Main research interests
Pharmacoepidemiology and pharmacovigilance studies: pharmacodilization studies in hospitals and in the general population of various classes of drugs (antibiotics, anti-asthmatics, antidepressants, non-steroidal anti-inflammatory drugs, antihypertensives, anti-migraine) in collaboration with national and foreign bodies and with scientific societies (SIF, SIFO) . Spontaneous safety studies of drugs and vaccines on national (AIFA) and international databases (VIGI-Base and FDA-AERS, EudraVigilance) with application of statistical methods of data-mining recognized by international literature. Participation in the national and European network for the systematic evaluation of pharmacovigilance signals.
Clinical pharmacology studies: evaluation of the therapeutic innovation of drugs and application of the model to drugs authorized by the EMEA, studies on adherence to chronic cardiovascular therapies. Participation as scientific and organizational referent for the Participating Center of Bologna (2008) in the three-year multicenter case-control study, entitled "Case-control study on acute serious drug-induced liver injury" in collaboration with the Universities of Verona (Coordinating Center), Naples and Florence (AIFA Call for Independent Research 2008, Protocol FARM8B2TY7). Scientific and methodological collaboration for the realization of a multicenter prospective observational study entitled "Biosimilar erythropoietins vs originator: methods of use and comparative evaluation of safety data in daily clinical practice in nephrology" funded by the SIFO Foundation in January 2014.
Studies in the field of ethics and methodology of clinical trials: analysis of requests for compassionate use, multi-year evaluations of non-commercial clinical studies at the CE, studies on orphan drugs.
