Evangelista, Dominga; Nelson, Elliot; Skyner, Rachael; Tehan, Ben; Bernetti, Mattia; Roberti, Marinella; Bolognesi, Maria Laura; Bottegoni, Giovanni, Application of Deep Learning to Predict the Persistence, Bioaccumulation, and Toxicity of Pharmaceuticals, «JOURNAL OF CHEMICAL INFORMATION AND MODELING», 2025, 65, pp. 3248 - 3261 [Scientific article]
Masi, Mirco; Poppi, Laura; Previtali, Viola; Nelson, Shannon R; Wynne, Kieran; Varignani, Giulia; Falchi, Federico; Veronesi, Marina; Albanesi, Ennio; Tedesco, Daniele; De Franco, Francesca; Ciamarone, Andrea; Myers, Samuel H; Ortega, Jose Antonio; Bagnolini, Greta; Ferrandi, Giovanni; Farabegoli, Fulvia; Tirelli, Nicola; Di Stefano, Giuseppina; Oliviero, Giorgio; Walsh, Naomi; Roberti, Marinella; Girotto, Stefania; Cavalli, Andrea, Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity, «CELL DEATH DISCOVERY», 2025, 11, Article number: 106 , pp. 1 - 23 [Scientific article]Open Access
Ferrandi, Giovanni; Poppi, Laura; Bagnolini, Greta; Previtali, Viola; Roberti, Marinella; Cavalli, Andrea, Design and synthesis of RAD51-BRCA2 disruptors to inhibit homologous recombination and achieve synthetic lethality in pancreatic cancer cells, in: XXVIII EFMC International Symposium on Medicinal Chemistry, 2024(atti di: XXVIII EFMC International Symposium on Medicinal Chemistry, Roma, 1st September 2024) [Poster]
Ferrandi, Giovanni; Poppi, Laura; Bagnolini, Greta; Falchi, Federico; Previtali, Viola; Girotto, Stefania; Roberti, Marinella; Cavalli, Andrea, Design and synthesis of RAD51-BRCA2 protein-protein interaction disruptors
to trigger synthetic lethality with Olaparib in pancreatic cancer cells, in: National Congress of the Italian Chemistry Society 2024, 2024(atti di: SCI 2024 Chemistry ELEMENTS OF FUTURE, Milano, 26th August 2024) [Poster]
Previtali, Viola; Masi, Mirco; Poppi, Laura; Varignani, Giulia; Falchi, Federico; Tedesco, Daniele; Wynne, Kieran; Oliviero, Giorgio; Bagnolini, Greta; Farabegoli, Fulvia; DI STEFANO, Giuseppina; Girotto, Stefania; Roberti, Marinella; Cavalli, Andrea, Differential enantiomers activity of ARN24089 to achieve synthetic lethality in pancreatic cancer, in: 1, 2024(atti di: EFMC ISMC XXVIII EFMC International Symposium on Medicinal Chemistry, Rome, 1-5 September 2024) [Poster]
Previtali, Viola; Bagnolini, Greta; Ciamarone, Andrea; Ferrandi, Giovanni; Rinaldi, Francesco; Myers, Samuel Harry; Roberti, Marinella; Cavalli, Andrea, New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives, «JOURNAL OF MEDICINAL CHEMISTRY», 2024, 1, pp. 11488 - 11521 [Scientific article]Open Access
Sdei, Federico; Bagnolini, Greta; Falchi, Federico; Ghezzo, M.; Sosic, Alice; Sissi, Claudia; Roberti, Marinella; Bolognesi, MARIA LAURA, Targeting RNA degradation with small molecules: design and synthesis of selective RNA binders and development of ribonuclease targeting chimeras (RIBOTACs), in: 1, 2024(atti di: XXVIII Congresso Nazionale della Società Chimica Italiana - Elementi di Futuro, Milan, 26-30 August 2024) [Poster]
Myers, S. H.; Poppi, L.; Rinaldi, F.; Veronesi, M.; Ciamarone, A.; Previtali, V.; Bagnolini, G.; Schipani, F.; Ortega Martínez, J. A.; Girotto, S.; Di Stefano, G.; Farabegoli, F.; Walsh, N.; De Franco, F.; Roberti, M.; Cavalli, A., An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 265, Article number: 116114 , pp. 1 - 20 [Scientific article]Open Access
Mazzucato, R.; Roberti, M.; Capelli, A. M.; Rancati, F.; Biagetti, M.; Fiorelli, C.; Bruno, P.; Ronchi, P.; Bertolini, S.; Corsi, M.; Pala, D., Application of an “inhalation by design” approach to the identification and in-vitro evaluation of novel purine based PI3Kδ inhibitors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 254, Article number: 115331 , pp. 1 - 15 [Scientific article]Open Access
Ferrandi, Giovanni; Bagnolini, Greta; Roberti, Marinella; Cavalli, Andrea, Design and synthesis of RAD51-BRCA disruptors to inhibit homologous recombination and achieve synthetic lethality in cancer cells, in: 42nd edition of European School of Medicinal Chemistry, ESMEC, 2023(atti di: European School of Medicinal Chemistry, ESMEC, Urbino, 2nd July 2023) [Poster]
Brusa, Irene; Sondo, Elvira; Pesce, Emanuela; Tomati, Valeria; Gioia, Dario; Falchi, Federico; Balboni, Beatrice; Ortega Martínez, Jose Antonio; Veronesi, Marina; Romeo, Elisa; Margaroli, Natasha; Recanatini, Maurizio; Girotto, Stefania; Pedemonte, Nicoletta; Roberti, Marinella; Cavalli, Andrea, Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5, «JOURNAL OF MEDICINAL CHEMISTRY», 2023, 66, pp. 9797 - 9822 [Scientific article]Open Access
Previtali V.; Myers S.H.; Poppi L.; Wynne K.; Casamassima I.; Girotto S.; Di Stefano G.; Farabegoli F.; Roberti M.; Oliviero G.; Cavalli A., Preomic profile of BxPC-3 cells after treatment with BRC4, «JOURNAL OF PROTEOMICS», 2023, 288, Article number: 104983 , pp. 1 - 11 [Scientific article]Open Access
Viola Previtali, Samuel H. Myers, Laura Poppi, Kieran Wynne, Irene Casamassima Stefania Girotto, Giuseppina Di Stefano, Fulvia Farabegoli, Marinella Roberti, Giorgio Oliviero, Andrea Cavalli, Proteomic profile of BxPC-3 cells after treatment with BRC4, «JOURNAL OF PROTEOMICS», 2023, 288, pp. 1 - 11 [Scientific article]
Bagnolini, G.; Falchi, F.; Sdei, F.; Roberti, M.; Sosic, A.; Sissi, C.; Bolognesi, M. L., Triggering RNA degradation with small molecules: development of RIBOnuclease TArgeting Chimeras (RIBOTACs), in: Book of abstract, 2023(atti di: XXVIII National Meeting on Medicinal Chemistry (NMMC28), Chieti, 17-20 September 2023) [Poster]
Salerno, Alessandra; Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Testi, Eleonora; Guardigni, Melissa; Roberti, Marinella; Milelli, Andrea; Bolognesi, Maria Laura, Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 9507 - 9530 [Scientific article]Open Access
