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Maurizio Brigotti

Associate Professor

Department of Experimental, Diagnostic and Specialty Medicine - DIMES

Academic discipline: MED/04 Experimental Medicine and Pathophysiology

Publications

PUBBLICAZIONI SU RIVISTE SCIENTIFICHE INTERNAZIONALI

di Maurizio Brigotti

(Impact Factor 2020)

  1. Rambelli F., Brigotti M., Sperti S. & Montanaro L. (1987) "Interaction of diphtheria toxin fragment A and elongation factor 2 with Cibacron Blue" Biosci. Rep. 7, 737-743 (I.F. 3.840, Q3 Biochemistry and Molecular Biology)
  2. Brigotti M., Rambelli F., Zamboni M., Montanaro L. & Sperti S. (1989) "Effect of alpha-sarcin and ribosome-inactivating proteins on the interaction of elongation factor with ribosomes" Biochem. J. 257, 723-727 (I.F. 3.857, Q3 Biochemistry and Molecular Biology)
  3. Rambelli F., Brigotti M., Zamboni M., Denaro M., Montanaro L. & Sperti S. (1989) "Effect of the antibiotic purpuromycin on cell-free protein synthesizing systems" Biochem. J. 259, 307-310 (I.F. 3.857, Q3 Biochemistry and Molecular Biology)
  4. Zamboni M., Brigotti M., Rambelli F., Montanaro L. & Sperti S. (1989) "High pressure liquid chromatographic and fluorimetric methods for the determination of adenine released from ribosomes by ricin and gelonin" Biochem. J. 259, 639-643 (I.F. 3.857, Q3 Biochemistry and Molecular Biology)
  5. Sperti S., Zamboni M., Brigotti M., Rambelli F. & Montanaro L. (1989) "Alpha-sarcin impairs the N-glycosidase activity of ricin on ribosomes" Biochem. Biophys. Res. Commun. 160, 857-861 (I.F. 3.575, Q2 Biophysics)
  6. Brigotti M., Rambelli F., Nanetti A., Zamboni M., Sperti S. & Montanaro L. (1990) "Isolation of an inhibitor of cell-free protein synthesis from Salmonella enteritidis" Microbiologica 13, 55-60 (I.F. 2.479, Q3 Microbiology)
  7. Sperti S., Brigotti M., Zamboni M., Carnicelli D. & Montanaro L. (1991) "Requirements for the inactivation of ribosomes by gelonin" Biochem. J. 277, 281-284 (I.F. 3.857, Q3 Biochemistry and Molecular Biology)
  8. Zamboni M., Brigotti M., Montanaro L. & Sperti S. (1991) "Elongation factor 2 from Artemia salina embryos and its affinity for ribosomes" Eur. J. Biochem. (FEBS Journal) 200, 13-18 (I.F. 5.542, Q1 Biochemistry and Molecular Biology)
  9. Carnicelli D., Brigotti M., Montanaro L. & Sperti S. (1992) "Differential requirement of ATP and extra-ribosomal proteins for ribosome inactivation by eight RNA N-glycosidases" Biochem. Biophys. Res. Commun. 182, 579-582 (I.F. 3.575, Q2 Biophysics)
  10. Brigotti M., Sperti S., Carnicelli D. & Montanaro L. (1992) "Ribosome-bound elongation factor 2 escapes phosphorylation by Ca2+/calmodulin-dependent protein kinase III" Ital. J. Biochem. 41, 195-199 (I.F. 0.083; 2000)
  11. Brigotti M., Nanetti A., Montanaro L. & Sperti S. (1993) "Inactivation of ribosomes by an inhibitor of protein synthesis from Salmonella enteritidis" Microbiologica 16, 79-82 (I.F. 2.479, Q3 Microbiology)
  12. Brigotti M., Sperti S., Carnicelli D. & Montanaro L. (1993) "Partial purification of two proteins which sensitize ribosomes to gelonin: sensitization is not linked to phosphorylation of ribosomal proteins" Toxicon 31, 989-996 (I.F. 3.033, Q3 Toxicology)
  13. Brigotti M., Lorenzetti R., Carnicelli D., Sperti S. & Montanaro L. (1993) "Oligonucleotides complementary to the alpha-sarcin domain of 28S rRNA inhibit cell-free protein synthesis" Biochem. Mol. Biol. Int. (IUBMB Life) 31, 897-903 (I.F. 3.885, Q2 Biochemistry and Molecular Biology)
  14. Brigotti M., Carnicelli D., Sperti S. & Montanaro L. (1994) "RNA present in post-ribosomal supernatants makes ribosomes susceptible to inactivation by gelonin and alpha-sarcin" Biochem. Mol. Biol. Int. (IUBMB Life) 32, 585-596 (I.F. 3.885, Q2 Biochemistry and Molecular Biology)
  15. Brigotti M., Carnicelli D., Alvergna P., Pallanca A., Lorenzetti R., Denaro M., Sperti S. & Montanaro L. (1995) "3'-Immature tRNATrp is required for ribosome inactivation by gelonin, a plant RNA N-glycosidase" Biochem. J. 310, 249-253 (I.F. 3.857, Q3 Biochemistry and Molecular Biology)
  16. Brigotti M., Carnicelli D., Alvergna P., Pallanca A., Sperti S. & Montanaro L. (1995) "Differential up-regulation by tRNAs of ribosome inactivating proteins" FEBS Lett. 373, 115-118 (I.F. 4.124, Q1 Biophysics)
  17. Brigotti M., Carnicelli D., Alvergna P., Pallanca A., Sperti S. & Montanaro L. (1996) "tRNATrp as cofactor of gelonin, a ribosome-inactivating protein with RNA-N-glycosidase activity: features required for the cofactor activity" Biochem. Mol. Biol. Int. (IUBMB Life) 40, 181-188 (I.F. 3.885, Q2 Biochemistry and Molecular Biology)
  18. Carnicelli D., Brigotti M., Alvergna P., Pallanca A., Sperti S. & Montanaro L. (1997) "Cofactor requirement of ribosome-inactivating proteins from plants” J. Exp. Bot. 48, 1519-1523 (I.F. 6.992, Q1 Plant Sciences)
  19. Brigotti M., Carnicelli D., Alvergna P., Mazzaracchio R., Sperti S. & Montanaro L. (1997) "The RNA-N-glycosidase activity of Shiga-like toxin I: kinetic parameters of the native and activated toxin” Toxicon 35, 1431-1437 (I.F. 3.033, Q3 Toxicology)
  20. Pallanca A. Mazzaracchio R., Brigotti M., Carnicelli D., Alvergna P., Sperti S. & Montanaro L. (1998) "Uncompetitive inhibition by adenine of the RNA-N-glycosidase activity of ribosome-inactivating proteins" Biochim. Biophys. Acta – Protein Structure and Molecular Enzymology (Proteins and Proteomics) 1384, 277-284 (I.F. 3.036, Q2 Biophysics)
  21. Brigotti M., Keith G., Pallanca A., Carnicelli D., Alvergna P., Dirheimer G., Montanaro L. & Sperti S. (1998) "Identification of the tRNAs which up-regulate agrostin, barley RIP and PAP-S, three ribosome inactivating proteins of plant origin" FEBS Lett. 431, 259-262 (I.F. 4.124, Q1 Biophysics)
  22. Barbieri L., Valbonesi P., Brigotti M., Montanaro L., Stirpe F. & Sperti S. (1998) "Shiga-like toxin I is a polynucleotide:adenosine glycosidase" Mol. Microbiol. 29, 661-662 (I.F. 3.501, Q2 Microbiology)
  23. Brigotti M., Barbieri L., Valbonesi P., Stirpe F., Montanaro L. & Sperti S. (1998) "A rapid and sensitive method to measure the enzymatic activity of ribosome-inactivating proteins" Nucleic Acids Res. 26, 4306-4307 (I.F. 16.971, Q1 Biochemistry and Molecular Biology)
  24. Brigotti M., Petronini P.G., Borghetti A.F., Guidotti G.G., Sperti S. & Montanaro L. (1998) "Primer tRNATrp of RSV-transformed or RAV-1-infected cells up-regulates the antiribosomal activity of gelonin" Biochimie 80, 575-578 (I.F. 4.079, Q2 Biochemistry and Molecular Biology)
  25. Montanaro L., Arciola C.R., Borsetti E., Brigotti M. & Baldassarri L. (1998) "A polymerase chain reaction (PCR) method for the identification of collagen adhesin gene (cna) in Staphylococcus-induced prosthesis infections" Microbiologica 21, 359-363 (I.F. 2.479, Q3 Microbiology)
  26. Bonelli M.A., Alfieri R.R., Petronini P.G., Brigotti M., Campanini C. & Borghetti A.F. (1999) "Attenuated expression of 70-kDa heat-shock protein in WI-38 human fibroblasts during aging in vitro" Exp. Cell Res. 252, 20-32 (I.F. 3.905, Q3 Oncology)
  27. Brigotti M., Carnicelli D., Pallanca A., Rizzi S., Accorsi P., Montanaro L. & Sperti S. (1999) "Identity elements in bovine tRNATrp required for the specific stimulation of gelonin, a plant ribosome inactivating protein" RNA 5, 1357-1363 (I.F. 4.942, Q2 Biochemistry and Molecular Biology)
  28. Brigotti M., Carnicelli D., Accorsi P., Rizzi S., Montanaro L. & Sperti S. (2000) "4-Aminopyrazolo[3,4-d]pyrimidine (4-APP) as a novel inhibitor of the RNA and DNA depurination induced by Shiga toxin 1" Nucleic Acids Res. 28, 2383-2388 (I.F. 16.971, Q1 Biochemistry and Molecular Biology)
  29. Brigotti M., Rizzi S., Carnicelli D., Montanaro L. & Sperti S. (2000) "A survey of adenine and 4-aminopyrazolo[3,4-d]pyrimidine (4-APP) as inhibitors of ribosome-inactivating proteins (RIPs)” Life Sci. 68, 331-336 (I.F. 5.037, Q1 Pharmacology and Pharmacy)
  30. Brigotti M., Accorsi P., Carnicelli D., Rizzi S., González Vara A., Montanaro L. & Sperti S. (2001) "Shiga toxin 1: damage to DNA in vitro" Toxicon 39, 341-348 (I.F. 3.033, Q3 Toxicology)
  31. Carnicelli D., Brigotti M., Rizzi S., Keith G., Montanaro L. & Sperti S. (2001) “Nucleotides U28-A42 and A37 in unmodified yeast tRNATrp as negative identity elements for bovine tryptophanyl-tRNA synthetase” FEBS Lett. 492, 238-241 (I.F. 4.124, Q1 Biophysics)
  32. Brigotti M., Alfieri R., Sestili P., Bonelli M., Petronini P.G., Guidarelli A., Barbieri L., Stirpe F. & Sperti S. (2002) “Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells” FASEB J. 16, 365-372 (I.F. 5.191, Q1 Biology) Corresponding author
  33. Brigotti M., Petronini P.G., Carnicelli D., Alfieri R.R., Bonelli M.A., Borghetti A.F. & Wheeler K.P. (2003) “Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis” Biochem. J. 369, 369-374 (I.F. 3.857, Q3 Biochemistry and Molecular Biology)
  34. Barbieri L., Brigotti M., Perocco P., Carnicelli D., Ciani M., Mercatali L. & Stirpe F. (2003) “Ribosome-inactivating proteins depurinate poly(ADP-ribosyl)ated poly(ADP-ribose) polymerase and have transforming activity for 3T3 fibroblasts” FEBS Lett. 538, 178-182 (I.F. 3.057, Q2 Biophysics)
  35. Brigotti M., Carnicelli D. & González Vara A. (2004) “Shiga toxin 1 acting on DNA in vitro is a heat-stable enzyme not requiring proteolytic activation” Biochimie 86, 305-309 (I.F. 4.079, Q2 Biochemistry and Molecular Biology) Corresponding author
  36. Tazzari P.L., Ricci F., Carnicelli D., Caprioli A., Tozzi A.E., Rizzoni G., Conte R. & Brigotti M. (2004) “Flow cytometry detection of Shiga toxins in the blood from children with hemolytic uremic syndrome” Clinical Cytometry - Part B 61, 40-44 (I.F. 3.058, Q2 Medical Laboratory Technology) Corresponding author
  37. Sestili S., Alfieri R., Carnicelli D., Martinelli C., Barbieri L., Stirpe F., Bonelli M., Petronini P.G. & Brigotti M. (2005) “Shiga toxin 1 and ricin inhibit the repair of H2O2-induced DNA single strand breaks in cultured mammalian cells” DNA repair 4, 271-277 (I.F. 4.913, Q1 Toxicology)
  38. Brigotti M., Alfieri R., Petronini P.G. & Carnicelli D. (2006) “Inhibition by suramin of protein synthesis in vitro. Ribosomes as the target of the drug” Biochimie 88, 497-503 (I.F. 4.079, Q2 Biochemistry and Molecular Biology) Corresponding author
  39. Brigotti M., Caprioli A., Tozzi A.E., Tazzari P.L., Ricci F., Conte R., Carnicelli D., Procaccino M.A., Minelli F., Ferretti A.V.S., Paglialonga F., Edefonti A. & Rizzoni G. (2006) “Shiga toxins present in the gut and in the polymorphonuclear leukocytes circulating in the blood of children with hemolytic uremic syndrome” J. Clin. Microbiol. 44, 313-317 (I.F. 5.948 Q1 Microbiology) Corresponding author
  40. Caprioli A., Morabito S., Scheutz F., Chart H., Oswald E., Brigotti M., Monnens L., Aspan A., La Ragione R., Low C. & Newell D. (2006) “Pathogenesis of Verocytotoxin/Shiga toxins-producing Escherichia coli infection” [conference summary] Emerg. Infect. Dis. [serial on the Internet]. Vol. 12, available from http://www.cdc.gov/ncidod/EID/vol12no08/06-0170.htm (I.F. 6.883, Q1 Immunology)
  41. Montanaro L., Brigotti, M., Clohessy J., Barbieri S., Ceccarelli C., Santini D., Taffurelli M., Calienni M., Teruya-Feldstein J., Trerè D., Pandolfi P.P. & Derenzini M. (2006). “Dyskerin expression influences the level of ribosomal RNA pseudo-uridylation and telomerase RNA component in human breast cancer” J. Pathol. 210, 10-18 (I.F. 7.996, Q1 Pathology)
  42. Alfieri R.R., Bonelli M.A., Cavazzoni A., Brigotti M., Fumarola C., Sestili P., Mozzoni P., De Palma G., Mutti A., Carnicelli D., Vacondio F., Silva C., Borghetti A.F., Wheeler K.P. & Petronini P.G. (2006) “Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress” J. Physiol. London 576, 391-401 (I.F. 5.182, Q1 Physiology)
  43. Brigotti M., Carnicelli D., Ravanelli E., González Vara A., Martinelli C., Alfieri R.R., Petronini P.G. & Sestili P. (2007) “Molecular damage and induction of pro-inflammatory cytokines in human endothelial cells exposed to Shiga toxin 1, Shiga toxin 2 and a-sarcin. Infect. Immun. 75, 2201-2207 (I.F. 3.441, Q3 Infectious Diseases) Corresponding author
  44. Brigotti M., Carnicelli D., Ravanelli E., Barbieri S., Ricci F., Bontadini A., Tozzi A.E., Scavia G., Caprioli A. & Tazzari P.L. (2008) “Interactions between Shiga toxins and human polymorphonuclear leukocytes” J. Leukoc. Biol. 84, 1019-1027 (I.F. 4.962, Q2 Immunology) Corresponding author
  45. Brigotti M., Tazzari P.L., Ravanelli E., Carnicelli D., Barbieri S., Rocchi L., Arfilli V., Scavia G., Ricci F., Bontadini A., Alfieri R.R., Petronini P.G., Pecoraro C., Tozzi A.E. & Caprioli A. (2010) “Endothelial damage induced by Shiga toxins delivered by neutrophils during transmigration.” J. Leukoc. Biol. 88, 201-210 (I.F. 4.962, Q2 Immunology) Corresponding author
  46. Montanaro L., Calienni M., Bertoni S., Rocchi L., Sansone P., Storci G., Santini D., Ceccarelli C., Taffurelli M., Carnicelli D., Brigotti M., Bonafe M., Trere D. & Derenzini M. (2010) “Novel dyskerin-mediated mechanism of p53 inactivation through defective mRNA translation.” Cancer Res. 70, 4767-4777 (I.F. 12,701, Q1 Oncology)
  47. Arfilli V., Carnicelli D., Rocchi L., Ricci F., Pagliaro P., Tazzari P.L. & Brigotti M. (2010) “Shiga toxin 1 and ricin A chain bind to human polymorphonuclear leucocytes through a common receptor.” Biochem. J. 432, 173-180 (I.F. 3.857, Q3 Biochemistry and Molecular Biology) Corresponding author
  48. Brigotti M., Tazzari P.L., Ravanelli E., Carnicelli D., Rocchi L., Arfilli V., Scavia G., Minelli F., Ricci F., Pagliaro P., Ferretti V.S., Pecoraro C., Paglialonga F., Edefonti A., Procaccino M.A., Tozzi A.E. & Caprioli A. (2011) “Clinical relevance of Shiga toxin concentrations in the blood of patients with hemolytic uremic syndrome.” Pediatr. Infect. Dis. J. 30, 486-490 (I.F. 2.129, Q3 Pediatrics) Corresponding author
  49. Brigotti M., Carnicelli D., Arfilli V., Rocchi L., Ricci F., Pagliaro P., Tazzari P.L., González Vara A., Amelia M., Manoli F. & Monti S. (2011) “Change in conformation with reduction of a-helix content causes loss of neutrophil-binding activity in fully cytotoxic Shiga toxin 1.” J. Biol. Chem. 286, 34514-34521 (I.F. 5.157, Q2 Biochemistry and Molecular Biology) Corresponding author
  50. Brigotti M. (2012) “The interactions of human neutrophils with Shiga toxins and related plant toxins: danger or safety?” Toxins 4, 157-190 (I.F. 4.546, Q1 Toxicolgy) Corresponding author
  51. Fiume L., Vettraino M., Carnicelli D., Arfilli A., Di Stefano G. & Brigotti M. (2013) “Galloflavin prevents the binding of lactate dehydrogenase A to single stranded DNA and inhibits RNA synthesis in cultured cells.” Biochem. Biophys. Res. Commun. 430, 466-469 (I.F. 3.575, Q2 Biophysics)
  52. Rocchi L., Alfieri R.R., Petronini P.G., Montanaro L. & Brigotti M. (2013) “5’-Untranslated region of heat shock protein 70 mRNA drives translation under hypertonic conditions.” Biochem. Biophys. Res. Commun. 431, 321-325 (I.F. 3.575, Q2 Biophysics) Corresponding author
  53. Brigotti M., Arfilli V., Carnicelli D., Rocchi L., Calcabrini C., Ricci F., Pagliaro P., Tazzari P.L., Alfieri R.R., Petronini P.G. & Sestili P. (2013) “Shiga toxin 1, as DNA repair inhibitor, synergistically potentiates the activity of the anticancer drug, mafosfamide, on Raji cells.” Toxins 5, 431-444 (I.F. 4.546, Q1 Toxicology) Corresponding author
  54. Rocchi L., Pacilli A., Seti R., Penzo M., Schneider R.J., Treré D., Brigotti M. & Montanaro L. (2013) “Dyskerin depletion increases VEGF mRNA internal ribosomal entry site-mediated translation.” Nucleic Acids Res. 41, 8308- 8318 (I.F. 16.971, Q1 Biochemistry and Molecular Biology)
  55. Brigotti M., Carnicelli D., Arfilli V., Tamassia N., Borsetti F., Fabbri E., Tazzari P.L., Ricci F., Pagliaro P., Spisni E. & Cassatella M.A. (2013) “Identification of TLR4 as the receptor that recognizes Shiga toxins in human neutrophils.” J. Immunol. 191, 4748-4758 (I.F. 5.422, Q2 Immunology) Corresponding author
  56. Brigotti M. (2014) “Shiga toxins: the ribosome-inactivating proteins from pathogenic bacteria.” Chapter 7, pages 97-110. In Ribosome-inactivating Proteins: Ricin and related proteins, First Edition. Edited by Fiorenzo Stirpe and Douglas A. Lappi. Published by John Wiley & Sons, Inc. Corresponding author
  57. Penzo M., Rocchi L., Brugiere S., Carnicelli D., Onofrillo C., Couté Y. Brigotti M. & Montanaro L. (2015) “Human ribosomes from cells with reduced dyskerin levels are intrinsically altered in translation.” FASEB J. 29, 3472-3482 (I.F. 5.191, Q1 Biology) Co-corresponding author
  58. Lauria F., Tebaldi T., Lunelli L., Struffi P., Gatto P., Pugliese A., Brigotti M., Montanaro L., Ciribilli Y., Inga A., Quattrone A., Sanguinetti G. & Viero, G. (2015) “RiboAbacus: a model trained on polyribosome images predicts ribosome density and translational efficiency from mammalian transcriptomes.” Nucleic Acids Res. 43, e153 (I.F. 16.971, Q1 Biochemistry and Molecular Biology)
  59. He X., Quiñones B., Te Loo M., Loos S., Scavia G., Brigotti M., Levtchenko E. & Monnens L. (2015) “Serum Shiga toxin 2 values in patients during the acute phase of diarrhea-associated hemolytic uremic syndrome” Acta Paediatrica 104, e564-e568 (I.F. 2.299, Q2 Pediatrics)
  60. Arfilli V., Carnicelli D., Ardissino G., Torresani E., Scavia G. & Brigotti M. (2015) “A rapid and sensitive method to measure the functional activity of Shiga toxins in human serum” Toxins 7, 4564-4576 (I.F. 4.546, Q1 Toxicology) Corresponding author
  61. Ardissino G., Tel F., Possenti I., Testa S., Consonni D., Paglialonga F., Salardi S., Borsa-Ghiringhelli N., Salice P., Tedeschi S., Castorina P., Colombo R.M., Arghittu M., Daprai L., Monzani A., Tozzoli R., Brigotti M. & Torresani E. (2016) “Early volume expansion and outcomes of hemolytic uremic syndrome” Pediatrics 137, e20152153 (I.F. 7.124, Q1 Pediatrics)
  62. Carnicelli D., Arfilli V., Ricci F., Velati C., Tazzari P.L. & Brigotti M. (2016) “The antibiotic polymyxin B impairs the interactions between Shiga toxins and human neutrophils” J. Immunol. 196, 1177-1185 (I.F. 5.422, Q2 Immunology) Corresponding author
  63. Penzo M., Carnicelli D., Montanaro L. & Brigotti M. (2016) “A reconstituted cell-free assay for the evaluation of the intrinsic activity of purified human ribosomes” Nature Protoc. 11, 1309-1325 (I.F. 13.491, Q1 Biochemical Research Methods) Co-corresponding author
  64. Carnicelli D., Arfilli V., Onofrillo C., Alfieri R.R., Petronini P.G., Montanaro L. & Brigotti M. (2017) “Cap-independent protein synthesis is enhanced by betaine under hypertonic conditions” Biochem. Biophys. Res. Commun. 483, 936-940 (I.F. 3.575, Q2 Biophysics) Corresponding author
  65. Brighenti E., Carnicelli D., Brigotti M. & Fiume L.. (2017) “The inhibition of lactate dehydrogenase A hinders the transcription of histone 2B gene independently from the block of aerobic glycolysis” Biochem. Biophys. Res. Commun. 485, 742-745 (I.F. 3.575, Q2 Biophysics) Corresponding author
  66. He X., Ardissino G., Patfield S., Cheng L., Silva C.J. & Brigotti M. (2018) “An improved method for the sensitive detection of Shiga toxin 2 in human serum” Toxins 10, E59 (I.F. 4.546, Q1 Toxicology) Co-corresponding author
  67. Brigotti M., Carnicelli D., Arfilli V., Porcellini E., Galassi E., Valerii M.C. & Spisni E. (2018) “Human monocytes stimulated by Shiga toxin 1a via globotriaosylceramide release proinflammatory molecules associated with hemolytic uremic syndrome” International Journal of Medical Microbiology 308, 940-946 (I.F. 3.473, Q3 Microbiology) Corresponding author
  68. Brigotti M., Arfilli V., Carnicelli D., Ricci F., Tazzari P.L., Ardissino G., Scavia G., Morabito S. & He, X. (2018) “Soluble Toll-like receptor 4 impairs the interaction of Shiga toxin 2a with human serum amyloid P component” Toxins 10, E379 (I.F. 4.546, Q1 Toxicology) Co-corresponding author
  69. Brigotti M., Orth-Höller D., Carnicelli D., Porcellini E., Galassi E., Tazzari P. L., Ricci F., Manoli F., Manet I., Talasz H., Lindner H. H., Speth C., Erbeznik T., Fuchs S., Posch W., Chatterjee S. & Würzner R. (2019) “The structure of the Shiga toxin 2a A-subunit dictates the interactions of the toxin with blood components” Cellular Microbiology, 21:e13000 (I.F. 3.715, Q2 Microbiology) Co-corresponding author
  70. Turrini E., Catanzaro E., Ferruzzi L., Guerrini A., Tacchini M., Sacchetti G., Paganetto G., Maffei F., Pellicioni V., Poli F., Hrelia P., Mandrone M., Sestili P., Brigotti M. & Fimognari C. (2019) “Hemidesmus indicus induces apoptosis via proteasome inhibition and generation of reactive oxygen species" Sci. Rep. 9, 7199 (I.F. 4.379, Q1 Multidisciplinary Sciences)
  71. Sestili P., Brigotti M., Calcabrini C., Turrini E., Arfilli V., Carnicelli D., Lucarini M., Mazzanti A., Milelli A., Righi V. & Fimognari C. (2019) “Deuterium incorporation protects cells from oxidative damage” Oxidative Medicine and Cellular Longevity (I.F. 6.543, Q2 Cell Biology) Co-first author
  72. Brigotti M., He X., Carnicelli D., Arfilli V., Porcellini E., Galassi E., Tazzari P.L., Ricci F., Patfield S.A., Testa S., Paglialonga F., Picicco D., Caprioli A., Scavia G., Morabito S. & Ardissino G. (2020) “Particulate Shiga toxin 2 in blood is associated to the development of hemolytic uremic syndrome in children” Thromb. Haemost. 120, 107-120 (I.F. 5.249, Q1 Peripheral Vascular Disease) Corresponding author
  73. Ardissino G., Possenti I., Vignati C., Daprai L., Capone V., Brigotti M., Luini M.V., Consonni D. &, Montini G. (2020) “Is Shigatoxin 1 protective for the development of Shigatoxin 2-related hemolytic uremic syndrome in children? Data from the ItalKid-HUS Network” Pediatr. Nephrol. 35, 1997-2001 (I.F. 3.714, Q1 Pediatrics)
  74. Rocchetti L., Munari B., Varrone E., Porcellini E., Orth-Höller D., Würzner R., Carnicelli D. & Brigotti M. (2021) “Method for the detection of the cleaved form of Shiga toxin 2a added to normal human serum” Toxins 13, 94 (I.F. 4.546, Q1 Toxicology) Corresponding author
  75. Varrone E., Carnicelli D. & Brigotti M. (2021) “Extracellular vesicles and renal endothelial cells: a fatal attraction in hemolytic uremic syndrome” Am. J. Pathol. 191:795-804 (I.F. 4.307, Q2 Pathology) Corresponding author
  76. Ardissino G., Vignati C., Masia C., Capone V., Colombo R., Tel F., Daprai L., Testa S., Dodaro A., Paglialonga F., Luini M., Brigotti M., Picicco D., Baldioli C., Pagani F., Ceruti R., Tommasi P., Possenti I., Cresseri D., Consonni D., Montini G., Arghittu M. & ItalKid-HUS Network. (2021) “Bloody Diarrhea and STEC-HUS in Children: Data from the ItalKid-HUS Network” Journal of Pediatrics (I.F. 4.406, Q1 Pediatrics)

 

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