Domenico Motola

Associate Professor

Department of Medical and Surgical Sciences

Academic discipline: BIO/14 Pharmacology

Director of First Cycle Degree of Nursing

Research

Keywords: Pharmacovigilance Drug innovation Drug utilization Pharmacoepidemiology Clinical Pharmacology

Main research interests

Pharmacoepidemiology: drug-utilisation surveys to assess the pattern and the appropriateness of drug use in general practice and in secondary care. Main classes of interest: NSAIDs, cardiovascular drugs, antidepressants, disease modifying in multiple sclerosis, drugs for migraine).
Clinical pharmacology: identification of a method for assessing the degree of therapeutic innovation of new of drugs and application of the method to drugs approved by the European Medicines Agency; participation in a multicenter case-control study entitled “Case-control study on acute serious drug-induced liver injury” (code FARM8B2TY7, financed under the 2008 Calls for independent research on drugs by Italian Drug Agency.
Pharmacovigilance : data mining of local and foreign spontaneous databases; observational studies to evaluate the efficacy and the risk of drugs in clinical practice: among the others, drug induced hepatotoxicity, drug-induced anaphylaxis, safety profile of antiepileptics, safety profile of thiazolidinediones, statin-associated gynecomastia.