1975 – Born in Bologna, Italy
2002 – Master degree in Chemistry and Pharmaceutical Technologies at the Alma Mater Studiorum – Università di Bologna. Mark: 110/110 cum laude.
2007 – Ph. D. degree in Medicinal Chemistry at the Alma Mater Studiorum – Università di Bologna.
2007–2008 – Post-Doctoral research fellow at the Swiss Federal Institute of Technology: Computational Sciences – Research Group Parrinello (Lugano, Switzerland).
2008–2010 – Post-Doctoral research fellow at the Istituto Italiano di Tecnologia (IIT): Department of Drug Discovery and Development (D3, Genova, Italy).
2010–2016 – Post-Doctoral research fellow at the Alma Mater Studiorum – Università di Bologna: Department of Pharmacy and Biotechnology (Bologna, Italy).
Since October 2016, he is Fixed-term Senior Assistant Professor at the University of Bologna.
Doctor Masetti is specialized in the development of QSAR models and molecular docking protocols aimed to predict cardiac toxicity mediated by the hERG channel blockade. He is an expert of molecular dynamics simulations, which he applied to a number of pharmaceutical relevant targets and in particular to membrane proteins (potassium channels, transporters, etc.). He is been also involved in the rationalization of the functionality of proteins belonging to the endocannabinoid system, transcription factors, and several targets involved with cancer. His main scientific interest is to develop and apply innovative strategies to compute the protein-ligand binding free energy.
