Foto del docente

Michela Rosini

Professoressa associata

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHIM/08 CHIMICA FARMACEUTICA

Pubblicazioni

M. Rosini; E. Simoni; M. Bartolini; A. Cavalli; L. Ceccarini; N. Pascu; D. W. McClymont; A. Tarozzi; M. L. Bolognesi; A. Minarini; V. Tumiatti; V. Andrisano; I. R. Mellor; C. Melchiorre, Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 4381 - 4384 [articolo]

A. Cavalli; M. L. Bolognesi; A. Minarini; M.Rosini; V. Tumiatti; M. Recanatini; C. Melchiorre, Multi-target-Directed Ligands To Combat Neurodegenerative Diseases, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 347 - 372 [articolo]

V. Tumiatti; M. L. Bolognesi; A. Minarini; M. Rosini; A. Milelli; R. Matera; C. Melchiorre, Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update, «EXPERT OPINION ON THERAPEUTIC PATENTS», 2008, 18, pp. 387 - 401 [articolo]

V. Tumiatti; A. Milelli; A. Minarini; M. Rosini; M. L. Bolognesi; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; C. Melchiorre, Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer., «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 7308 - 7312 [articolo]

V. Tumiatti; A. Milelli; A. Minarini; M. L. Bolognesi; M. Rosini; M. Micco; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; F. Colizzi; C. Melchiorre, Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone, in: Atti del XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, s.l, s.n, 2008, pp. 207 - 207 (atti di: XIII Meeting Strutture eterocicliche nella ricerca farmaceutica, Palermo, 18-21 Maggio 2008) [atti di convegno-abstract]

ML. Bolognesi; A. Minarini; M. Bartolini; A. Cavalli; F. Mancini; V. Andrisano; M. Rosini; V. Tumiatti; C. Melchiorre, Synthesis of monomeric derivatives to probe Memoquin bivalent interactions, in: Book of Abstracts, s.l, s.n, 2008, pp. 226 - 226 (atti di: XIX National Meeting on Medicinal Chemistry, Verona, 14-18 September 2008) [atti di convegno-abstract]

Bolognesi ML; Cavalli A; Valgimigli L; Bartolini M; Rosini M; Andrisano V; Recanatini M; Melchiorre C, Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer's Disease, «JOURNAL OF MEDICINAL CHEMISTRY», 2007, 50, pp. 6446 - 6449 [articolo]

Rosini M; Simoni E; Bolognesi ML; Andrisano V; Bartolini M; Tarozzi a; Hrelia P; Mellor I; Melchiorre C., Multitarget-directed drug design strategy: novel hybrid compounds between lipocrine and carvedilol, in: Programme and Abstracts 16th Camerino-Noordwijkrhout symposium "An overview of receptor chemistry, s.l, s.n, 2007, pp. 83 - 83 (atti di: 16th Camerino-Noordwijkrhout symposium "An overview of receptor chemistry, Camerino, September 9-13, 2007) [Contributo in Atti di convegno]

Matera R; Minarini A; Rosini M; Andrisano V; Mancini F; Melchiorre C., New quinazoline compounds as non-peptidomimetic BACE-1 inhibitors in the treatment of Alzheimer's disease, in: Programme and abstracts 16th Camerino-Noordwijkrhout symposium "An overview of receptor chemistry", s.l, s.n, 2007, pp. 115 - 115 (atti di: 16th Camerino-Noordwijkrhout symposium "An overview of receptor chemistry", Camerino, September 9-13, 2007) [Contributo in Atti di convegno]

Bolognesi ML; Banzi R; Bartolini M; Cavalli A; Tarozzi A; Andrisano V; Minarini A; Rosini M; Tumiatti V; Bergamini C; Fato R; Lenaz G; Hrelia P; Cattaneo A; Recanatini M; Melchiorre C., Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease, «JOURNAL OF MEDICINAL CHEMISTRY», 2007, 50, pp. 4882 - 4897 [articolo]

V. Tumiatti; A. Milelli; A. Minarini; M. L. Bolognesi; M. Rosini; V. Andrisano; M. Bartolini; F. Mancini; M. Recanatini; A. Cavalli; F. Colizzi; C. Melchiorre, Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer, in: Atti del Convegno XVIII Convegno nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana, s.l, s.n, 2007, pp. 32 - 32 (atti di: XVIII Convegno nazionale della Divisione di Chimica Farmaceutica della Società Chimica Italiana, Chieti-Pescara, 16-20 Settembre 2007) [Contributo in Atti di convegno]

Rosini M; Bolognesi ML; Giardina D; Minarini A; Tumiatti V; Melchiorre C., Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents., «CURRENT TOPICS IN MEDICINAL CHEMISTRY», 2007, 7, pp. 147 - 162 [articolo]

Pistolozzi M.; Rosini M.; Melchiorre C.; Bertucci C., Reversible HSA binding of lipocrine: a circular dichroism study., in: Frontiers in CNS and Oncology Medicinal Chemistry-Program and Abstracts, s.l, s.n, 2007, pp. 54 - 54 (atti di: Frontiers in CNS and Oncology Medicinal Chemistry, Siena-Italy, October 7-9, 2007) [atti di convegno-abstract]

V. Tumiatti; A. Minarini; A. Milelli; M. Rosini; M. Buccioni; G. Marucci; C. Ghelardini; C. Bellucci; C. Melchiorre, Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties, «BIOORGANIC & MEDICINAL CHEMISTRY», 2007, 15, pp. 2312 - 2321 [articolo]

M. Rosini; F. Mancini; A. Tarozzi; F. Colizzi; V. Andrisano; M.L. Bolognesi; P. Hrelia; C. Melchiorre., Design, synthesis, and biological evaluation of substituted 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamine related compounds as fructose-1,6-bisphosphatase inhibitors, «BIOORGANIC & MEDICINAL CHEMISTRY», 2006, 14, pp. 7846 - 7853 [articolo]