Laura Poppi, Samuel H Myers, Viola Previtali, Francesco Rinaldi, Fulvia Farabegoli, Giuseppina Di Stefano, Naomi Walsh, Marinella Roberti, Andrea Cavalli, A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer, in: EACR 2023: Innovative Cancer Science, 12-15 June 2023, Torino, Italy, FEBS PRESS, 2023, pp. 1 - 597 (atti di: EACR 2023: Innovative Cancer Science, Torino, Italy, 12-15 June 2023) [atti di convegno-poster]
Myers S. H., Poppi L., Rinaldi F., Veronesi M., Ciamarone A., Previtali V., Bagnolini G., Schipani F., Ortega Martínez J. A., Girotto S., Di Stefano G., Farabegoli F., Walsh N., De Franco F., Roberti M., Cavalli A., An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 265, pp. 1 - 20 [articolo]
Mazzucato R.; Roberti M.; Capelli A.M.; Rancati F.; Biagetti M.; Fiorelli C.; Bruno P.; Ronchi P.; Bertolini S.; Corsi M.; Pala D., Application of an “inhalation by design” approach to the identification and in-vitro evaluation of novel purine based PI3Kδ inhibitors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 254, Article number: 115331, pp. 1 - 15 [articolo]
Brusa, Irene; Sondo, Elvira; Pesce, Emanuela; Tomati, Valeria; Gioia, Dario; Falchi, Federico; Balboni, Beatrice; Ortega Martínez, Jose Antonio; Veronesi, Marina; Romeo, Elisa; Margaroli, Natasha; Recanatini, Maurizio; Girotto, Stefania; Pedemonte, Nicoletta; Roberti, Marinella; Cavalli, Andrea, Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5, «JOURNAL OF MEDICINAL CHEMISTRY», 2023, 66, pp. 9797 - 9822 [articolo]Open Access
Previtali V.; Myers S.H.; Poppi L.; Wynne K.; Casamassima I.; Girotto S.; Di Stefano G.; Farabegoli F.; Roberti M.; Oliviero G.; Cavalli A., Preomic profile of BxPC-3 cells after treatment with BRC4, «JOURNAL OF PROTEOMICS», 2023, 288, Article number: 104983, pp. 1 - 11 [articolo]
Salerno, Alessandra; Seghetti, Francesca; Caciolla, Jessica; Uliassi, Elisa; Testi, Eleonora; Guardigni, Melissa; Roberti, Marinella; Milelli, Andrea; Bolognesi, Maria Laura, Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 9507 - 9530 [articolo]Open Access
Samuel Harry Myers , Viola Previtali, Laura Poppi, Francesco Rinaldi, Fabrizio Schipani, Jose Antonio Ortega, Francesca De Franco, Marina Veronesi, Roberto Pellicciari, Marinella Roberti, Stefania Girotto, Giuseppina Di Stefano, Andrea Cavalli, Identification and subsequent development of RAD51-BRCA2 disruptors through a fragment-based approach, in: ACS Spring 2022, 2022, pp. 1 - 1 (atti di: ACS Spring 2022, San Diego Convention Center, Room 16A, 20/03/2022) [atti di convegno-abstract]
Bagnolini, G.; Balboni, B.; Schipani, F.; Gioia, D.; Veronesi, M.; De Franco, F.; Kaya, C.; Jumde, R. P.; Ortega, J. A.; Girotto, S.; Hirsch, A. K. H.; Roberti, M.; Cavalli, A., Identification of RAD51-BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry, «ACS MEDICINAL CHEMISTRY LETTERS», 2022, 13, pp. 1262 - 1269 [articolo]Open Access
Previtali V., Myers S. H., Bagnolini G., Poppi L., Rinaldi F., Schipani F., Ortega J. A., De Franco F., Pellicciari R., Girotto S., Oliviero G., Walsh N., Valenti G., Tirelli N., Di Stefano G., Roberti M., Cavalli A., Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer, in: ACS Spring 2022, 2022, pp. 1 - 1 (atti di: ACS Spring 2022, San Diego Convention Center, Room 16A, 20/03/2023) [atti di convegno-abstract]
Brusa I.; Sondo E.; Falchi F.; Pedemonte N.; Roberti M.; Cavalli A., Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 5212 - 5243 [articolo]Open Access
Schipani, Fabrizio; Manerba, Marcella; Marotta, Roberto; Poppi, Laura; Gennari, Arianna; Rinaldi, Francesco; Armirotti, Andrea; Farabegoli, Fulvia; Roberti, Marinella; Di Stefano, Giuseppina; Rocchia, Walter; Girotto, Stefania; Tirelli, Nicola; Cavalli, Andrea, The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2022, 23, Article number: 8338, pp. 1 - 14 [articolo]Open Access
Bruno F.; Castelli G.; Vitale F.; Catanzaro S.; Badaco V.V.; Roberti M.; Colomba C.; Cascio A.; Tolomeo M., Antiparasitic effect of stilbene and terphenyl compounds against trypanosoma cruzi parasites, «PHARMACEUTICALS», 2021, 14, Article number: 1199, pp. 1 - 16 [articolo]Open Access
Mazzei L.; Contaldo U.; Musiani F.; Cianci M.; Bagnolini G.; Roberti M.; Ciurli S., Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies, «ANGEWANDTE CHEMIE. INTERNATIONAL EDITION», 2021, 60, pp. 6029 - 6035 [articolo]
Balboni A.; Govoni M.; Rossi V.; Roberti M.; Cavalli A.; Di Stefano G.; Manerba M., Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment, «BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS», 2021, 1865, Article number: 129760, pp. 1 - 10 [articolo]
Vetica F.; Sansone A.; Meliota C.; Batani G.; Roberti M.; Chatgilialoglu C.; Ferreri C., Free-radical-mediated formation of trans-cardiolipin isomers, analytical approaches for lipidomics and consequences of the structural organization of membranes, «BIOMOLECULES», 2020, 10, Article number: 1189, pp. 1 - 18 [articolo]Open Access
