Foto del docente

Alessandra Bisi

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: CHEM-07/A Pharmaceutical Chemistry

Publications

F. Belluti; L. Piazzi; A. Bisi; S. Gobbi; M. Bartolini; A. Cavalli; P. Valenti; A. Rampa, Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2009, 44, pp. 1341 - 1348 [Scientific article]

S. Rizzo; A. Cavalli; L. Ceccarini; M. Bartolini; F. Belluti; A. Bisi; V. Andrisano; M. Recanatini; A. Rampa, Structure-Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine, «CHEMMEDCHEM», 2009, 4, pp. 670 - 679 [Scientific article]

S. Rizzo; C. Riviere; L. Piazzi; A. Bisi; S. Gobbi; M. Bartolini; V. Andrisano; F. Morroni; A. Tarozzi; J. P. Monti; A. Rampa, Benzofuran-Based Hybrid Compounds for the Inhibition of Cholinesterase Activity, Abeta Amyloid Aggregation, and Abeta Neurotoxicity, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 2883 - 2886 [Scientific article]

Gobbi S.; Cavalli A.; Bisi A.; Recanatini M., From nonsteroidal aromatase inhibitors to multifunctional drug candidates: classic and innovative strategies for the treatment of breast cancer., «CURRENT TOPICS IN MEDICINAL CHEMISTRY», 2008, 8, pp. 869 - 887 [Scientific article]

A. Bisi; M. Meli; S. Gobbi; A. Rampa; M. Tolomeo; L. Dusonchet, Multidrug resistance reverting activity and antitumor profile of new phenothiazine derivatives, «BIOORGANIC & MEDICINAL CHEMISTRY», 2008, 16, pp. 6474 - 6482 [Scientific article]

S. Lucas; R. Heim; M. Negri; I. Antes; C. Ries; K. E. Schewe; A. Bisi; S. Gobbi; R; W. Hartmann, Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 6138 - 6149 [Scientific article]

Barbera M.; Caputo A.; Zampiron A.; Gobbi S.; Rampa A.; Bisi A.; Carrara M., The ability of coumarin-, flavanon- and flavonol-analogues of flavone acetic acid to stimulate human monocytes., «ONCOLOGY REPORTS», 2008, 19, pp. 187 - 196 [Scientific article]

L. Piazzi; F. Belluti; A. Bisi; S. Gobbi; S. Rizzo; M. Bartolini; V. Andrisano; M. Recanatini; A. Rampa, CHOLINESTERASE INHIBITORS: SAR AND ENZYME INHIBITORY ACTIVITY OF 3-[omega-(BENZYLMETHYLAMINO)ALKOXY]XANTHEN-9-ONES, «BIOORGANIC & MEDICINAL CHEMISTRY», 2007, 15, pp. 575 - 585 [Scientific article]

Piazzi L.; Cavalli A.; Belluti F.; Bisi A.; Gobbi S.; Rizzo S.; Bartolini M.; Andrisano V.; Recanatini M.; Rampa A., Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives., «JOURNAL OF MEDICINAL CHEMISTRY», 2007, 50, pp. 4250 - 4254 [Scientific article]

Gobbi S.; Cavalli A.; Negri M.; Schewe K.E.; Belluti F.; Piazzi L.; Hartmann R.W.; Recanatini M.; Bisi A., Imidazolylmethylbenzophenones as highly potent aromatase inhibitors., «JOURNAL OF MEDICINAL CHEMISTRY», 2007, 50, pp. 3420 - 3422 [Scientific article]

Gobbi S.; Cavalli A.; Rampa A.; Belluti F.; Piazzi L.; Paluszcak A.; Hartmann R.W.; Recanatini M.; Bisi A., Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme, «JOURNAL OF MEDICINAL CHEMISTRY», 2006, 49, pp. 4777 - 4780 [Scientific article]

Gobbi S.; Belluti F.; Bisi A.; Piazzi L.; Rampa A.; Zampiron A.; Barbera M.; Caputo A.; Carrara M., New derivatives of xanthenone-4-acetic acid: synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells, «BIOORGANIC & MEDICINAL CHEMISTRY», 2006, 14, pp. 4101 - 4109 [Scientific article]

Bisi A.; Gobbi S.; Rampa A.; Belluti F.; Piazzi L.; Valenti P.; Gyemant N.; Molnar J., New potent P-glycoprotein inhibitors carrying a polycyclic scaffold, «JOURNAL OF MEDICINAL CHEMISTRY», 2006, 49, pp. 3049 - 3051 [Scientific article]

Belluti F.; Rampa A.; Piazzi L.; Bisi A.; Gobbi S.; Bartolini M.; Andrisano V.; Cavalli A.; Recanatini M.; Valenti P., Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation., «JOURNAL OF MEDICINAL CHEMISTRY», 2005, 48, pp. 4444 - 4456 [Scientific article]

Cavalli A.; Bisi A.; Bertucci C.; Rosini C.; Paluszcak A.; Gobbi S.; Giorgio E.; Rampa A.; Belluti F.; Piazzi L.; Valenti P.; Hartmann R.W.; Recanatini M., Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach, «JOURNAL OF MEDICINAL CHEMISTRY», 2005, 48 (23), pp. 7282 - 7289 [Scientific article]