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Marco Candela

Professore ordinario

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHIM/11 CHIMICA E BIOTECNOLOGIA DELLE FERMENTAZIONI

Pubblicazioni

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Pubblicazioni antecedenti il 2004

Publications

1.     Rampelli S, Schnorr SL, Consolandi C, Turroni S, Severgnini M, Peano C, Brigidi P, Crittenden AN, Henry AG and Candela M. Metagenome sequencing of the Hadza hunter-gatherer gut microbiota. Current Biology. May 2015. doi: 10.1016/j.cub.2015.04.055.

2.     Biagi E, Zama D, Nastasi C, Consolandi C, Fiori J, Rampelli S, Turroni S, Centanni M, Severgnini M, Peano C, de Bellis G, Basaglia G, Gotti R, Masetti R, Pession A, Brigidi P and Candela M. Gut microbiota trajectory in pediatric patients undergoing hematopoietic stem cell transplantation. Bone Marrow Transplantation. 2015 Apr 20. doi: 10.1038/bmt.2015.16.

3.     Consolandi C, Turroni S, Emmi G, Severgnini M, Fiori J, Peano C, Biagi E, Grassi A, Rampelli S, Silvestri E, Centanni M, Cianchi F, Gotti R, Emmi L, Brigidi P, De Bellis G, Prisco D, Candela M & D'Elios MM. Dysbioses of the gut microbiota in patients with Behçet's syndrome. Autoimmun Rev. 2015 Apr;14(4):269-76. doi: 10.1016/j.autrev.2014.11.009.

4.     Quercia S., Candela M., Giuliani C., Turroni S., Luiselli D., Rampelli S., Brigidi P., Franceschi C., Bacalini M.G., Garagnani P. and Pirazzini C. From lifetime to evolution: timescales of human gut microbiota adaptation. Frontiers in Microbiology. 2014 Nov 4;5:587. doi: 10.3389/fmicb.2014.00587.

5.     Spisni E, Valerii MC, De Fazio L, Cavazza E, Borsetti F, Sgromo A, Candela M, Centanni M, Rizello F, Strillacci A. Cyclooxygenase-2 silencing for the treatment of colitis: a combined in vivo strategy based on RNA interference and engineered Escherichia coli. Mol Ther. 2014 Nov 13. doi: 10.1038/mt.2014.222.

6.     Biagi E, Candela M, Centanni M, Consolandi C, Rampelli S, Turroni S, Severgnini M, Peano C, Ghezzo A, Scurti M, Salvioli S, Franceschi C, Brigidi P. Gut microbiome in down syndrome. PLoS One. 2014 Nov 11;9(11):e112023. doi: 10.1371/journal.pone.0112023. eCollection 2014

7.     Centanni M., Turroni S., Simone R., Biagi E., Quercia S., Consolandi C., Severgnini M., Brigidi P., Candela M. Bifidobacterium animalis subsp. lactis BI07 modulates the TNFα-dependent unbalances of the enterocyte associated intestinal microbiota fraction. FEMS Microbiol Lett. 2014 Jun 25. doi: 10.1111/1574-6968.12515.

8.     Moco S., Candela M., Chuang E., Draper C., Cominetti O., Montoliou I., Kussmann M., Brigidi P., Gionchetti P. and Martin F.P.J. Systems biology approaches for IBD: emphasis on gut microbial metabolism. Inflammatory Bowel Diseases. May 2014. Accepted for publication in the journal.

9.     Saa D., Turroni S., Serrazanetti D., Rampelli S., Maccaferri S., Candela M., Severgnini M., Simonetti E., Brigidi P., Gianotti A. Impact of Kamut®  Khorasan on gut microbiota and metabolome in healthy volunteers. Food Research International. April 2014.

10.  Garagnani P., Pirazzini C., Giuliani C., Candela M., Brigidi P., Sevini F., Luiselli D., Bacalini M.G., Salvioli S., Capri M., Monti D., Mari D., Collino S., Delledonne M., Descombes P., Franceschi C. The three genetics (nuclear DNA, mitochondrial DNA and gut microbiome) of longevity in humans considered as metaorganisms. BioMed Research International. March 2014. Accepted for publication in the journal.

11.  Schnorr SL.†, Candela M.†, Rampelli S., Centanni M., Consolandi C., Basaglia G., Turroni S., Biagi E., Peano C., Severgnini M., Fiori J., Gotti R., De Bellis G., Luiselli D., Brigidi P., Mabulla A., Marlowe F., Crittenden A.N., Henry A.G. Gut microbiome from the Hadza hunter-gatherers. Nature Communication. 2014 Apr 15;5:3654. doi: 10.1038/ncomms4654. († These authors contributed equally to the work).

12.  Piazzi G., D'argenio G., Prossomariti A., Lembo V., Mazzone G., Candela M., Biagi E., Brigidi P., Vitaglione P., Fogliano V., D'angelo L., Fazio C., Munarini A., Belluzzi A., Ceccarelli C., Chieco P., Balbi T., Loadman P., Hull, M., Romano M., Bazzoli, F., Ricciardiello L. Eicosapentaenoic acid free fatty acid prevents and suppresses colonic neoplasia in colitis-associated colorectal cancer acting on Notch signaling and gut microbiota. International Journal of Cancer. 2014 Mar 19. doi: 10.1002/ijc.28853. [Epub ahead of print].

13.  Candela M. , Turroni S., Biagi E., Carbonero F., Rampelli S., Fiorentini C., Brigidi P. Inflammation and colorectal cancer, when microbiota-host mutualism breaks. World Journal of Gastroenterology. 2014 Jan 28;20(4):908-922.

14.  De Fazio L., Cavazza E., Spisni E., Strillacci A., Centanni M., Candela M., Praticò C., Campieri M., Ricci, Maria C., Valerii C. Longitudinal analysis of inflammation and microbiota dynamics in a model of mild chronic dextran sulphate sodium-induced colitis in mice. World Journal of Gastroenterology. World J Gastroenterol. 2014 Feb 28;20(8):2051-61. doi: 10.3748/wjg.v20.i8.2051.

15.  Candela M. , Biagi E., Brigidi P., O'Toole P.W., De Vos W.M. Maintenance of a healthy trajectory of the intestinal microbiome during aging: a dietary approach. Mechanisms of Ageing and Development. 2014. 2014 Mar-Apr;136-137:70-5. doi: 10.1016/j.mad.2013.12.004. Epub 2013 Dec 25.

16.  Rampelli S., Candela M., Turroni S., Biagi E., Collino S., Franceschi C., O'Toole P.W., Brigidi P. Functional metagenomic profiling of intestinal microbiome in extreme ageing. 2013. AGING. Vol 5 N 12

17.  Centanni M., Turroni S., Consolandi C., Rampelli S., Peano C., Severgnini M., Biagi E., Caredda G., De Bellis G., Brigidi P., Candela M. The enterocyte-associated intestinal microbiota of breast-fed infants and adults responds differently to a TNF- α -mediated pro-inflammatory stimulus. PLoS ONE. 2013 November 26, DOI: 10.1371/journal.pone.0081762.

18.  Candela M. , Biagi E., Turroni S., Maccaferri S., Figini P., Brigidi P. Dynamic efficiency of the human intestinal microbiota. Critical Reviews in Microbiology, 2013. Sept, Online published.

19.  Centanni M., Turroni S., Biagi E., Severgnini M., Consolandi C., Brigidi P., Candela M. A novel combined approach based on HTF-Microbi.Array and qPCR for a reliable characterization of the Bifidobacterium-dominated gut microbiota of breast-fed infants. FEMS Microbiol Lett. 2013 Mar 25. doi: 10.1111/1574-6968.12138. [Epub ahead of print]

20.  Rampelli S., Candela M., Severgnini M., Biagi E., Turroni S., Roselli M., Carnevali P., Donini L., Brigidi P. A probiotics-containing biscuit modulates the intestinal microbiota in the elderly. Journal of Nutrition, Health and Aging. 2013;17(2):166-72. doi: 10.1007/s12603-012-0372-x.

21.  Biagi E., Candela M., Turroni S., Garagnani P., Franceschi C., Brigidi P. Ageing and gut microbes: perspectives for health maintenance and longevity. Pharmacol Res. 2013 Mar;69(1):11-20. doi: 10.1016/j.phrs.2012.10.005.

22.  Vastano V., Capri U., Candela M., Siciliano R. A., Russo L., Renda M., Sacco M. Identification of binding sites of Lactobacillus plantarum enolase involved in the interaction with human plasminogen. Microbiological Research. 2013 Feb 22;168(2):65-72. doi: 10.1016/j.micres.2012.10.001.

23.  Vitali B., Cruciani F., Baldassarre M.E., Capursi T., Spisni E., Valerii M.C., Candela M., Turroni S. and Brigidi P. Dietary supplementation with probiotics during late pregnancy: outcome on vaginal microbiota and cytokine secretion. BMC Microbiol. 2012 Oct 18;12(1):236

24.  Maccaferri S., Candela M., Turroni S., Centanni M., Severgnini M., Consolandi C., Cavina P., Brigidi P., IBS-associated phylogenetic unbalances of the intestinal microbiota are not reverted by probiotic supplementation. GutMicrobes. 2012. Gut Microbes 3:5, 1-8.

25.  Candela M., Biagi E., Maccaferri S., Turroni S. and Brigidi P. Intestinal microbiota is a plastic factor responding to environmental changes. Trends Microbiol. 2012 Aug; 20(8): 385-91

26.  Candela M. , Rampelli S., Turroni S., Severgnini M., Consolandi C., De Bellis G., Masetti R., Ricci G., Pession A., Brigidi P. Unbalance of Intestinal Microbiota in Atopic Children . BMC Microbiol. 2012 Jun 6;12(1):95.

27.  Centanni M., Bergmann S., Turroni S., Hammerschmidt S., Chhatwal G.S., Brigidi P. and Candela M. Tumor Necrosis Factor Alpha Modulates the Dynamics of the Plasminogen-Mediated Early Interaction between Bifidobacterium animalis subsp. lactis and Human Enterocytes. Appl Environ Microbiol. 2012 April; 78(7): 2465-9.

28.  Cariani A., Piano A., Consolandi C., Severgnini M., Castiglioni B., Caredda G., Candela M., Serratore P., De Bellis G., Tinti F. Detection and Characterization of Pathogenic Vibrios in Shellfish by a Ligation Detection Reaction-Universal Array approach. Int. J. Food Microbiol. 2012. 153: 474–482.

29.  Biagi E., Candela M., Fairweather-Tait S., Franceschi C., Brigidi P. Aging of the human metaorganism: the microbial counterpart. AGE, 2012 Feb 24.

30.  Candela M. , Turroni S., Centanni M., Fiori J., Bergmann S., Hammerschmidt S. and Brigidi P. Relevance of the Bifidobacterium animalis subsp. lactis plasminogen binding activity in the human gastrointestinal microenvironment. Appl Environ Microbiol. 2011 Oct;77(19):7072-6.

31.  Ottaviani E., Ventura N., Mandrioli M., Candela M., Franchini A., Franceschi C. Gut microbiota as a candidate for lifespan extension: an ecological/evolutionary perspective targeted on living organisms as metaorganisms . Biogerontology. 2011 Aug 4.

32.  Biagi E., Candela M., Franceschi C., Brigidi P. The aging gut microbiota: new perspectives. Ageing Res Rev, 2011 Mar 23.

33.  Candela M. , Guidotti M., Fabbri A., Brigidi P., Franceschi C. and Fiorentini C. Human intestinal microbiota: cross-talk with the host and its potential role in colorectal cancer. Critical Reviews in Microbiology, 2011. 37; 1-14.

34.  Candela M ., Fiori J; Dipalo S; Brigidi P. Development of a high-performance affinity chromatography-based method to study the biological interaction between whole microorganisms and target proteins. Lett Appl Microbiol. 2010. 51; 678-82

35.  Turroni S., Bendazzoli C., Dipalo S.C., Candela M., Vitali B., Gotti R., Brigidi P. Oxalate-degrading activity in Bifidobacterium animalis subsp. lactis: impact of acidic conditions on the transcriptional levels of oxalyl-CoA decarboxylase and formyl-CoA transferase genes. Appl Environ Microbiol. 2010. 76; 5609-20.

36.  Biagi E., Nylund L., Candela M., Ostan R., Bucci L., Pini E., Nikkïla J., Monti D., Satokari R., Franceschi C., Brigidi P., and De Vos W. Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. PLoS ONE. 2010. 5; e10667

37.  Candela M. , Maccaferri S., Turroni S., Carnevali P., Brigidi P. Functional Intestinal Microbiome, New Frontiers in Prebiotic Design. Int. J. Food Microbiol. 2010. 140; 93-101.

38.  Candela M. , Consolandi C., Severgnini M., Biagi E., Castiglioni B., Vitali B., De Bellis G. and Brigidi P. High taxonomic level fingerprint of the human intestinal microbiota by Ligase Detection Reaction - Universal Array approach. BMC Microbiol. 2010. 10; 116.

39.  Candela M. , Centanni M., Fiori J., Biagi E., Turroni S., Orrico C., Bergmann S., Hammerschmidt S., Brigidi P. DnaK from Bifidobacterium animalis subsp. lactis is a surface-exposed human plasminogen receptor upregulated in response to bile salts. Microbiology. 2010. 156; 1609-18.

40.  Vitali B., Ndagijimana M., Cruciani F., Carnevali P., Candela M., Guerzoni M.E. and Brigidi P. Impact of a synbiotic food on the gut microbial ecology and metabolic profiles. BMC Microbiol. 2010. 10; 4.

41.  Turroni S., Vitali B., Candela M., Gionchetti P., Rizzello F., Campieri M., Brigidi P. Antibiotics and probiotics in chronic pouchitis: a comparative proteomic approach. World J. Gastroenterol. 2010. 16; 30-41.

42.  Candela M. , Biagi E., Centanni M., Turroni S., Vici M., Musiani F., Vitali B., Bergmann S., Hammerschmidt S., Brigidi P. Bifidobacterial enolase, a cell surface receptor for human plasminogen involved in the interaction with the host. Microbiology. 2009. 155; 3294-303.

43.  Castaldo C., Vastano V., Siciliano R. A., Candela M., Vici M., Muscariello L., Marasco R., Sacco M.. Surface displaced alfa-enolase of Lactobacillus plantarum is a fibronectin binding protein. Microb. Cell. Fact. 2009. 16; 8-14

44.  Candela M. , Biagi E., Turroni S., Vitali B. and Brigidi P. Mechanisms involved in the intestinal interaction between host and bifidobacteria. Microbial Ecology in Health and Disease. 2008. 1-4.

45.  Biagi E., Vitali B., Pugliese C., Candela M., Donders G. G., Brigidi P.. Quantitative variations in vaginal bacterial population associated with asymptomatic infections: a real time PCR study. Eur. J. Clin. Microbiol. Infect. Dis. 2008. Sep 2.

46.  Candela M. , Miccoli G., Bergmann S., Turroni S., Vitali B., Hammerschmidt S., Brigidi P. Plasminogen-dependent proteolytic activity in Bifidobacterium lactis. Microbiology. 2008. 154: 2457-2462.

47.  Candela M. , Perna F., Carnevali P., Vitali B., Ciati R., Gionchetti P., Rizzello F., Campieri M., Brigidi P. Interaction of probiotic Lactobacillus and Bifidobacterium strains with human intestinal epithelial cells: adhesion properties, competition against enteropathogens and modulation of IL-8 production. Int. J. Food Microbiol. 2008. 125: 286-292.

48.  Candela M. , Fiori J., Dipalo S., Naldi M., Gotti R., Brigidi P. Rapid MALDI-TOF-MS analysis in the study of interaction between whole bacterial cells and human target molecules: binding of Bifidobacterium to human plasminogen. J. Microbiol. Methods. 2008. 73: 276-278.

49.  Vitali B., Turroni S., Serina S., Sosio M., Vannini L., Candela M., Guerzoni M. E., Brigidi P. Molecular and phenotypic traits of in vitro-selected mutants of Bifidobacterium resistant to rifaximin. Int. J. Antimicrob. Agents. 2008. 31: 555-560.

50.  Vitali B., Pugliese C., Biagi E., Candela M., Turroni S., Bellen G., Donders G. G., Brigidi P. Dynamics of vaginal bacterial communities in women developing bacterial vaginosis, candidiasis or no infection analysed by PCR-denaturing gradient gel electrophoresis and real time PCR. Appl. Environ. Microbiol. 2007. 73: 5731-5741.

51.  Candela M. , Bergmann S., Vici M., Vitali B., Turroni S., Eikmanns B. J., Hammerschmidt S., Brigidi P. Binding of human plasminogen to Bifidobacterium. J. Bacteriol. 2007. 189: 5929-5936.

52.  Turroni S., Vitali B., Bendazzoli C., Candela M., Gotti R., Federici F., Pirovano F., Brigidi P. Oxalate consumption by lactobacilli: evaluation of oxalyl-CoA decarboxylase and formyl-CoA transferase activity in Lactobacillus acidophilus. J. Appl. Microbiol. 2007. 103: 1600-1609.

53.  Vitali B., Turroni S., Dal Piaz F., Candela M., Wasinger V., Brigidi P. Genetic and proteomic characterization of rifaximin resistance in Bifidobacterium infantis BI07. Res. Microbiol. 2007. 158: 355-362.

54.  Candela M. , Seibold G., Vitali B., Lachenmaier S., Eikmanns B. J., Brigidi P. Real-time PCR quantification of bacterial adhesion to Caco-2 cells: competition between bifidobacteria and enteropathogens. Res. Microbiol. 2005. 156: 887-895.

55.  Candela M. , Vitali B., Matteuzzi D., Brigidi P. Evaluation of the rrn operon copy number in Bifidobacterium using real-time PCR. Lett. Appl. Microbiol. 2004. 38: 229-232.

56.  Vitali B., Candela M., Matteuzzi D., Brigidi P. Quantitative detection of probiotic Bifidobacterium strains in bacterial mixtures by using real-time PCR. Syst. Appl. Microbiol. 2003. 26: 269-276.

57.  Candela M. , Zaccherini E., Zannoni D. Respiratory electron transport and light-induced energy transduction in membranes from the aerobic photosynthetic bacterium Roseobacter denitrificans. Arch. Microbiol. 2001. 175: 168-177.

Oral comunications

1.     he is invited speaker at HUMAN GUT MICROBIOME AND DISEASES, 25-26 June 2015, Milan. Title of the talk “Trajectory of the gut microbiome during aging”

2.     he is invited speaker at International Conference FROM SEED TO PASTA & BEYOND (Bologna, 31 May - 2 June and Milan 3 June 2015). Title of the talk What kind of pasta for a healthy gut microbiome?

3.     he toke a lecture at master in alimentation and education to health, June 2015, Fondazione Alma Mater (FAM), University of Bologna, Bologna, Italy

4.     he is invited speaker at TOP TEN IN GASTROENTEROLOGIA – ISEO (BS) 13-14 Marzo 2015. Title of the talk “Microbiota intestinale: un decennio di conquiste”.

5.     he is invited speaker at 59°CONGRESSO NAZIONALE SIGG. Bologna, 26-29 Novembre 2014. Title of the talk: “Gut microbiome and longevity”. 

6.     he is invited speaker at “Nutrients Beyond Nutrition 3”, Energy: a critical issue in critical illness. International Meeting on Energy Substrates in Clinical Nutrition. Bari, Italy. 10-11 October 2014. Title of the talk: “Regulation of energy homeostasis by gut microbiota”. 

7.     he is invited speaker at “Microbiota come genotipo esteso”,'Associazione Genetica Italiana, Cortona il 23-24 Giugno 2014. Title of the talk: “Microbiota dei centenari”.

8.     he toke a lecture at master in alimentation and education to health, June 2014, Fondazione Alma Mater (FAM), University of Bologna, Bologna, Italy

9.     he is invited speaker at WORKSHOP on 454 technology and microbial biodiversity, Roche. November the 21th 2013, Milan, Italy. Title of the talk: Human Microbiome by NGS. 

10.  he is invited speaker at ISS-ARTOI 6-7 November 2013, Roma, Italy. Title of the talk: DIET INFLAMMATION AND COLORECTAL CANCER, WHEN MUTUALISM BREAKS. (M Candela, E. Biagi, S. Turroni, S. Rampelli, F. Carbonero, C. Fiorentini, P. Brigidi)

11.  he is invited speaker at EAGEN Postgraduate Course 'Gut Microbiome, Nutrition and Health' Rome 10-11 July 2013. Title of the talk: molecular assesement and role of enterotypes.

12.  he is invited speaker at  “I seminari del Mercoledi”, S. Orsola polyclinic, University of Bologna, 19 June 2013, Bologna. Title of the talk: Inflammation and colorectal cancer, when microbiota-host mutualism broke.

13.  he toke a lecture at Master "Alimentazione ed Educazione alla Salute", Fondazione Alma Mater (FAM), University of Bologna, 15 June 2013, Bologna. Title of the talk: human intestinal microbiota, structure and role in host physiology.

14.  he is invited speaker at Share Data Meeting on MARS500. Viterbo - February 6-8, 2013. Title of the talk: Impact of a controlled and confined environment on the intestinal microbiota.

15.  he is invited speaker at the conference and workshop on Bacterial toxins in inflammation and cancer. Institute of International Health, Immunology and Microbiology, University of Copenhagen, 20-22 October 2012, Copenhagen (DK). Title of the talk: bacterial driver-passenger model in colorectal cancer

16.  he toke a lecture at master in alimentation and education to health, 29th-September 2012, Fondazione Alma Mater (FAM), University of Bologna, Bologna, Italy. 

17.  he is invited speaker at SANA, 8th-11 September 2012, Bologna, Italy. The role of mediterranean diet and its nutriaceutics in modern prevention and treatment strategies. Title of the talk: Intestinal microbiome. 

18.  he is invited speaker at NutriMi, VI international forum of practical nutrition, 14th-15 March 2012, Milano, Italy. Title of the talk: Intestinal microbiome, an epigenetic factor conferring adaptation to environmental changes.

19.  he is invited speaker at the SysBioHealth, 2nd Workshop on SYSTEMS MEDICINE,14th-15th December 2011, Bologna, Italy. Title of the talk: Intestinal microbiome, an epigenetic factor conferring adaptation to environmental changes.

20.  he is invited speaker at the European Science Foundation Exploratory Workshop on Bacterial Infection as a Cause of Cancer, 2-4 October 2011, King's College, London  (UK). Title of the talk: Diet, intestinal microbiome and colorectal cancer onset.

21.  he toke a plenary lecture entitled “Intestinal microbiota, from nutrition to homeostasis of the human metaorganismpresso” at Second Edition Summer School “Nutrition between Nature and Nurture”, University of Bologna, Rimini Campus Branch, Italy June 28th – July 9th, 2010.

22.  Candela M. , Biagi E., Dipalo S., Severgnini M., Consolandi C., Castiglioni B., Turroni S., Vitali B., De Bellis G.. Development of a LDR-Universal array platform for the phylogenetic fingerprint of the Human Intestinal Microbiota. Selected for oral communication . 26° Convegno SIMGBM, 10-12 Giugno 2009, Spoleto, Italy

23.  Cariani A., Piano A., Zanaroli G., Biagi E., Severgnini M., Consolandi C., Castiglioni B., Candela M.. Sviluppo di DNA microarray per la caratterizzazione di ecosistemi microbici complessi. Selected for oral communication. Convegno BMMA 2008. Maggio 23-24, Bertinoro, Forli, Italy.

24.  he is invited speaker at the Department of Histology, Microbiology and Medical Biotechnologies, University of Padova. 18 December 2007, Padova, Italy. Title of the talk: Bifidobacterium human plasminogen interaction, molecular mechanisms and physiological role.

25.  Candela M. , Pugliese C., Turroni S., Vici M., Vitali B. and Brigidi P.. Exploitation of plasminogen-plasmin system in Bifidobacterium for the human host colonization, a common strategy between symbionts and pathogens. Selected for oral communication. 25° Convegno SIMGBM, 8-10 Giugno 2006, Orvieto, Italy.

26.  Candela M. , Vici M., Dal Piaz F., Vitali B., Federici F., Massi M. and Brigidi P.. Identification and characterization of two Bifidobacterium proteins involved in the adhesin process to human intestinal epithelia cells. Selected for oral communication . 6° Convegno FISV, 30-3 Settembre 2004, Riva del Garda (TN), Italy.

27.  is speaker in the seminary “Lightcycler events 2003”, Dipartimento di Biochimica, Bologna. 18 Giugno 2003. Title: Studio di caratteristiche fenotipiche e genotipiche di Bifiodobacterium mediante real time PCR.

Congress abstracts

1.     Severgnini M, Consolandi C, Turroni S, Emmi G, Fiori J, Peano C, Biagi E, Grassi A, Rampelli S, Silvestri E, Centanni M, Gotti R, Emmi L, Brigidi P, De Bellis G, Prisco D, Candela M, D'Elios MM Microbiome signature of Behçet's syndrome patients. EMBL Heidelberg, il 10-12 Giugno, 2015.

2.     Clarissa C and S Turroni, S Rampelli, Centanni M, S Schnorr, Peano C, Severgnini M, Soverini M, A.N. Crittenden, A.G. Henry, G De Bellis, P Brigidi and M Candela. Enterocyte-associated microbiome of the Hadza hunter-gatherers6th Congress of European Microbiologists (FEMS 2015) Maastricht, the Netherlands, from June 7-11, 2015.

3.     E Biagi, M Candela, M Soverini, S Quercia, C Consolandi, M Severgnini, F Fallucca), M Pianesi, P Pozzilli, S Rampelli, S Turroni, P Brigidi. Modulation of gut microbiota dysbioses in type 2 diabetic patients by macrobiotic Ma-Pi 2 diet. 5 th International Human Microbiome Congress – IHMC. Luxemburg 1-4 April 2015.

4.     S Rampelli, M Soverini, SL. Schnorr, S Turroni, E Biagi, S Quercia, C Consolandi, AN. Crittenden, AG. Henry, P Brigidi and M Candela. Identification of new potential CAZymes in the gut microbiome from Hadza hunter gatherers. 5 th International Human Microbiome Congress – IHMC. Luxemburg 1-4 April 2015

5.     S Turroni, S Rampelli, C Consolandi, M Severgnini, C Peano, E Biagi, S Quercia, M Soverini, F Carbonero, G Bianconi, P Rettberg, F Canganella, P Brigidi, and M Candela. Temporal dynamics of gut microbiome in people sharing a confined environment, the ground space-simulation MARS500. 5 th International Human Microbiome Congress – IHMC. Luxemburg 1-4 April 2015

6.     S Schnorr, S Rampelli, S Turroni, E Biagi, C Consolandi, P Brigidi, A Crittenden, M Candela, A Henry Insights on the lipid metabolic potential of the gut microbiome in different human and animal groups. 5 th International Human Microbiome Congress – IHMC. Luxemburg 1-4 April 2015.

7.     C Nastasi, M Candela, P Brigidi, N Ødum, T Litman and A Woetmann. Anti-inflammatory action of short-chain fatty acids (SCFAs) on human monocyte-derived dendritic cells (DCs). Midwinter Conference 2015 Advances in Immunobiology January 17 - 21, 2015 Seefeld in Tirol, Austria.  

8.     Turroni S., Centanni M., Rampelli S., Biagi E., Quercia S., Consolandi C., Severgnini M., Brigidi P. and Candela M. Bifidobacterium animalis subsp. lactis BI07 modulates the TNF α -dependent unbalances of the enterocyte-associated intestinal microbiota fraction. Model Systems to Understand Microbiota-host Interactions. April 23-24, 2014. Durham University (Durham Business School), UK

9.     Consolandi C., Centanni M., Turroni S., Rampelli S.,Peano C., Severgnini M., Biagi E., De Bellis G., Brigidi P., Candela M., The probiotic strain B. animalis subsp. lactis BI07 differently modulates the inflammation dependent unbalances of the MUCOSA-ASSOCIATED INTESTINAL MICROBIOTA OF BREAST-FED INFANTS AND ADULTS. 7th Probiotics, Prebiotics & New Foods - Rome 8-10 September 2013.

10.  Basaglia G., Centanni M., Fiori J., Rampelli S., Turroni S., Biagi E., Candela M., Brigidi P., Gotti R., HEADSPACE SOLID-PHASE MICROEXTRACTION ANALYSIS OF SHORT CHAIN FATTY ACIDS IN FAECAL SAMPLES: APPLICATION TO COMPARATIVE METABOLOMIC STUDIES  OF THE HUMAN GUT MICROBIOTA. Analitica 2013, 15-19 Sept. 2013, Sestri Levante (GE), Italy.

11.  Biagi E., Nastasi C., Candela M., Zama D., Masetti R., Severgnini M., Brigidi P. and Pession A. Gut microbiota trajectories and immune system recovery in children who underwent to allogeneic hematopoietic stem cell transplantation (HSCT) . Microbiota and Immunity in Human Diseases. July 2013, Rome, Italy.

12.  Consolandi C. & Candela M., Peano C., Severgnini M., Biagi E., Rampelli S., Nastasi C., Zama D., Masetti R., Brigidi P. and Pession A. Gut microbiota trajectories and immune system recovery in children underwent to allogenic hematopoietics stem cell transplantation (HSCT). FEMS 2013. 5th congress of European Microbiologists, July 21-25 2013, Leipzing, Germany   

13.  Zama D., Masetti R., Candela M., Biagi E., Nastasi C., Vendemini F., Severgnini M., Franzoni M., Brigidi P., Prete A., Pession A. Gut microbiota trajectories and immune system recovery in children underwent to allogeneic haematopoietic stem cell transplantation (HSCT). 18th Congress of the European Hematology Association to be held in Stockholm, Sweden from June 13 - 16, 2013

14.  Zama D., Masetti R., Candela M., Biagi E., Nastasi C., Vendemini F., Severgnini M., Franzoni M., Brigidi P., Prete A., Pession A. The relationship between gut microbiota and immune system recovery in children who underwent allogeneic haematopoietic stem cell transplantation (HSCT). EBMT 2013. 7-10 April 2013, London, UK

15.  Spisni E., Valerii MC, Centanni M., Candela M., Scribano M., Campieri M. Essential oils as intestinal microbiota regulators in models of mice induced colitis. XXXV National Congress SINU
22-23 October 2012, Bologna, Italy

16.  Canganella F., Bianconi G., Di Mattia E., Rettberg P., Iylin V., Novikova N., Fani R., Brigidi P., Vitali B., Candela M. (2012). Experimental food microbiological issues related to human life support inside manned space modules: the MARS programme. In: International Scientific Conference on Probiotics and Prebiotics. Kosice, Slovakia, 12-14 June 2012, p. 1, KOSICE:IPC2012

17.  Centanni M., Turroni S., Rampelli S., Biagi E., Maccaferri S., Brigidi P., Candela M. Development of a pilot non-invasive ex vivo approach to study the impact of inflammation on the intestinal mucosa-associated microbial communities . 8th Joint INRA-Rowett Symposium on Gut Microbiology. Clermont-Ferrand (FRANCE), June 17-20, 2012.

18.  Centanni M., Candela M., Biagi E., Turroni S., Bellucci M., Musiani F., Bergmann S., Hammerschmidt S., Brigidi P.: Characterization of plasminogen binding mechanisms of the bifidobacterial receptor DnaK –National Congress of the Italian Society of General Microbiology and Microbial Biotechnology (SIMGBM) – September 21-23, 2011; Pisa (Italy).

19.  Biagi E., Candela M., Franceschi C., de Vos W., Brigidi P. The aging gut microbiota: a new perspective. National Congress of the Italian Society of General Microbiology and Microbial Biotechnology (SIMGBM) – September 21-23, 2011; Pisa (Italy).

20.  Candela M ., Turroni S., Severgnini M., Consolandi C., Peano C., Pession A., Brigidi P. Unbalances of the intestinal microbiota in atopic children. 4th Congress of European Microbiologists, FEMS 2011. 26-30 June, Geneva, Switzerland.

21.  Centanni M., Candela M., Biagi E., Fiori J., Musiani F., Orrico C., Bergmann S., Hammerschmidt S., Brigidi P.. Role of the bifidobacterial “moonlighting” proteins enolase and DnaK in the interaction process with the human host. 26° Convegno SIMGBM, 10-12 Giugno 2009, Spoleto, Italy.

22.  Candela M. , Biagi E., Severgnini M., Consolandi C., Castiglioni B., De Bellis G.. Development of a LDR-Universal array platform for the phylogenetic characterization of the Human Intestinal Microbiota. EFFO2008. November 4-9, Ljubljana, Slovenia

23.  Biagi E., Cruciani F., Turroni S., Candela M., Dipalo S., Vitali B. (2008). Modulation of gut microbiota by a synbiotic food. Food Production, Nutrition, Healthy Consumers. Delegate Manual. First European Food Congress. Ljubljana, Slovenia. 4-9 November 2008. (pp. P210). LJUBLJANA.

24.  Candela M. , Biagi E., Musiani F., Turroni S., Vitali B., Hammerschmidt S., Brigidi P.. Bifidobacterium lactis Enolase, surface localization and mechanism of interaction with human Plasminogen. Convegno FISV 2008. 24-27 Settembre.

25.  Fiori J., Gotti R., Candela M., Dipalo S., Brigidi P., Cavrini  V. INTERACTION BETWEEN BACTERIA AND HUMAN PROTEINS: A RAPID MALDI-TOF ANALYSIS. MASSA 2007. Settembre 2-5, Lucca, Italy.

26.  Turroni S., Dipalo S., Pugliese C., Candela M., Vitali B., Brigidi P. (2006). Oxalate-degrading activity in Lactobacillus. ATTI. 25° Congresso Nazionale della SIMGBM. Orvieto (TR). 8-10 giugno 2006. (pp. 123). ORVIETO (TR): SIMGBM.

27.  Pugliese C., Vitali B., Candela M., Turroni S., Donders G., Brigidi. P. (2006). PCR-DGGE characterization of vaginal microbial communities in healthy women and in patients with bacterial vaginosis and candidiasis. ATTI. 25° Congresso Nazionale della SIMGBM. Orvieto (TR). 8-10 giugno 2006. (pp. 87). ORVIETO (TR): SIMGBM.

28.  Candela M. , Vitali B., Federici F., Massi M. and Brigidi P.. Identification of two B. lactis proteins involved in the adhesin process to Caco 2 cell. First Congress IPSO, 27-29 May 2004, Verona , Italy

29.  Candela M. , Dal Piaz F., Vitali B., Federici F., Massi M.. Identificazione delle proteine coinvolte nell'adesione di Bifidobacterium A Caco 2 Cell. 5° Convegno FISV, 10-13 Ottobre 2003, Rimini (RN), Italy.

30.  Vitali B., Dal Piaz F., Federici F., Candela M., Massi M.. Analisi proteomica della Rifaximina-resistenza in Bifidobacterium. 5° Convegno FISV, 10-13 Ottobre 2003, Rimini (RN), Italy.

31.  Massi M., Vitali B., Federici F., Candela M., Brigidi P.. Identification method based on PCR Combined with automated ribotyping for tracking probiotic Lactobacillus strains colonizing the human gut and vigina” , 5° Convegno FISV, 10-13 Ottobre 2003, Rimini (RN), Italy.

32.  Federici F., Vitali B., Candela M., Massi M. e Brigidi P.. Caratterizzazione molecolare del gene Oxalyl-CoA decarbossilasi in Bifidobacterium lactis. 5° Convegno FISV, 10-13 Ottobre 2003, Rimini (RN), Italy.

33.  Candela M. , Vitali B., Federici F., Brigidi P., Matteuzzi D.. Sviluppo di un sistema di ricombinazione omologa a livello dell'operone ribosomale di Bifidobacterium. 4° Convegno FISV, 20-23 Settembre 2002, Riva del Garda (TN), Italy.

34.  Candela M. , Vitali B., Swennen E., Brigidi P.. Caratterizzazione dell'operone rrn in Bifidobacterium e determinazione del copy number mediante real-time PCR. 3° Convegno FISV, 21-25 Settembre 2001, Riva del Garda (TN), Italy.

35.  Vitali B., Candela M., Swennen E., Matteuzzi D.. Identificazione e quantificazione di bifidobatteri mediante PCR e real-time PCR: applicazioni industriali. 3° Convegno FISV, 21-25 Settembre 2001, Riva del Garda (TN), Italy.

 


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