Prof. Giusti’s scientific activity focuses on the fields of cellular biochemistry and protein biochemistry. The primary aim of her research is the investigation of proteins and their functional characteristics through proteomic approaches and the study of protein–protein interactions.
Her main research line concerns endocrine diseases, cancer, autoimmune disorders, and diabetes, with the objective of elucidating pathophysiological mechanisms and identifying potential diagnostic and therapeutic biomarkers. Her recent interests include the study of post‑translational modifications—particularly acetylation—in type I and type II diabetes. Within the human research domain, she is also currently investigating acute stress responses using saliva as a biological matrix to detect molecular changes.
Another research line focuses on the action of nutraceuticals in counteracting oxidative stress and inflammation in in vitro cellular models of neurodegeneration and inflammation, as well as in in vivo models, employing a proteomic approach.
