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Leonardo Calza

Associate Professor

Department of Medical and Surgical Sciences

Academic discipline: MED/17 Infectious Diseases

Research

Keywords: HIV and AIDS Opportunistic diseases Antiretroviral therapy HIV-associated comorbidities HBV and HCV CMV and EBV

Our scientific researches involve antiretroviral therapy for HIV infection, its metabolic adverse effects (dyslipidaemia and diabetes), and risk factors for cardiovascular diseases in HIV-infected subjects receiving antiretroviral treatment. Our studies concerne also therapeutic drug monitoring (TDM) of antiretroviral agents and lipid-lowering drugs (statins) in HIV-infected individuals, in the context of potential pharmacokinetic interactions between these compounds, and the risk of hepatotoxicity in HIV-HCV-coinfected subjects. Finally, we are assessing prevalence of HBV infection in HIV-positive patients and the correlation between HBV infection and progression to end stage liver disease.

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