1): 29-34.
41. Brucale, M., G. Zuccheri and B. Samorì (2005). "The dynamic properties of an intramolecular transition from DNA duplex to cytosine-thymine motif triplex." Org Biomol Chem 3(4): 575-7.
42. Giro, A., Bergia, A., Zuccheri, G.,* Bink, H.H., Pleij, C.W. and Samorì, B. (2004). "Single molecule studies of RNA secondary structure: AFM of TYMV viral RNA." Microsc Res Tech 65 (4-5): 235-45. https://doi.org/10.1002/jemt.20123
43. Guiducci, C., Stagni, C., Zuccheri, G., Bogliolo, A., Benini, L., Samorì, B. and Riccò, B. (2004). "DNA detection by integrable electronics." Biosensors and Bioelectronics 19 (8): 781-787. https://doi.org/10.1016/s0956-5663(03)00266-5
44. Ficarra, E., Benini, L., Riccò, B. and Zuccheri, G. (2002). Automated DNA Fragments Recognition and Sizing through AFM Image Processing . 2002 IEEE International Symposium On Biomedical Imaging: pages 453 - 456 (DOI: 10.1109/ISBI.2002.1029292 [http://dx.doi.org/10.1109/ISBI.2002.1029292] ). (peer reviewed published international conference proceeding, ISBN: 0-7803-7584X)
45. Scipioni, A., Zuccheri, G., Anselmi, C., Bergia, A., Samorì, B. and De Santis, P. (2002). "Sequence-dependent DNA Dynamics by Scanning Force Microscopy Time-resolved imaging." Chemistry & Biology 9: 1315-1321.
46. Scipioni, A., Anselmi, C., Zuccheri, G., Samorì, B. and De Santis, P. (2002). "Sequence-dependent DNA curvature and flexibility from scanning force microscopy images." Biophys J 83 (5): 2408-18.
47. Sampaolese, B., Bergia, A., Scipioni, A., Zuccheri, G., Savino, M., Samorì, B. and De Santis, P. (2002). "Recognition of the DNA sequence by an inorganic crystal surface." Proc Natl Acad Sci U S A 99 (21): 13566-70. https://doi.org/10.1073/pnas.202471699
48. Nagami, F., Zuccheri, G., Samorì, B. and Kuroda, R. (2002). "Time-lapse imaging of conformational changes in supercoiled DNA by scanning force microscopy." Anal. Biochem. 300 (2): 170-6. https://doi.org/10.1006/abio.2001.5435
49. Zuccheri, G; Samori, B. (2002) "Scanning force microscopy studies on the structure and dynamics of single DNA molecules" in Atomic Force Microscopy in Cell Biology . B. P. Jena and J. K. H. Hoerber. San Diego (CA) U.S.A., Academic Press. 68: 357-395. Book Series: METHODS IN CELL BIOLOGY (IF:1.258 in 2002)
50. Zuccheri, G., Scipioni, A., Cavaliere, V., Gargiulo, G., De Santis, P. and Samorì, B. (2001). "Mapping the intrinsic curvature and flexibility along the DNA chain." Proc. Natl. Acad. Sci. U S A 98 (6): 3074-3079. https://doi.org/10.1073/pnas.051631198
51. Zuccheri, G., Bergia, A., Gallinella, G., Musiani, M. and Samorì, B. (2001). "Scanning force microscopy study on a single-stranded DNA: the genome of parvovirus B19." Chembiochem 2 (3): 199-204. https://doi.org/10.1002/1439-7633(20010302)2:3%3C199::aid-cbic199%3E3.0.co;2-8
52. Laus, M., Sparnacci, K., Ensoli, B., Buttò, S., Caputo, A., Mantovani, I., Zuccheri, G., Samorì, B. and Tondelli, L. (2001). "Complex associates of plasmid DNA and a novel class of block copolymers with PEG and cationic segments as new vectors for gene delivery." J. Biomaterials Science - Polymer Edition 12 (2): 209-228.
53. L. Barbieri, P. Valbonesi, F. Righi, G. Zuccheri, F. Monti, P. Gorini, B. Samorì and F. Stirpe (2000). “ Polynucleotide:adenosine glycosidase is the sole activity of ribosome-inactivating proteins on DNA.” J. Biochem. 128: 883-889. 10.1093/oxfordjournals.jbchem.a022827 [https://doi.org/10.1093/oxfordjournals.jbchem.a022827] .
54. G. Zuccheri, R. T. Dame, M. Aquila, I. Muzzalupo and B. Samorì (1998). “ Conformational fluctuations of supercoiled DNA molecules observed in real time with a scanning force microscope.” Applied Physics A (Materials Science Processing) 66(suppl., pt.1-2): S585-9.
55. C. Bustamante, G. Zuccheri, S. H. Leuba, G. Yang and B. Samorì (1997). “ Visualization and analysis of chromatin by scanning force microscopy.” Methods, a Companion to Methods in Enzymology 12(1): 73-83. https://doi.org/10.1006/meth.1997.0449
56. B. Samorì, I. Muzzalupo and G. Zuccheri (1996). “ Deposition of supercoiled DNA on mica for scanning force microscopy imaging.” Scanning Microscopy 10(4): 953-962.
57. I. Muzzalupo, C. Nigro, G. Zuccheri, B. Samorì, C. Quagliariello and M. Buttinelli (1995). “ Deposition on mica and scanning force microscopy imaging of DNA molecules whose original B structure is retained.” Journal of Vacuum Science & Technology A (Vacuum, Surfaces, and Films) 13(3, pt.2): 1752-4.
58. G. Zuccheri, G. A. Ranieri, C. Nigro and B. Samorì (1995). “ Writhing number of supercoiled DNA from its scanning force microscopy imaging.” Journal of Vacuum Science & Technology B (Microelectronics and Nanometer Structures) 13(1): 158-60.
59. B. Samorì, C. Nigro, V. Armentano, S. Cimieri, G. Zuccheri and C. Quagliariello (1993). “DNA supercoiling imaged in 3 Dimensions by scanning force microscopy.” Angewandte Chemie-International Edition In English 32(10): 1461-1463.

 

Book Sections

1. Andrea Miti and Giampaolo Zuccheri (2018) "Hybridization Chain Reaction Design and Biosensor Implementation" pages 115-135 in "DNA Nanotechnology, Methods and Protocols [https://www.springer.com/us/book/9781493985814] " by Giampaolo Zuccheri (Ed.) Springer 2018, Series: Methods in Molecular Biology, Volume 1811, DOI:10.1007/978-1-4939-8582-1_8 [https://doi.org/10.1007/978-1-4939-8582-1_8] .
2. Daniele Gazzola, Simone Bonetti and Giampaolo Zuccheri (2012) "Electrochemical biosensor strategies for pathogen detection in water security" in "Detection of Pathogens in Water Using Micro and Nano-Technology" G. Zuccheri and N. Asproulis (Eds.) ISBN: 9781780401089.
3. Alessandra Vinelli, Manuele Onofri and Giampaolo Zuccheri (2012) "Biochemical and Nanotechnological Strategies for Signal Enhancement in the Detection of Nucleic Acids with Biosensors" in "Detection of Pathogens in Water Using Micro and Nano-Technology" G. Zuccheri and N. Asproulis (Eds.), ISBN: 9781780401089.
4. Passeri, R., Brucale, M., Zuccheri, G. Samorì, B. “DNA-based Parallelograms: a Retrospective or a Perspective?” in DNA-based Nanodevices: International Workshop on DNA-Based Molecular Construction, Jena, D, AIP Conference Proceedings (2008) vol. 1062, pp. 58-64 (ISBN: 978-0-7354-0592-9). 
5. Zuccheri G, Brucale M, Vinelli A, Samorì B, (2006) “DNA-based Artificial Nanostructures” Annual Reviews of Nano Research , 1, 531-572.
6. F. Valle, G. Zuccheri, B. Samorì, (2006) “Dalle Cellule alle Molecole: alla Scoperta della Struttura delle Molecole Biologiche e delle loro Interazioni con la Microscopia a Forza Atomica” pages 207-218 in “1956-2006 Cinquanta anni di microscopia in Italia tra storia, progresso ed innovazione.” ISBN 978-88-7963-215-7.
7. Samorì, B., Zuccheri, G., Scipioni, A. and De Santis, P. (2006). Towards an Increase of the Hierarchy in the Construction of DNA-Based Nanostructures through the Integration of Inorganic Materials. Nanotechnology: Science and Computation . J. Chen, N. Jonoska and G. Rozenberg. Berlin Heidelberg, Springer: 249-259.
8. Sandal, M., Zuccheri, G. and Samorì, B. (2005). Inside the Small Length and Energy scales of the World of the Individual Biological Molecules. From Cells to Proteins: Imaging Nature across Dimensions . V. Evangelista, L. Barsanti, V. Passarelli and P. Gualteri, Springer, Verlag. 3: 111-137.
9. Grandi, F., Bergia, A., Giro, A., Zuccheri, G. and Samorì, B. (2003). “Scanning force microscopy studies of the adsorption and desorption of DNA at solid-liquid interfaces.” AIP Conference Proceedings 696: 172-9.
10. G. Zuccheri, F. Grandi, A. Bergia, B. Samorì (2003) “The Structure and the Interactions of the Biological Macromolecules Studied with the Scanning Force Microscope.” Pag. 399-410 In “Ricordo di Alessandro Bertoluzza” CLUEB Bologna ISBN 88-491-2112-1.
11. Zuccheri, G. and Samorì, B. (2002). Scanning force microscopy studies on the structure and dynamics of single DNA molecules. Atomic Force Microscopy in Cell Biology . B. P. Jena and J. K. H. Hoerber. San Diego (CA) U.S.A., Academic Press. 68: 357-395.
12. Zuccheri, G., Bergia, A., Scipioni, A., De Santis, P. and Samorì, B. (2002). “DNA on surfaces: Adsorption, Equilibration and Recognition Processes from a Microscopist's View”. DNA-BASED MOLECULAR CONSTRUCTION: International Workshop on DNA-Based Molecular Construction, Jena, D, AIP Conference Proceedings 640: 23-37.
13. Zuccheri, G., Bergia, A. and Samorì, B. (2002). Scanning Force Microscopy Studies of the Structure of Biological macromolecules. Seminars in Organic Synthesis . L. Lopez. Milano, Società Chimica Italiana. XXVII: 7-15.

Articles on popular science magazines

Zuccheri, G., Bergia, A. and Samorì, B. (2001). “La Struttura delle molecole biologiche.” (trans: “The structure of biological molecules”) Le Scienze – Quaderni (spin-off publication of the Italian edition of Scientific American): 58-62.

Edited Books

1. "DNA Nanotechnology, Methods and Protocols [https://www.springer.com/us/book/9781493985814] " by Giampaolo Zuccheri (Ed.) Springer 2018, Series: Methods in Molecular Biology, Volume 1811, DOI:10.1007/978-1-4939-8582-1, ISBN: 978-1-4939-8582-1 (e-b ook) 978-1-4939-8581-4 (hardcover)

2. "DNA Nanotechnology, Methods and Protocols [https://www.springer.com/us/book/9781617791413] " by Giampaolo Zuccheri and Bruno Samorì (Eds.). Springer 2011. Series: Methods in Molecular Biology, Volume 749, DOI: 10.1007/978-1-61779-142-0. ISBN 978-1-61779-141-3 (Print) 978-1-61779-142-0 (Online). [link out [http://www.springerlink.com/content/m41562/] ]

3. "Detection of Pathogens in Water Using Micro and Nano-Technology"
Giampaolo Zuccheri and Nikolaos Asproulis (Eds.) Publication Date: 15 Aug 2012 • ISBN: 9781780401089 Pages: 316 • Paperback [link out [http://www.iwapublishing.com/template.cfm?name=isbn9781780401089&type=category] ]

Patents

Co-inventor in: "FOSFORAMMIDITI DELL'NTA E RELATIVI CONIUGATI, LORO PREPARAZIONE ED USO"
Inventors: Massimo Capobianco, Laura Fiume, Bruno Samorì, Giampaolo Zuccheri
Ownership: Consiglio Nazionale delle Ricerche
Patent ID: IT2001FI00145

Co-inventor in: "USE OF DNA OR FRAGMENTS OR ANALOGS THEREOF AS A MOLECULAR GLUE"
Inventors: SAMORI BRUNO [IT]; ZUCCHERI GIAMPAOLO [IT]; MUELLEN KLAUS [DE];
HERMANN ANDREAS [DE]
Ownership: Alma Mater Studiorum Università di Bologna, MAX PLANCK GESELLSCHAFT
Patent ID: WO2006IB00275

Co-inventor in:"SUPPORTO PER UN SENSORE DI MISURAZIONE"
Inventors: Sandro Carrara, Bruno Samorì, Claudio Stagni Degli Esposti, Giampaolo Zuccheri
Ownership: ALMA MATER STUDIORUM UNI DI BOLOGNA
Patent ID: T2007BO00091 20070216

Co-inventor in: "REFERENCE-STANDARD DEVICE FOR CALIBRATION OF
MEASUREMENTS OF LENGTH, AND CORRESPONDING CALIBRATION PROCESS"
Inventors: Luca Boarino, Federico Lupi Ferrarese, Giulia Aprile, Natascia De Leo, Michele Perego,
Michele Laus, Giampaolo Zuccheri
Ownership: Istituto Nazionale di Ricerca Metrologica.