Keywords:
IASP collection, fNMR
psychological assessment
somatization, psychophysiological aspects
Fibromyalgic Syndrome, Chronic Pain
Intestinal chronic inflammatory diseases
1) Evaluation of psychological status and psychophysiological
mechanisms of somatization in chronic intestinal inflammatory
disease patients with IASP collection as emotional activator, heart
frequency, intestinal permeability and SNC ( amygdala ) with fRNM.
2) Medical, psychological and psychophysiological aspects of
patients with benign chronic pain ( Fibromyalgic Syndrome, Urethral
Syndrome, Pelvic-perineal Syndrome, IBS, VVS...)
3) Evaluation of the attitudes toward Euthanasia and Physician-
Assisted Suicide and the prevention of burn-out risk in italian
primary care physicians.
4) Evaluation of Attachment style, alexitymia and
psychopathological features in GERD ( gastro-esophageal reflux
disease) patients.
5) Physical rehabilitation and burn-out: different aspects of the
syndrome and comparisons between healthcare professionals
involved.
1) Our research is articulated in two levels: (A) 800 IBD patients
( Crohn Disease and Ulcerative Colitis ), will be studied with a
psychological assessement ( SCL 90-R, TAS 20, PBI, PSQ, ASQ); (B)
in a smaller group of patients and controls we would evaluate
the intestinal permeability and the activation of Limbic Centers (
amigdala and anterior cingulate cortex ), during an emotional
activation by IASP Collection pictures. We will evaluate in plasma
before and after stress citokines Il1, Il6, TNT and PCR, Cortisol
and Substance P. Our data will allow a correlation of anxiety and
depression with immunocite activity, intestinal parietal
permeability and the activity of the flogosis.
2) Our research is aimed to study patients affected by
Fibromyalgic Syndrome and normal controls, evaluated from a
psychological ( IBQ, SQ, QUID, Emotional Involvement) and a
physiological point of view ( EMG, ECG ) in a baseline period and
during and after laboratory stressors ( Stroop Test, Mental
Arithmetic, Dichotomic Listening ). We expect a higher EMG basal
activity, a greater reactivity to psychological
stressors and a longer muscular activity during the
whole extinction period in patients toward controls.