Foto del docente

Piero Parchi

Associate Professor

Department of Experimental, Diagnostic and Specialty Medicine - DIMES

Academic discipline: MED/26 Neurology

Research

Keywords: DNA Polymorphism TSE Protein chemistry Neuropathology Neurodegeneration Proteomic Prion Biomarkers Rapidly progressive dementia Neurodegenerative dementias

1) Definition of the full spectrum of clinico-pathological phenotypes in human prion disease focusing on the identification and characterization of novel rare phenotypes

2) Study of the epidemiology of Creutzfeldt-Jakob in Italy through the molecular and pathological analysis of clusters

3) Development of new assays for the sensitive and specific diagnostic detection and strain typing of Creutzfeldt-Jakob disease

4) Study of the molecular basis of strain variation in human prion disease through the characterization of the physico-chemical properties of PrPSc

5) Definition and validation of new diagnostic protocols for the post-mortem diagnosis of neurodegenerative diseases

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