Foto del docente

Silvia Gobbi

Professoressa associata

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHIM/08 CHIMICA FARMACEUTICA

Pubblicazioni

S. Rizzo; C. Riviere; L. Piazzi; A. Bisi; S. Gobbi; M. Bartolini; V. Andrisano; F. Morroni; A. Tarozzi; J. P. Monti; A. Rampa, Benzofuran-Based Hybrid Compounds for the Inhibition of Cholinesterase Activity, Abeta Amyloid Aggregation, and Abeta Neurotoxicity, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 2883 - 2886 [articolo]

Gobbi S.; Cavalli A.; Bisi A.; Recanatini M., From nonsteroidal aromatase inhibitors to multifunctional drug candidates: classic and innovative strategies for the treatment of breast cancer., «CURRENT TOPICS IN MEDICINAL CHEMISTRY», 2008, 8, pp. 869 - 887 [articolo]

S. Gobbi; A. Bisi; A. Cavalli; F. Belluti; L. Piazzi; A. Rampa; K. Schede; R. W. Hartmann, Imidazolylmethylxanthones as potent inhibitors of cytochrome P450 aromatase, in: XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, s.l, s.n, 2008, pp. 206 - 206 (atti di: XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, Palermo, 18-21 Maggio 2008) [atti di convegno-abstract]

A. Bisi; M. Meli; S. Gobbi; A. Rampa; M. Tolomeo; L. Dusonchet, Multidrug resistance reverting activity and antitumor profile of new phenothiazine derivatives, «BIOORGANIC & MEDICINAL CHEMISTRY», 2008, 16, pp. 6474 - 6482 [articolo]

S. Lucas; R. Heim; M. Negri; I. Antes; C. Ries; K. E. Schewe; A. Bisi; S. Gobbi; R; W. Hartmann, Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 6138 - 6149 [articolo]

Barbera M.; Caputo A.; Zampiron A.; Gobbi S.; Rampa A.; Bisi A.; Carrara M., The ability of coumarin-, flavanon- and flavonol-analogues of flavone acetic acid to stimulate human monocytes., «ONCOLOGY REPORTS», 2008, 19, pp. 187 - 196 [articolo]

Bisi A.; Meli M.; Gobbi S.; Rampa A.; Tolomeo M.; Dusonchet L., Antitumor profile of new phenothiazine derivatives, in: Frontiers in CNS and oncology medicinal chemistry, SIENA, s.n, 2007, pp. 35 - 35 (atti di: Frontiers in CNS and oncology medicinal chemistry, Siena, 7-9 ottobre 2007) [atti di convegno-abstract]

L. Piazzi; F. Belluti; A. Bisi; S. Gobbi; S. Rizzo; M. Bartolini; V. Andrisano; M. Recanatini; A. Rampa, CHOLINESTERASE INHIBITORS: SAR AND ENZYME INHIBITORY ACTIVITY OF 3-[omega-(BENZYLMETHYLAMINO)ALKOXY]XANTHEN-9-ONES, «BIOORGANIC & MEDICINAL CHEMISTRY», 2007, 15, pp. 575 - 585 [articolo]

Piazzi L.; Cavalli A.; Belluti F.; Bisi A.; Gobbi S.; Rizzo S.; Bartolini M.; Andrisano V.; Recanatini M.; Rampa A., Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives., «JOURNAL OF MEDICINAL CHEMISTRY», 2007, 50, pp. 4250 - 4254 [articolo]

Rampa A.; Belluti F.; Gobbi S.; Piazzi L.; Bartolini M.; Bisi A., Hybrid drugs for Alzheimer's disease: new indanone derivatives bearing a pharmacophoric fragment of AP2238, in: Frontiers in CNS and oncology medicinal chemistry, SIENA, s.n, 2007, pp. 49 - 50 (atti di: Frontiers in CNS and oncology medicinal chemistry, Siena, 7-9 ottobre 2007) [atti di convegno-abstract]

Gobbi S.; Cavalli A.; Negri M.; Schewe K.E.; Belluti F.; Piazzi L.; Hartmann R.W.; Recanatini M.; Bisi A., Imidazolylmethylbenzophenones as highly potent aromatase inhibitors., «JOURNAL OF MEDICINAL CHEMISTRY», 2007, 50, pp. 3420 - 3422 [articolo]

Gobbi S.; Bisi A.; Belluti F.; Piazzi L.; Rampa A.; Cavalli A.; Schede K.; Hartmann R.W., New potent inhibitors of cytochrome P450 aromatase, in: 16th Camerino-Noordwijkerhout Symposium-An overview of receptor chemistry, CAMERINO, s.n, 2007, pp. 113 - 113 (atti di: 16th Camerino-Noordwijkerhout Symposium, Camerino, 9-13 settembre 2007) [atti di convegno-abstract]

Gobbi S.; Cavalli A.; Rampa A.; Belluti F.; Piazzi L.; Paluszcak A.; Hartmann R.W.; Recanatini M.; Bisi A., Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme, «JOURNAL OF MEDICINAL CHEMISTRY», 2006, 49, pp. 4777 - 4780 [articolo]

Gobbi S.; Belluti F.; Bisi A.; Piazzi L.; Rampa A.; Zampiron A.; Barbera M.; Caputo A.; Carrara M., New derivatives of xanthenone-4-acetic acid: synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells, «BIOORGANIC & MEDICINAL CHEMISTRY», 2006, 14, pp. 4101 - 4109 [articolo]

Bisi A.; Gobbi S.; Rampa A.; Belluti F.; Piazzi L.; Valenti P.; Gyemant N.; Molnar J., New potent P-glycoprotein inhibitors carrying a polycyclic scaffold, «JOURNAL OF MEDICINAL CHEMISTRY», 2006, 49, pp. 3049 - 3051 [articolo]