Keywords:
Human Evolutionary Genomics
Human Adaptability
Evolutionary Medicine
Human Biodiversity
Research activity is focused on the study of genomic
variability of human populations from an evolutionary perspective by means of the characterization of autosomal molecular markers through SNP arrays or massive parallel sequencing of whole genomes,
it is carried out within the framework of different research projects and with two
main goals:
- investigating the evolutionary history of genomic regions
subjected to selective pressures to shed lights on the genetic
bases of human adaptations and its crucial medical implications, in
the attempt to understand the role played by natural selection in
different socio-cultural contexts and its impact on the susceptibility of modern
populations to complex diseases (related projects:
CROSSING THE SEA, SHERPA, fineMEX, MEX, PH-NGS, EPIC, NGS-PTL, PsA GWAS, TASTE GENETIC GEOGRAPHY);
- depicting the genetic structure and history of human
populations to dissect biological, demographic and cultural
factors that have mainly shaped the evolution of the genome of
their individuals (related projects: CROSSING THE SEA, LANGELIN, GENOGRAPHIC Italia, ISOLATING THE ISOLATES)
