1) Analysis of the regulation and of the expression of genes
involved in the biosynthesis of polyphenols (stilbenes,
flavonoids, catechins, etc) in tissues and in cell cultures of
Vitis vinifera treated with different biotic and abiotic
elicitors. This research involves the use of modern proteomic, mass
spectrometry and Real-Time PCR techniques and the
collaboration with several research groups at local, national and
2) The regulation of polyamine metabolism in different in vitro
and in vivo plant systems, and in plant-derived foodstuffs.
3) Chemical and enzymatic digestions and chromatographic
techniques applied to the extraction and analysis of high added
value bioactive molecules (protein/peptides, polyphenols, sugars,
fibers, etc) from agro-industrial food by-products and wastes (e.g.
grape pomace, rice, etc). Bioactivity determination
(antioxidant, anti-hypertensive, etc) of plant-derived
phytochemicals by in vitro tests in view of their biotechnological
(cosmetic, nutraceutical, fodd/feed, bioplastics) applications.