Foto del docente

Silvia Gobbi

Professoressa associata

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHEM-07/A Chimica farmaceutica

Pubblicazioni

A. Rampa; M. Bartolini; A. Bisi; F. Belluti; S. Gobbi; V. Andrisano; A. Ligresti; V. Di Marzo, The first dual ChE/FAAH inhibitors: new perspectives for Alzheimer's disease?, «ACS MEDICINAL CHEMISTRY LETTERS», 2012, 3, pp. 182 - 186 [articolo]

S. Rizzo; A. Tarozzi; M. Bartolini; G. Da Costa; A. Bisi; S. Gobbi; F. Belluti; A. Ligresti; M. Allarà; J-P. Monti; V. Andrisano; V. Di Marzo; P. Hrelia; A. Rampa, 2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2012, 58, pp. 519 - 532 [articolo]

A. Rampa; F. Belluti; S. Gobbi; A. Bisi, Hybrid-Based Multi-Target Ligands for the Treatment of Alzheimer's Disease, «CURRENT TOPICS IN MEDICINAL CHEMISTRY», 2011, 11, pp. 2716 - 2730 [articolo]

S. Rizzo; A. Bisi; M. Bartolini; F. Mancini; F. Belluti; S. Gobbi; V. Andrisano; A. Rampa, Multi-target strategy to address Alzheimer’s disease: Design, synthesis and biological evaluation of new tacrine-based dimers, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2011, 46, pp. 4336 - 4343 [articolo]

Gobbi S.; Zimmer C.; Belluti F.; Rampa A.; Hartmann R.W.; Recanatini M.; Bisi A., Novel highly potent and selective nonsteroidal aromatase inhibitors: synthesis, biological evaluation and structure-activity relationships investigation, «JOURNAL OF MEDICINAL CHEMISTRY», 2010, 53, pp. 5347 - 5351 [articolo]

S. Rizzo; M. Bartolini; L. Ceccarini; L. Piazzi ; S. Gobbi; A. Cavalli; M. Recanatini; V. Andrisano; A. Rampa, Targeting Alzheimer’s disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238, «BIOORGANIC & MEDICINAL CHEMISTRY», 2010, 18, pp. 1749 - 1760 [articolo]

S. Bova; S. Saponara; A. Rampa; S. Gobbi; L. Cima; F. Fusi; G. Sgaragli; M. Cavalli; C. de los Rios; J. Striessnig; A. Bisi, Anthracene Based Compounds as New L-type Ca2+ Channel Blockers: Design, Synthesis, and Full Biological Profile, «JOURNAL OF MEDICINAL CHEMISTRY», 2009, 52, pp. 1259 - 1262 [articolo]

Lim H.D.; Istyastono E.P.; van de Stolpe A.; Romeo G.; Gobbi S.; Schepers M.; Lahaye R.; Menge W.M.; Zuiderveld O.P.; Jongejan A.; Smits R.A.; Bakker R.A.; Haaksma E.E.; Leurs R.; de Esch I.J., Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies., «BIOORGANIC & MEDICINAL CHEMISTRY», 2009, 17, pp. 3987 - 3994 [articolo]

F. Belluti; L. Piazzi; A. Bisi; S. Gobbi; M. Bartolini; A. Cavalli; P. Valenti; A. Rampa, Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2009, 44, pp. 1341 - 1348 [articolo]

Barbera M.; Kettunen M. I.; Caputo A.; Hu D. E.; Gobbi S.; Brindle K. M.; Carrara M., Immune-modulating and anti-vascular activities of two xanthenone acetic acid analogues: a comparative study to DMXAA., «INTERNATIONAL JOURNAL OF ONCOLOGY», 2009, 34, pp. 273 - 279 [articolo]

S. Rizzo; C. Riviere; L. Piazzi; A. Bisi; S. Gobbi; M. Bartolini; V. Andrisano; F. Morroni; A. Tarozzi; J. P. Monti; A. Rampa, Benzofuran-Based Hybrid Compounds for the Inhibition of Cholinesterase Activity, Abeta Amyloid Aggregation, and Abeta Neurotoxicity, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 2883 - 2886 [articolo]

Gobbi S.; Cavalli A.; Bisi A.; Recanatini M., From nonsteroidal aromatase inhibitors to multifunctional drug candidates: classic and innovative strategies for the treatment of breast cancer., «CURRENT TOPICS IN MEDICINAL CHEMISTRY», 2008, 8, pp. 869 - 887 [articolo]

S. Gobbi; A. Bisi; A. Cavalli; F. Belluti; L. Piazzi; A. Rampa; K. Schede; R. W. Hartmann, Imidazolylmethylxanthones as potent inhibitors of cytochrome P450 aromatase, in: XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, s.l, s.n, 2008, pp. 206 - 206 (atti di: XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, Palermo, 18-21 Maggio 2008) [atti di convegno-abstract]

A. Bisi; M. Meli; S. Gobbi; A. Rampa; M. Tolomeo; L. Dusonchet, Multidrug resistance reverting activity and antitumor profile of new phenothiazine derivatives, «BIOORGANIC & MEDICINAL CHEMISTRY», 2008, 16, pp. 6474 - 6482 [articolo]

S. Lucas; R. Heim; M. Negri; I. Antes; C. Ries; K. E. Schewe; A. Bisi; S. Gobbi; R; W. Hartmann, Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 6138 - 6149 [articolo]