Carlo Ventura

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Publications prior to 2004

1.          Guarnieri C., Flamigni F., Ventura C., Rossoni Caldarera C.: Inhibition of rat heart superoxide dismutase activity by diethyldithyocarbamate and its effects on mitochondrial function. Biochem. Pharmacol. 30: 2174-2176, 1981.

2.          Rossoni Caldarera C., Curello S., Ventura C., Casmiro M., Guarnieri C.: Modification of rat heart metabolism following inhibition of superoxide dismutase activity by diethyldithyo carbamate. In: “Advances on Studies on Heart Metabolism”. Clueb Press, Bologna, pp 441-447, 1982.

3.          Bernardi P., Ghezzi F., Grimaldi R., Minelli C., Ligabue A., Ventura C., Muscari C., Facchinetti F., Petraglia F., Genazzani A.R., Lenzi S.: Endogenous opioids: Clinical and therapeutical implications in acute myocardial infarction. In: “Atherosclerosis and Cardiovascular Diseases”. S. Lenzi and G.C. Descovich Eds. M.T.P. Press, pp 379-392, 1983.

4.          Guarnieri C., Ventura C.: Formation of adrenochrome by bovine cardiac sarcolemma. Biochem. Biophys. Res. Commun. 120: 22-27, 1984.

5.          Ventura C., Georgountzos A., Guarnieri C.: Stimulation by doxorubicin of adrenochrome formation by bovine heart sarcolemma. Biochem. Pharmacol. 33: 3707-3709, 1984.

6.          Bernardi P., Bastagli L., Ghezzi F., Grimaldi R., Mainardi M.A., Cavazza M., Ventura C., Clo C., Danieli A.: Changes in PGE2urinary excretion and renal function in coronary artery disease. Advances in Prostaglandin, Thromboxane and Leukotriene Research 13: 89-91, 1985.

7.          Ventura C., Guarnieri C., Caldarera C.M.: Inhibitory effect of superoxide radicals on cardiac myofibrillar ATPase activity. Ital. J. Biochem. 34: 267-274, 1985.

8.          Guarnieri C., Ventura C., Georgountzos A., Muscari C., Budini R.: Involvement of superoxide radicals in adrenochrome formation, stimulated by arachidonic acid, in bovine cardiac sarcolemmal vescicles. Biochim. Biophys.Acta838: 355-360, 1985.

9.          Guarnieri C., Ventura C.: Inhibition by ceruloplasmin of the cardiac sarcolemmal adrenochrome formation. Bioscience Rep.5: 473-476, 1985.

10.       Clo C., Muscari C., Tantini B., Pignatti C., Bernardi P., Ventura C.: Reduced mechanical activity of perfused rat heart following morphine or enkephalin peptide administration. Life Sci. 37: 1327-1333, 1985.

11.       Guarnieri C., Muscari C., Ventura C., Mavelli I.: Effect of ischemia on heart submitochondrial superoxide formation. Free Rad. Res. Commun.1: 123-128, 1985.

12.       Guarnieri C., Ventura C., Muscari C., Caldarera C.M.: Superoxide-dependent adrenochrome formation in bovine heart sarcolemmal membranes: effect of arachidonic acid. In: “Superoxide and Superoxide Dismutase in Chemistry Biology and Medicine”.G. Rotilio Ed. (Elsevier Publishers B.V. Biomedical Division) pp 416-418, 1986.

13.       Guarnieri C., Muscari C., Ventura C., Caldarera C.M.: Mitochondrial superoxide production in ischemic and reperfused rabbit heart. Proceedings of the Workshop on : Oxygen Radicals in Shock.Int. Workshop. Novelli and Ursini Eds., Florence 1985,pp 165-168, 1986.

14.       Bernardi P., Ghezzi F., Bastagli L., Grimaldi R., Cavazza M., Clo C., Ventura C., Capelli M.: Effects of polyunsatured fatty acids and prostaglandin synthesis on renal function. Prostaglandins Leukotriene and Medicine22: 235-248, 1986.

15.       Ventura C., Guardigli G., Fontana F., Cavazza M., Bastagli L., Turinetto B., Bernardi P.: Enzymic analysis of myofibrillar Ca2+-dependent ATPase activity in atrial specimens from patients with coronary or valvular heart disease. In : “Atherosclerosis and Cardiovascular Diseases”.Vol. 3, S. Lenzi and G.C. Descovich Eds., Editrice Compositori, Bologna, pp 105-110, 1987.

16.       Ventura C., Muscari C., Spampinato S., Bernardi P., Guarnieri C., Caldarera C.M.: Effect of naloxone and opioid peptides on the isolated rat heart contractility. J. Mol. Cell. Cardiol. 19 (3): 307, 1987.

17.       Cavazza M., Fontana F., Guardigli G., Ventura C., Bastagli L., Spagnolo N., Capelli M., Bernardi P.: Myoglobinemia alterations in patients with coronary artery disease and various non ischemic illness. In: “Atherosclerosis and Cardiovascular Diseases”.Vol. 3, S. Lenzi and G.C. Descovich Eds. Editrice Compositori, Bologna, pp 101-104, 1987.

18.       Spampinato S., Ventura C., Fontana F., Guardigli G., Bastagli L., Cavazza M., Bernardi P.: Evidence for the presence of dynorphin in human heart. In: “Atherosclerosis and Cardiovascular Diseases”.Vol. 3, S. Lenzi and G.C. Descovich Eds., Editrice Compositori, Bologna, pp 427-430, 1987.

19.       Fontana F., Guardigli G., Spagnolo N., Ventura C., Cavazza M., Bastagli L., Capelli M., Patrono D., Bernardi P., Lenzi S.: Effect of atrial natriuretic peptide on the cardiovascular and renal function in patients with chronic heart failure. In: “Atherosclerosis and Cardiovascular Diseases”.Vol. 3, S. Lenzi and G.C. Descovich Eds., Editrice Compositori, Bologna, pp 917-921, 1987.

20.       Fontana F., Spagnolo N., Guardigli G., Ventura C., Cavazza M., Bastagli L., Capelli M., Bernardi P., Lenzi S.: Analysis of the plasmatic levels of atrial natriuretic factor in patients with different cardiac diseases. In: “Atherosclerosis and Cardiovascular Diseases”.Vol. 3, S. Lenzi and G.C. Descovich Eds., Editrice Compositori, Bologna, pp 961-963, 1987.

21.       Ventura C., Muscari C., Spampinato S., Bernardi P., Caldarera C.M.: Effects of naloxone on the mechanical activity of isolated rat hearts perfused with morphine or opioid peptides. PEPTIDES8: 695-699, 1987.

22.       Ventura C., Muscari C., Spampinato S., Bernardi P., Caldarera C.M.: Inhibitory action of opioid peptides on ouabain-sensitive Na+-K+and Ca2+-dependent ATPase activities in bovine cardiac sarcolemma. PEPTIDES8: 709-713, 1987.

23.       Ventura C., Bastagli L., Spampinato S., Guardigli G., Cavazza M., Bernardi P., Caldarera C.M.: Analysis of azide-insensitive Ca2+-dependent ATPase activity in atrial specimens from patients with coronary or valvular heart disease. Life Sci. 41: 1257-1263, 1987.

24.       Guarnieri C., Fraticelli A., Ventura C., Vaona I., Budini R.: External GSSG enhances intracellular glutathione level in isolated cardiac myocytes. Biochem. Biophys. Res. Commun. 147: 658-665, 1987.

25.       Ventura C., Muscari C., Cavazza M., Bastagli L., Bernardi P.: Effetti della morfina e di oppioidi endogeni sulla attività meccanica di cuori isolati e perfusi di ratto. Cardiolgia 32: 95-99, 1987.

26.       Muscari C., Bastagli L., Ventura C., Bernardi P., Caldarera C.M.: Riduzione della velocità di respirazione mitocondriale in cuori di ratto perfusi con oppioidi o naloxone. Cardiologia33: 353-357, 1988.

27.       Ventura C., Bastagli L., Caldarera C.M.: Opioids stimulate sarcolemmal NAD(P)H-vanadate dehydrogenase activity. Basic Res. Cardiol. 83: 376-383, 1988.

28.       Ventura C., Bastagli L., Bernardi P., Caldarera C.M., Guarnieri C.: Opioid receptors in rat cardiac sarcolemma: Effect of phenylephrine and isoproterenol. Biochim. Biophys. Acta 987: 69-74, 1989.

29.       Ventura C., Bastagli L., Bernardi P., Caldarera C.M., Guarnieri C.: Opioid receptors in cardiac sarcolemma. J. Endocrinol. Invest. 12: 149-152, 1989.

30.       Guardigli G., Fontana F., Ventura C., Spagnolo N., Bastagli L.,Puddu P., Bernardi P.: Endogenous opioids and hypertensive crises in patients with acute cerebrovascular accidents. J. Endocrinol. Invest. 12: 9-12, 1989.

31.       Ventura C., Bastagli L., Bernardi P., Caldarera C.M., Guarnieri C.: Catecholamines affect the binding of opioids to delta and kappa receptors in rat heart sarcolemmal membranes. J. Mol. Cell. Cardiol. 21(2): 540, 1989.

32.       Ventura C., Spurgeon H.A., Lakatta E.G., Capogrossi M.C.: Calcium release from the sarcoplasmic reticulum mediates the negative inotropic effect of leucine-enkephalin on myocardial cell. CIRCULATION80(II): 446, 1989.

33.       Ventura C., Spurgeon H.A., Lakatta E.G., Capogrossi M.C.: Specific opioid receptor agonists alter the twitch and cytosolic Ca2+transient of rat myocytes. CIRCULATION 80 (II): 196, 1989.

34.       Ventura C., Hano O., Spurgeon H.A., Klockow M., Lakatta E.G., Capogrossi M.C.: Novel drug enhances contraction without changing calcium in guinea pig myocytes. CIRCULATION80(II): 506, 1989.

35.       Ventura C., Guarnieri C., Bastagli L., Bernardi P., Puddu P., Caldarera C.M.: Calcium stimulates opioid receptor agonism in rat cardiac sarcolemma. CARDIOSCIENCE1: 151-154, 1990.

36.       Bastagli L., Ventura C., Muscari C., Caldarera C.M., Puddu P.: Receptors for atrial natriuretic factor in cardiomyocytes and aortic smooth muscle. CARDIOSCIENCE  1: 177-181, 1990.

37.       Spampinato S., Canossa M., Ventura C., Bachetti T., Venturini R., Bastagli L., Bernardi P., Ferri S.: Heterogeneity of immunoreactive dynorphin B-like material in human, rat, rabbit and guinea-pig heart. Life Sci.48: 551-559, 1990.

38.       Ventura C., Guarnieri C., Lakatta E.G., Capogrossi M.C.: Opioid receptor agonist releases calcium from an intracellular pool and increases the Ins(1,4,5)P3 level in rat cardiac myocytes. J. Mol. Cell. Cardiol. 22(III): 1990.

39.       Ventura C., Guarnieri C., Spurgeon H.A., Lakatta E.G., Capogrossi M.C.: Opioid receptor agonist causes intracellular release of Ca2+in cardiac myocytes and neuronal cells. Biophysical Journal57: 294, 1990.

40.       Ventura C., Guarnieri C., Lakatta E.G., Capogrossi M.C.: An increase in inositol-1,4,5-trisphosphate accompanies k opioid alterations in Ca2+homeostasis in cardiac mycoytes. CIRCULATION 82(4): 141, 1990.

41.       Ventura C., Capogrossi M.C., Gambassi G., Spurgeon H.A.,Lakatta E.G.: Novel thiazinone derivatives differentially modify the contractile response to calcium in intact cardiac cells. CIRCULATION82(4): 142, 1990.

42.       Ventura C., Capogrossi M.C., Ferroni C., Guarnieri C., Caldarera C.M.: Spermine decreases twitch amplitude and cytosolic Ca2+transient in rat cardiac myocytes. Ital. J. Biochem. 39: 280-282, 1990.

43.       Ventura C., Capogrossi M.C., Spurgeon H.A., Lakatta E.G.: Opioid peptide increases pH and contractile response to calciumin cardiac myocytes. Biophysical Journal 59 (2): 434, 1991.

44.       Ferroni C., Hano O., Ventura C., Lakatta E.G., Klockow M., Spurgeon H.A., Capogrossi M.C.: A novel positive inotropic substance enhances contractility without increasing the Ca2+transient in rat myocardium. J. Mol. Cell. Cardiol. 23: 325-331, 1991.

45.       Ventura C., Spurgeon H.A., Lakatta E.G., Capogrossi M.C.: Calcium release from the sarcoplasmic reticulum causes a negative inotropic effect in rat ventricular myocytes. Atti del III Workshop Nazionale: I PeptidiOppioidi nei Liquidi Biologici: Fisiopatologia e Clinica.pp 105-110, 1991.

46.       Ventura C., Mazzanti G., Negroni G., Rossoni C., Capogrossi M.C., Guarnieri C.: Negative inotropic effect of a macrocyclic polyamine in isolated rat cardiac myocytes. Life Chemistry Reports 9: 91-96, 1991.

47.       Ferroni C., Ventura C., Sisini A., Caldarera C.M., Capogrossi M.C.: Spermine and spermidine decrease the cytosolic Ca2+transient and have a negative inotropic effect in rat cardiac myocytes. Life Chemistry Reports9: 97-102, 1991.

48.       Ventura C., Capogrossi M.C., Spurgeon H.A., Lakatta E.G.: k-Opioid receptor stimulation increases pH and myofilament Ca2+sensitivity  in cardiac myocytes. Am. J. Physiol.261: H1671-H1674, 1991.

49.       Ventura C., Guarnieri C., Stefanelli C., Cirielli C., Lakatta E.G., Capogrossi M.C.: Comparison between alpha-adrenergic- and k-opioidergic-mediated inositol (1,4,5)- P3/inositol(1,3,4,5)P4formation in adult cultured rat ventricular cardiomyocytes. Biochem. Biophys. Res. Commun.179: 972-978, 1991.

50.       Ventura C., Spurgeon H.A., Lakatta E.G., Guarnieri C., Capogrossi M.C.: Kappa and delta opioid receptor stimulation affects cardiac myocyte function and Ca2+release from an intracellular pool in myocytes and neurons. Circ. Res.70: 66-81, 1992.

51.       Ventura C., Miller R., Wolf H.P., Beier N., Jonas R., Klockow M., Lues I., Hano A., Spurgeon H.A., Lakatta E.G., Capogrossi M.C.: Novel diazinone derivatives separate myofilament Ca2+sensitization and phosphodiesteraase III inhibitory effects in guinea-pig myocardium. Circ. Res.70: 1081-1090, 1992.

52.       Kasper E., Ventura C., Ziman B.D., Lakatta E.G., Weisman H., Capogrossi M.C.: Effect of U-50,488H on the contractile response of cardiomyopathic hamster ventricular myocytes. Life Sci.50: 2029-2035, 1992.

53.       Ventura C., Gambassi G., Spurgeon H.A., Lakatta E.G., Capogrossi M.C.: Opposite effects of delta and kappa opioid receptor stimulation on cytosolic pH in myocardial cells. CIRCULATION84: 389, 1992.

54.       Ventura C., Capogrossi M.C., Lakatta E.G.: Myocardial function and endogenous opioids. In: “Clinical Perspectives in Endogenous Opioid Peptides”.M. Negri, G. Lotti and A. Grossman Eds. John Wiley & Sons Publishers,pp 393-406, 1992.

55.       Ventura C., Canossa M., Vaona I., Carboni L., Caldarera C.M., Spampinato S., Guarnieri C.: Prodynorphin mRNA is synthesized in adult cultured rat ventricular cardiomyocytes. CARDIOSCIENCE4: 21-24, 1993.

56.       Canossa M., Ventura C., Vaona I., Carboni L., Guarnieri C., Spampinato S.: Prodynorphin mRNA expression in adult cultured rat ventricular cardiac myocytes. Biochim. Biophys. Acta 1172: 247-250, 1993.

57.       Finelli C., Guarnieri C., Muscari C., Ventura C., Caldarera C.M.: Incorporation of (14C)hypoxanthine into cardiac adenine nucleotides: effects of aging and post-ischemic reperfusion. Biochim. Biophys. Acta1180: 262-266, 1993.

58.       Ventura C., Spampinato S., Vaona I., Guarnieri C., Caldarera C.M.: Membrane depolarization modulates opioid gene expression in adult cultured myocytes. J. Mol. Cell. Cardiol. 25(1): S 64, 1993.

59.       Ventura C., Ferroni C., Flamigni F., Stefanelli C., Capogrossi M.C.: Polyamine effects on [Ca2+]ihomeostasis and contractility in isolated rat ventricular cardiomyocytes. Am. J. Physiol.267: H587-H592, 1994.

60.       Ventura C., Guarnieri C., Vaona I., Campana G., Pintus G., Spampinato S.: Dynorphin gene expression and release in the myocardial cell. J. Biol. Chem. 269: 5384-5386, 1994.

61.       Ventura C., Pintus G., Vaona I., Bennardini F., Pinna G., Tadolini B.: Phorbol ester regulation of opioid peptide gene expression in myocardial cells: Role of nuclear protein kinase C. J. Biol. Chem.270: 30115-30120, 1995.

62.       Ventura C., Pintus G., Fiori M.G., Bennardini F., Pinna G., Gaspa L.: Opioid peptide gene expression in the primary hereditary cardiomyopathy of the Syrian hamster. Part I: Regulation of prodynorphin gene expression by nuclear protein kinase C. J. Biol. Chem.272: 6685-6692, 1997.

63.       Ventura C., Pintus G., Tadolini B.: Opioid peptide gene expression in the primary hereditary cardiomyopathy of the Syrian hamster. Part II: Role of intracellular calcium loading. J. Biol. Chem.272: 6693-6698, 1997.

64.       Ventura C., Pintus G.: Opioid peptide gene expression in the primary hereditary cardiomyopathy of the Syrian hamster. Part III: Autocrine stimulation of prodynorphin gene expression by dynorphin B. J. Biol. Chem.272: 6699-6705, 1997.

65.       Nigro V., Okazaky Y., Belsito A., Piluso G., Matsuda Y., Politano L., Nigro G., Ventura C., Abbondanza C., Molinari A.M., Acampora D., Nishimura M., Hayashizaki Y., Puca G.A.: Identification of the Syrian hamster cardiomyopathy gene. Human Molecular Genetics6: 601-607, 1997.

66.       Pintus G., Tadolini B., Maioli M., Posadino A.M., Bennardini F., Bettuzzi S., Ventura C.: Heparin inhibits phorbol ester-induced ornithine decarboxylase gene expression in endothelial cells. FEBS Letters423: 98-104, 1998.

67.       Ventura C., Pintus G., Tadolini B.: Opioid peptide gene expression in the myocardial cell. Trends in Cardiovascular Medicine8, 102-110, 1998.

68.       Ventura C., Maioli M., Pintus G., Posadino A.M., Tadolini B.: Nuclear opioid receptors activate opioid peptide gene transcription in isolated myocardial nuclei. J. Biol. Chem.273: 13383-13386, 1998.

69.       Pintus G., Tadolini B., Maioli M., Posadino A.M., Gaspa L., Ventura C. Heparin down-regulates phorbol ester-induced protein kinase c (PKC) gene expression in human endothelial cells: enzyme-mediated autoregulation of PKC-a and-d genes. FEBS Letters 449: 135-140, 1999.

70.       Ventura C., Pintus G., Maioli M. Sarcoplasmic reticulum Ca2+-ATPase gene expression to the rescue of myocardial contractility in hypothyroid associated heart failure. Cardiovasc. Res.43: 282-284, 1999.

71.       Ventura C., Maioli M., Pintus G., Gottardi G., Bersani F. Elf-pulsed magnetic fields modulate opioid peptide gene expression in myocardial cells. Cardiovasc. Res.45: 1054-1064, 2000.

72.       Ventura C., Maioli M. Opioid peptide gene expression primes cardiogenesis in embryonal pluripotent stem cells. Circ. Res.87:189-194, 2000.

73.       Ventura C.Maioli M. PKC control of gene expression. Critical Reviews in Eukaryotic Gene Expression, 11:243-267, 2001.

74.       Sanna B., Debidda M., Pintus G., Tadolini B., Posadino A.M., Bennardini F., Sava G., Ventura C. The anti-metastatic agent imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate induces endothelial cell apoptosis by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway. Arch. Biochem. Biophys. 403:209-218, 2002.

75.       Pintus G., Tadolini B., PosadinoA., Sanna B., Debidda B., Bennardini F., Sava G., VenturaC.Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cells proliferation. Eur. J. Biochem.269:5861-5870, 2002.

76.       VenturaC., Zinellu E., Maninchedda E., Fadda M., Maioli M. Protein kinase C signaling transduces endorphin-primed cardiogenesis in GTR1 embryonic stem cells. Circ. Res.92:617-622, 2003.

77.       VenturaC., Zinellu E., Maninchedda E., Fadda M., Maioli M. Protein kinase C signaling transduces endorphin-primed cardiogenesis in GTR1 embryonic stem cells. Circ. Res. online supplement, 92:1-20, 2003.

78.       VenturaC., Zinellu E., Maninchedda E., Maioli M. Dynorphin B is an agonist of nuclear opioid receptors coupling nuclear protein kinase c activation to the transcription of cardiogenic genes in GTR1 embryonic stem cells. Circ. Res.92: 623-629, 2003.

79.       VenturaC., Zinellu E., Maninchedda E., Maioli M. Dynorphin B is an agonist of nuclear opioid receptors coupling nuclear protein kinase c activation to the transcription of cardiogenic genes in GTR1 embryonic stem cells. Circ. Res., online supplement, 92:1-7, 2003.

80.       Debidda M., Sanna B., Cossu A., Posadino A.M., Tadolini B., Ventura C., Pintus G. NAMI-A inhibits the PMA-induced ODC gene expression in ECV304 cells: involvement of PKC/Raf/Mek/ERK signalling pathway. Int. J. Oncol. 23: 477-482, 2003.

81.       Pintus G., Tadolini B., Posadino A.M., Sanna B., Debidda M., Carru C., Deiana L., Ventura C. PKC/Raf/MEK/ERK signaling pathway modulates native-LDL-induced E2F-1 gene expression and endothelial cell proliferation. Cardiovasc. Res.59:934-944, 2003.

82.       Newman  J.H., Trembath  R.C., Morse J.A., Grunig E., Loyd J.E., Adnot S., Coccolo F., Ventura C., Phillips III J.A., Knowles J.A., Janssen B., Eickelberg O., Eddahibi, S., Herve P., Nichols W.C., Elliott G. Genetic Basis of Pulmonary Arterial Hypertension Current Understanding and Future Directions. J. Am. Coll. Cardiol.43:33S–39S, 2004.

83.       Ventura C., Maioli M., Asara Y., Santoni D., Scarlata I., Cantoni S., Perbellini A. Butyric and retinoic mixed ester of hyaluronan: A novel differentiating glycoconjugate affording a high-throughput of cardiogenesis in embryonic stem cells. J. Biol. Chem.279:23574-23579, 2004.

84.       Ventura C., Maioli M., Asara Y., Santoni D., Mesirca P., Remondini D., Bersani F. Turning on stem cell cardiogenesis with extremely low frequency magnetic fields. The FASEB Journal express article 10.1096/fj.04-2695fje. Published online October 26, 2004.

85.       Ventura C., Maioli M., Asara Y., Santoni D, Mesirca P., Remondini D., Bersani F. Turning on stem cell cardiogenesis with extremely low frequency magnetic fields. FASEB J. 19:155-157, 2005.

86.       Ventura C.Forced myocardin expression primes cardiac and smooth muscle transcription patterning in human mesenchymal stem cells. Cardiovasc. Res.67:182-183, 2005.

87.       Ventura C.CAM and cell fate targeting: molecular and energetic insights into cell growth and differentiation. Evid. Based Complement. Alternat. Med.2:277-283, 2005.

88.       Ventura C., Branzi A. Autocrine and intracrine signaling for cardiogenesis in embryonic stem cells: a clue for the development of novel differentiating agents. Handb. Exp. Pharmacol.174:123-146, 2006.

89.       Ventura C., Cantoni S., Cavallini C. Stem Cells: a promise for cardiac repair. Organ Tissues and Cells9: 167-173, 2006.

90.       Alviano F., Fossati V., Marchionni C., Arpinati M., Bonsi L., Franchina M., Lanzoni G., Cantoni S., Cavallini C., Bianchi F., Tazzari P., Pasquinelli G., Foroni L., Ventura C.,Grossi A., Bagnara G. Term amniotic membrane is a high throughput source for multipotent mesenchymal stem cells with the ability to differentiate into endothelial cells in vitro. BMC Dev. Biol.7:11 doi:10.1186/1471-213X-7-11, 2007.

91.       Marini M., Lapalombella R., Margonato V., Ronchi R., Samaja M., Scapin C., Gorza L., Maraldi T., Carinci P., Ventura C.,Veicsteinas A. Mild exercise training, cardioprotection and stress genes profile.Eur. J. Appl. Physiol.99:503-510, 2007.

92.       Maioli M., Asara Y., Pintus A., Ninniri S., Bettuzzi S., Scaltriti M., Galimi F., Ventura C.Creating prodynorphin-expressing stemcells alerted for a high-throughput ofcardiogenic commitment. Regenerative Medicine 2:193-202, 2007.

93.       Ventura C.,Cantoni S., Bianchi F., Lionetti V., Cavallini C., Scarlata I., Foroni L., Maioli M., Bonsi L., Alviano F., Fossati V., Bagnara G.P., Pasquinelli G., Recchia F.A., Perbellini A. Hyaluronan mixed esters of butyric and retinoic acid drive cardiac and endothelial fate in term placenta human mesenchymal stem cells and enhance cardiac repair in infarcted rat hearts. J. Biol. Chem.282:14243-14252, 2007.

94.       Ventura, C.,Cavallini, C., Bianchi, F., Cantoni, S. Stem cells and cardiovascular repair: a role for natural and synthetic molecules harboring differentiating and paracrine logics. Cardiovasc. Hematol. Agents Med. Chem.6:60-68, 2008.

95.       Ventura, C.,Cantoni, S., Bianchi, F., Cavallini, C. Paracrine, Autocrine and Intracrine Patterning for Cardiovascular Repair with Human Mesenchymal Stem Cells: Role of New Chemistry for Regenerative Medicine. In:  "Stem Cell Applications in Diseases", pp 261-282. NOVA Publishers, 2008, Editors: Mikkel L. Sorensen.

96.       Maioli, M., Pintus, A., Montella, A., Bandiera, P., Cantoni, S., Cavallini, C., Bianchi, F., Ventura, C.Hyaluronan mixed esters of butyric and retinoic acids drive smad gene expression and signaling during the cardiogenic commitment of mouse embryonic and human mesenchymal stem cells. J. Biol. Chem.2008, Submitted.