Foto del docente

Laura Menotti

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/19 Microbiology


G. Campadelli-Fiume; C. De Giovanni; V. Gatta; P. Nanni; P.L. Lollini; L. Menotti, Rethinking herpes simplex virus: the way to oncolytic agents., «REVIEWS IN MEDICAL VIROLOGY», 2011, 21, pp. 213 - 226 [Scientific article]

Menotti L.; Nicoletti G.; Gatta V.; Croci S.; Landuzzi L.; De Giovanni C.; Nanni P.; Lollini P.L.; Campadelli-Fiume G., Inhibition of human tumor growth in mice by an oncolytic herpes simplex virus designed to target solely HER-2-positive cells., «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 2009, 106, pp. 9039 - 9044 [Scientific article]

Lollini P.L.; Menotti L.; De Giovanni C.; Campadelli-Fiume G.; Nanni P., Oncolytic herpes virus retargeted to HER-2., «CELL CYCLE», 2009, 8, pp. 2859 - 2860 [Scientific article]

Menotti L.; Cerretani A.; Hengel H.; Campadelli-Fiume G., Construction of a fully retargeted herpes simplex virus 1 recombinant capable of entering cells solely via human epidermal growth factor receptor 2, «JOURNAL OF VIROLOGY», 2008, 82, pp. 10153 - 10161 [Scientific article]

Patent n. Domanda n° PCT/IT2008/000358. Depositato il 29-5-2008, Herpes simplex virus (HSV) with modified tropism, uses and process of preparation thereof..

G. Campadelli-Fiume; L. Menotti, Entry of alphaherpesviruses into the cell, in: Human Herpesviruses : Biology, Therapy and Immunoprophylaxis, CAMBRIDGE, Cambridge University Press, 2007, pp. 93 - 111 [Chapter or essay]

Campadelli-Fiume G.; Amasio M.; Avitabile E.; Cerretani A.; Forghieri C.; Gianni T; Menotti L., The multipartite system that mediates entry of herpes simplex virus into the cell, «REVIEWS IN MEDICAL VIROLOGY», 2007, 17, pp. 313 - 326 [Scientific article]

Menotti L.; Cerretani A.; Campadelli-Fiume G., A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptors., «JOURNAL OF VIROLOGY», 2006, 80, pp. 5531 - 5539 [Scientific article]

GIANNI T.; MENOTTI L.; CAMPADELLI-FIUME G., A heptad repeat in herpes simplex virus-1 gH, located downstream of the α-helix with attributes of a fusion peptide, is critical for virus entry and fusion., «JOURNAL OF VIROLOGY», 2005, 79, pp. 7042 - 7049 [Scientific article]


GIANNI T.; CAMPADELLI-FIUME G.; MENOTTI L., Entry of herpes simplex virus mediated by chimeric forms of nectin1 retargeted to endosomes or to lipid rafts occurs through acidic endosomes., «JOURNAL OF VIROLOGY», 2004, 78, pp. 12268 - 12276 [Scientific article]

COCCHI F.; MENOTTI L.; DI NINNI V.; LOPEZ M.; CAMPADELLI-FIUME G., The herpes simplex virus JMP mutant enters receptor-negative J cells through a novel pathway independent of the known receptors nectin1, HveA, and nectin2., «JOURNAL OF VIROLOGY», 2004, 78, pp. 4720 - 4729 [Scientific article]

COCCHI F.; FUSCO D.; MENOTTI L.; GIANNI T.; EISENBERG R.J.; COHEN G.H.; CAMPADELLI-FIUME G., The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry., «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 2004, 101, pp. 7445 - 7450 [Scientific article]

Bertucci C.; Cimitan S.; Menotti L., Optical biosensor analysis in studying herpes simplex virus glycoprotein D binding to target nectin1 receptor, «JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS», 2003, 32, pp. 697 - 706 [Scientific article]

Menotti L.; Cocchi F.; Campadelli-Fiume G., Critical residues in the CC′ ridge of the human nectin1 receptor V domain enable herpes simplex virus entry into the cell and act synergistically with the downstream region, «VIROLOGY», 2002, 301, pp. 6 - 12 [Scientific article]

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