Foto del docente

Michela Rosini

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: CHIM/08 Pharmaceutical Chemistry


ML Bolognesi; M. Bartolini; F. Mancini; G. Chiriano; L. Ceccarini; M. Rosini; A. Milelli; V. Tumiatti; V. Andrisano; C. Melchiorre, Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities, in: Trekking through receptor chemistry, s.l, s.n, 2010, pp. 124 - 124 (atti di: 28th Camerino-Cyprus-Noordwijkerhout symposium, Camerino (MC), 16-20 maggio 2010) [Abstract]

Simoni E.; Bergamini C.; Fato R.; Tarozzi A.; Bains S.; Motterlini R.; Cavalli A.; Bolognesi M.L.; Minarini A.; Hrelia P.; Lenaz G.; Rosini M.; Melchiorre C., Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents., «JOURNAL OF MEDICINAL CHEMISTRY», 2010, 53, pp. 7264 - 7268 [Scientific article]

Melchiorre C; Bolognesi ML; Minarini A; Rosini M ; Tumiatti V, Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy, «JOURNAL OF MEDICINAL CHEMISTRY», 2010, 53, pp. 5906 - 5914 [Scientific article]

ML Bolognesi; M Rosini; A Minarini; V Tumiatti; A Cavalli; M Bartolini; V Andrisano; R Fato; C Bergamini; C Melchiorre, Rational design of multitarget-directed antioxidants: merging memoquin and lipocrine molecular frameworks, in: Final Program and Poster Abstractsfor the 11th International Geneva/Springfield Symposium on Advances in Alzheimer Therapy, s.l, s.n, 2010, pp. 93 - 93 (atti di: 11th International Geneva/Springfield Symposium on Advances in Alzheimer Therapy, Geneva, Switzerland, March, 24-27, 2010) [Abstract]

Minarini A.; Milelli A.; Tumiatti V.; Rosini M.; Bolognesi M.L.; Melchiorre C., Synthetic polyamines: an overview of their multiple biological activities., «AMINO ACIDS», 2010, 38, pp. 383 - 392 [Scientific article]

Tumiatti V.; Minarini A.; Bolognesi M.L.; Milelli A.; Rosini M.; Melchiorre C., Tacrine Derivatives and Alzheimer's Disease, «CURRENT MEDICINAL CHEMISTRY», 2010, 17, pp. 1825 - 1838 [Scientific article]

Bolognesi M.L.; Matera R.; Minarini A.; Rosini M.; Melchiorre C., Alzheimer's disease: new approaches to drug discovery., «CURRENT OPINION IN CHEMICAL BIOLOGY», 2009, 13, pp. 303 - 308 [Scientific article]

A. De Simone; M. Pistolozzi; M. Rosini; C. Melchiorre; C. Bertucci, Circular Dichroism: a Study of Reversible Binding HSA Binding of Lipocrine., in: Nuove Prospettive in Chimica Farmaceutica 3, 2009, pp. 3 - 3 (atti di: NPCF3, Castelvecchio Pascoli (LU), Italia, 13-14 Febbraio 2009) [Contribution to conference proceedings]

Bolognesi M.L.; Rosini M.; Andrisano V.; Bartolini M.; Minarini A.; Tumiatti V.; Melchiorre C., MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond, «CURRENT PHARMACEUTICAL DESIGN», 2009, 15, pp. 601 - 613 [Scientific article]

M. Rosini; M. Bartolini; E. Simoni; C. Gotti; D. McClymont; ML Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre, Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease, in: , «DRUGS OF THE FUTURE», 2009, 34, pp. 195 - 195 (atti di: Frontiers in medicinal chemistry: Emerging targets, novel candidates and innovative strategies, Barcelona, October, 4-6, 2009) [Abstract]

A. Minarini; V. Tumiatti; M.L. Bolognesi; M. Rosini; C. Melchiorre, Polymethylene tetraamine backbone as template for the development of biologically active polyamines, in: Biogenic amines: biochemical, physiological and clinical aspects, s.l, s.n, 2009, pp. 14 - 14 (atti di: Biogenic amines: biochemical, physiological and clinical aspects, Bertinoro (FC, Italy), 11-14, 2009) [Abstract]

Bolognesi ML; Bartolini M; Rosini M; Andrisano V; Melchiorre C., Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action, «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2009, 19, pp. 4312 - 4315 [Scientific article]

Bolognesi ML; Cavalli A; Bergamini C; Fato R; Lenaz G; Rosini M; Bartolini M; Andrisano V; Melchiorre C., Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks, «JOURNAL OF MEDICINAL CHEMISTRY», 2009, 52, pp. 7883 - 7886 [Scientific article]

A. Minarini; G. Marucci; C. Bellucci; G. Giorgi; V. Tumiatti; M. L. Bolognesi; R. Matera; M. Rosini; C. Melchiorre, Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics, «BIOORGANIC & MEDICINAL CHEMISTRY», 2008, 16, pp. 7311 - 7320 [Scientific article]

M. L. Bolognesi; A. Minarini; M. Rosini; V. Tumiatti; C. Melchiorre, From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease, «MINI-REVIEWS IN MEDICINAL CHEMISTRY», 2008, 8, pp. 960 - 967 [Scientific article]