Ferrandi, Giovanni; Poppi, Laura; Bagnolini, Greta; Previtali, Viola; Roberti, Marinella; Cavalli, Andrea, Design and synthesis of RAD51-BRCA2 disruptors to inhibit homologous recombination and achieve synthetic lethality in pancreatic cancer cells, in: XXVIII EFMC International Symposium on Medicinal Chemistry, 2024(atti di: XXVIII EFMC International Symposium on Medicinal Chemistry, Roma, 1st September 2024) [Poster]
Ferrandi, Giovanni; Poppi, Laura; Bagnolini, Greta; Falchi, Federico; Previtali, Viola; Girotto, Stefania; Roberti, Marinella; Cavalli, Andrea, Design and synthesis of RAD51-BRCA2 protein-protein interaction disruptors
to trigger synthetic lethality with Olaparib in pancreatic cancer cells, in: National Congress of the Italian Chemistry Society 2024, 2024(atti di: SCI 2024 Chemistry ELEMENTS OF FUTURE, Milano, 26th August 2024) [Poster]
Previtali, Viola; Bagnolini, Greta; Ciamarone, Andrea; Ferrandi, Giovanni; Rinaldi, Francesco; Myers, Samuel Harry; Roberti, Marinella; Cavalli, Andrea, New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives, «JOURNAL OF MEDICINAL CHEMISTRY», 2024, 1, pp. 1 - 34 [Scientific article]
Myers, S. H.; Poppi, L.; Rinaldi, F.; Veronesi, M.; Ciamarone, A.; Previtali, V.; Bagnolini, G.; Schipani, F.; Ortega Martínez, J. A.; Girotto, S.; Di Stefano, G.; Farabegoli, F.; Walsh, N.; De Franco, F.; Roberti, M.; Cavalli, A., An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 265, Article number: 116114 , pp. 1 - 20 [Scientific article]Open Access
Mazzucato, R.; Roberti, M.; Capelli, A. M.; Rancati, F.; Biagetti, M.; Fiorelli, C.; Bruno, P.; Ronchi, P.; Bertolini, S.; Corsi, M.; Pala, D., Application of an “inhalation by design” approach to the identification and in-vitro evaluation of novel purine based PI3Kδ inhibitors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 254, Article number: 115331 , pp. 1 - 15 [Scientific article]
Ferrandi, Giovanni; Bagnolini, Greta; Roberti, Marinella; Cavalli, Andrea, Design and synthesis of RAD51-BRCA disruptors to inhibit homologous recombination and achieve synthetic lethality in cancer cells, in: 42nd edition of European School of Medicinal Chemistry, ESMEC, 2023(atti di: European School of Medicinal Chemistry, ESMEC, Urbino, 2nd July 2023) [Poster]
Brusa, Irene; Sondo, Elvira; Pesce, Emanuela; Tomati, Valeria; Gioia, Dario; Falchi, Federico; Balboni, Beatrice; Ortega Martínez, Jose Antonio; Veronesi, Marina; Romeo, Elisa; Margaroli, Natasha; Recanatini, Maurizio; Girotto, Stefania; Pedemonte, Nicoletta; Roberti, Marinella; Cavalli, Andrea, Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5, «JOURNAL OF MEDICINAL CHEMISTRY», 2023, 66, pp. 9797 - 9822 [Scientific article]Open Access
Previtali V.; Myers S.H.; Poppi L.; Wynne K.; Casamassima I.; Girotto S.; Di Stefano G.; Farabegoli F.; Roberti M.; Oliviero G.; Cavalli A., Preomic profile of BxPC-3 cells after treatment with BRC4, «JOURNAL OF PROTEOMICS», 2023, 288, Article number: 104983 , pp. 1 - 11 [Scientific article]Open Access
Viola Previtali, Samuel H. Myers, Laura Poppi, Kieran Wynne, Irene Casamassima Stefania Girotto, Giuseppina Di Stefano, Fulvia Farabegoli, Marinella Roberti, Giorgio Oliviero, Andrea Cavalli, Proteomic profile of BxPC-3 cells after treatment with BRC4, «JOURNAL OF PROTEOMICS», 2023, 288, pp. 1 - 11 [Scientific article]
Salerno, Alessandra; Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Testi, Eleonora; Guardigni, Melissa; Roberti, Marinella; Milelli, Andrea; Bolognesi, Maria Laura, Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 9507 - 9530 [Scientific article]Open Access
Samuel Harry Myers , Viola Previtali, Laura Poppi, Francesco Rinaldi, Fabrizio Schipani, Jose Antonio Ortega, Francesca De Franco, Marina Veronesi, Roberto Pellicciari, Marinella Roberti, Stefania Girotto, Giuseppina Di Stefano, Andrea Cavalli, Identification and subsequent development of RAD51-BRCA2 disruptors through a fragment-based approach, in: ACS Spring 2022, 2022, pp. 1 - 1 (atti di: ACS Spring 2022, San Diego Convention Center, Room 16A, 20/03/2022) [Abstract]
Bagnolini, G.; Balboni, B.; Schipani, F.; Gioia, D.; Veronesi, M.; De Franco, F.; Kaya, C.; Jumde, R. P.; Ortega, J. A.; Girotto, S.; Hirsch, A. K. H.; Roberti, M.; Cavalli, A., Identification of RAD51-BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry, «ACS MEDICINAL CHEMISTRY LETTERS», 2022, 13, pp. 1262 - 1269 [Scientific article]Open Access
Previtali V., Myers S. H., Bagnolini G., Poppi L., Rinaldi F., Schipani F., Ortega J. A., De Franco F., Pellicciari R., Girotto S., Oliviero G., Walsh N., Valenti G., Tirelli N., Di Stefano G., Roberti M., Cavalli A., Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer, in: ACS Spring 2022, 2022, pp. 1 - 1 (atti di: ACS Spring 2022, San Diego Convention Center, Room 16A, 20/03/2023) [Abstract]
Brusa I.; Sondo E.; Falchi F.; Pedemonte N.; Roberti M.; Cavalli A., Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 5212 - 5243 [Scientific article]Open Access
Schipani, Fabrizio; Manerba, Marcella; Marotta, Roberto; Poppi, Laura; Gennari, Arianna; Rinaldi, Francesco; Armirotti, Andrea; Farabegoli, Fulvia; Roberti, Marinella; Di Stefano, Giuseppina; Rocchia, Walter; Girotto, Stefania; Tirelli, Nicola; Cavalli, Andrea, The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2022, 23, Article number: 8338 , pp. 1 - 14 [Scientific article]Open Access
