Foto del docente

Carmela Fimognari

Full Professor

Department for Life Quality Studies

Academic discipline: BIO/14 Pharmacology

Curriculum vitae

EDUCATION

1993: BS in Medicinal Chemistry University of Bologna; 1997: Ph.D. in Toxicology, University of Bologna; visiting Scientist (1996, 1997, 2000, 2002) at the GSF-National Research Center for Environment and Health, Munich, Germany.

POSITIONS HELD

1993-1998: Lecturer in Pharmacology and Toxicology, University of Bologna, Italy

1998-2014: Assistant Professor of Pharmacology, University of Bologna, Italy

2014-2021: Associate Professor, University of Bologna, Italy

2021-: Full Professor, Department for Life Quality Studies, University of Bologna, Italy

2019-2023: Coordinator of the PhD Programme of Science and Culture of Well-being and Lifestyles, University of Bologna, Italy

2022-2023: Coordinator of the PhD Programme of Sport, Health and Well-being, University of Bologna, Italy.

2020-2022: Member of the Groups of evaluation experts (GEV) in the Italian Evaluation of Research Quality 2015-2019 (VQR)

2021-2023: Member of the Qualification Committee for the procedure for obtaining the national scientific qualification to function as associate or full professor in Italian Universities for the Italian Ministry of Education, universities and research (MIUR), Academic discipline: BIO/14 Pharmacology

2021-present: Deputy Director of the Department for Life Quality Studies, University of Bologna, Italy

SCIENTIFIC MEMBERSHIPS

Italian Society of Toxicology (SITOX)

Italian Society of Pharmacology (SIF)

Italian Society for Clinical Cell Analysis (ISCCA)

European society for clinical cell analysis (ESCCA)

RESEARCH TOPICS

1) Cellular and Genetic Toxicology

- Investigation of critical cellular and molecular events related to carcinogenesis induced by exposure to xenobiotics (drugs, phytochemicals, pesticides, etc.).

- Study of the risk of cancer in exposed populations by using biomarkers of effect.

2) Antitumor Pharmacology

- Identification of plant-derived compounds with potential cancer chemopreventive activity and definition of their mechanism of action at cellular and molecular levels.

- Preclinical development of phytochemicals and their synthetic derivatives as antitumor drugs.

HONORS AND AWARDS

  • 2021: Journal for ImmunoTherapy of Cancer (JITC) Best Basic Tumor Immunology Paper Award 2021 for the article Efimova I., Catanzaro E., Van der Meeren L., Turubanova V.D., Hammad H., Mishchenko T.A., Vedunova M.V., Fimognari C., Bachert C., Coppieters F., Lefever S., Skirtach A.G., Krysko O., Krysko D.V. (2020). Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity. J Immunother Cancer. 8(2):e001369. doi: 10.1136/jitc-2020-001369.
  • 2020: Marine Drugs Best Paper Award 2019 for the article Calcabrini C, Catanzaro E, Bishayee A, Turrini E, Fimognari C. (2017). Marine sponge natural products with anticancer potential: an updated review. Mar Drugs. 15(10):pii: E310. doi: 10.3390/md15100310.
  • 2018: Member of the International Natural Product Sciences Taskforce, bringing together scientists and key opinion leaders of the natural product scientific research field, as well as representatives of multiple scientific excellence centers and pharmaceutical and natural product-related industry. Major aims of the taskforce are to promote collaborative natural product-focused research and science communication.
  • 2017: The article Fimognari C., Lenzi M., Ferruzzi L., Turrini E., Scartezzini P., Poli F., Gotti R., Guerrini A., Carulli G., Ottaviano V., Cantelli-Forti G., Hrelia P. (2011). Mitochondrial pathway mediates the antileukemic effects of Hemidesmus indicus, a promising botanical drug. PLoSOne 6(6): e21544 is among the top 25% most cited PLOS ONE articles.
  • 2012-2015: Advisory Board member of "The Halifax Project", focused on an advanced anticancer therapeutic design that will be aimed at a broad-spectrum of targets in an attempt to tackle the problem of therapeutic resistance and disease relapse.
  • 2008: “Top Ten Cited Author in 2007 & 2008” in Mutation Research Reviews for the paper Fimognari C., Hrelia P. (2007). Sulforaphane as a promising molecule for fighting cancer. Mutat Res-Rev Mutat 635: 90-104.
  • 2001: Recipient of the Italian Society of Pharmacology Award for the best paper published in the journal “Pharmacological Research” in 2000 for the paper Fimognari C., Nüsse M., Cantelli-Forti G, Hrelia P. (2000). New in vitro approaches to explore cellular and molecular events related to carcinogenesis. Pharmacol Res 41: 385-390.
  • 2000: Recipient of the Italian Society of Toxicology Award for the best paper published in 1999 for the paper Fimognari C., Nüsse M., Hrelia P. (1999). Flow cytometric analysis of genetic damage, effect on cell cycle progression and apoptosis by Thiophanate-methyl in human lymphocytes. Env Mol Mutagen 33: 173-176.

SCIENTIFIC PRODUCTION AND METRICS (Scopus, 21.03.24)

N° of original articles: 155

N° of original articles on indexed and peer-reviewed journals: 135

N° of nationwide book chapters: 6

N° of international book chapters: 10

N° of short communications: 2

Citations: 5229

h-index: 36

TEACHING ACTIVITY

Undergraduate Courses

  • Food Toxicology, Second cycle degree programme (LM) in Human Nutrition, Well-Being and Health (2022-present)
  • General Pharmacology, First cycle degree programme (L) in Exercise and Sport Sciences, University of Bologna (2017-present)
  • Pharmacology in Sport, Second cycle degree programme (LM) in Sciences and Techniques of Sports Activities, University of Bologna (2019-present)
  • Toxicology and Prevention of Doping, Second cycle degree programme (LM) in Wellness and Sport Management, University of Bologna (2020-present)
  • Pharmacognosy, Single cycle degree/Combined Bachelor and Master in Pharmacy, University of Bologna, Rimini campus (2015-2021)
  • Food Toxicology, Single cycle degree/Combined Bachelor and Master in Pharmacy, University of Bologna, (2013-2015)
  • Applied Toxicology, Single-cycle degree/Combined Bachelor and Master in Pharmacy, University of Bologna, (2008-2013)
  • Toxicology, Single cycle degree/Combined Bachelor and Master in Pharmacy, University of Bologna, Rimini campus (2008-present)
  • Environmental and Food Toxicology, Single cycle degree/Combined Bachelor and Master in Pharmacy, University of Bologna, Rimini campus (2006)
  • Environmental and Occupational Toxicology, Single-cycle degree/Combined Bachelor and Master in Chemistry and Pharmaceutical Technologies, University of Bologna (2001-2005)
  • Methods in Toxicology, Single cycle degree/Combined Bachelor and Master in Chemistry and Pharmaceutical Technologies, University of Bologna (2000-2001)
  • Toxicology, First cycle degree/Bachelor in Quality Control of Health Products, University of Bologna, Rimini campus (2005-2018)
  • Applied Toxicology, First cycle degree/Bachelor in Quality Control of Health Products, University of Bologna, Rimini campus (2014-2016)
  • Environmental Toxicology and Toxicological Chemistry, Second cycle degree/Two-year Master in Resource Economics and Sustainable Development, University of Bologna, Rimini campus (2015-2016)
  • Good Practices in Lab-Based Activities, First cycle degree/Bachelor in Quality Control of Health Products, University of Bologna, Rimini campus (2007-2010)
  • Toxicology, Second cycle degree/Two- year Master in Pharmaceutical Biotechnology, University of Bologna (2002-2005)
  • Pharmacology of gastrointestinal and urinary systems, First cycle degree/Bachelor in Herbal Medicines, University of Bologna (1999-2001)

    Postgraduate Schools

  • Carcinogenesis, Mutagenesis and Teratogenesis I, Specialization School in Toxicology, University of Bologna (2001-2004)
  • Toxicology, Specialization School in Hospital Pharmacy, University of Bologna (1999-2008)

    Teaching in Master Courses

  • Food Safety, Master in Nutrition, Plant Therapy and Food Supplements, University of Bologna (2015-present)
  • Principles of Toxicology of medicinal plants, Master in Non-conventional medicines, University of Bologna and University of Rome La Sapienza (2011)
  • Genotoxic risk assessment and EC white book on chemical substances, Master in Science, Technologies and Management, University of Ferrara and Montell (2004-2007)
  • Toxic substances in the food chain, Master in Human Nutrition and Food Safety, UNI.TU.RIM., Rimini (2006)
  • Food and reduction of cancer risk, Master in Evaluation and assessment of toxicological risk for environmental pollutants, University of Pavia (2005 and 2006)
  • Safety and Innovation, Master in Pharmaceutical management and health policies, UNI.TU.RIM., Rimini (2003 and 2004)

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