Bolognesi M.L.; Rosini M.; Andrisano V.; Bartolini M.; Minarini A.; Tumiatti V.; Melchiorre C., MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond, «CURRENT PHARMACEUTICAL DESIGN», 2009, 15, pp. 601 - 613 [articolo]
M. Rosini; M. Bartolini; E. Simoni; C. Gotti; D. McClymont; ML Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre, Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease, in: , «DRUGS OF THE FUTURE», 2009, 34, pp. 195 - 195 (atti di: Frontiers in medicinal chemistry: Emerging targets, novel candidates and innovative strategies, Barcelona, October, 4-6, 2009) [atti di convegno-abstract]
A. Minarini; V. Tumiatti; M.L. Bolognesi; M. Rosini; C. Melchiorre, Polymethylene tetraamine backbone as template for the development of biologically active polyamines, in: Biogenic amines: biochemical, physiological and clinical aspects, s.l, s.n, 2009, pp. 14 - 14 (atti di: Biogenic amines: biochemical, physiological and clinical aspects, Bertinoro (FC, Italy), 11-14, 2009) [atti di convegno-abstract]
Tumiatti V., A rational design of new multi-target-directed-ligands for the treatment of Alzheimer's disease, in: Mainzer Forums Medizinische Chemie, s.l, s.n, 2008, pp. 35 - 36 (atti di: 16th Mainzer Forum Medicinal Chemistry. Treatment strategies for dementia- a challenge of the 21st century, Mainz University (Germany), September 26th, 2008) [Contributo in Atti di convegno]
A. Minarini; G. Marucci; C. Bellucci; G. Giorgi; V. Tumiatti; M. L. Bolognesi; R. Matera; M. Rosini; C. Melchiorre, Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics, «BIOORGANIC & MEDICINAL CHEMISTRY», 2008, 16, pp. 7311 - 7320 [articolo]
M. L. Bolognesi; A. Minarini; M. Rosini; V. Tumiatti; C. Melchiorre, From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease, «MINI-REVIEWS IN MEDICINAL CHEMISTRY», 2008, 8, pp. 960 - 967 [articolo]
M. Rosini; E. Simoni; M. Bartolini; A. Cavalli; L. Ceccarini; N. Pascu; D. W. McClymont; A. Tarozzi; M. L. Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre, Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 4381 - 4384 [articolo]
A. Cavalli; M. L. Bolognesi; A. Minarini; M.Rosini; V. Tumiatti; M. Recanatini; C. Melchiorre, Multi-target-Directed Ligands To Combat Neurodegenerative Diseases, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 347 - 372 [articolo]
Gasperi-Campani A.; Baiocchi D.; Roncuzzi L.; Gilli E.; Milelli A.; Tumiatti V., NEWLY SYNTHESIZED POLYAMINE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS, in: , «EUROPEAN JOURNAL OF CANCER», 2008, 6 (9), pp. 88 - 88 (atti di: 20th meeting of the European Association for Cancer Research, Lyon, France, 5-8. 07. 2008) [atti di convegno-abstract]
V. Tumiatti; M. L. Bolognesi; A. Minarini; M. Rosini; A. Milelli; R. Matera; C. Melchiorre, Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update, «EXPERT OPINION ON THERAPEUTIC PATENTS», 2008, 18, pp. 387 - 401 [articolo]
V. Tumiatti; A. Milelli; A. Minarini; M. Rosini; M. L. Bolognesi; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; C. Melchiorre, Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer., «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 7308 - 7312 [articolo]
V. Tumiatti; A. Milelli; A. Minarini; M. L. Bolognesi; M. Rosini; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; F. Colizzi; C. Melchiorre, Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone, in: Atti del XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, s.l, s.n, 2008, pp. 207 - 207 (atti di: XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, Palermo, 18-21 Maggio 2008) [atti di convegno-abstract]
Melchiorre C.; Antonello A.; Banzi R.; Bolognesi M.L.; Minarini A.; Rosini M.; Tumiatti V., Polymethylene tetraamine backbone as template for the development of biologically active polyamines, «MEDICINAL RESEARCH REVIEWS», 2003, 23, pp. 200 - 233 [articolo]
Rosini M.; Bixel M.G.; Marucci G.; Budriesi R.; Krauss M.; Bolognesi M.L.; Minarini A.; Tumiatti V.; Hucho F.; Melchiorre C., Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 2. Role of polymethylene chain lengths separating amine functions and of substituents on the terminal nitrogen atoms, «JOURNAL OF MEDICINAL CHEMISTRY», 2002, 45, pp. 1860 - 1878 [articolo]
Bolognesi M.L.; Bixel M.G.; Marucci G.; Bartolini M.; Krauss M.; Angeli P.; Antonello A.; Rosini M.; Tumiatti V.; Hucho F.; Melchiorre C., Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure, «JOURNAL OF MEDICINAL CHEMISTRY», 2002, 45, pp. 3286 - 3295 [articolo]
