INCEPTiON: Inhibition of respiratory ComplEx I and survival PaThways: a synthetic lethality approach for Ovarian caNcer (AIRC Fellowships for Italy 2019)
The main aim of this proposal is to study the functional relevance of the major signalling pathway activation in CI-defective ovarian cancer in vitro and in vivo in order to develop a combined pharmacological strategy to eradicate this severe cancer.