Foto del docente

Jessica Marinello

Associate Professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/11 Molecular Biology


Renée Concetta Duardo , Jessica Marinello , Marco Russo , Sara Morelli , Simona Pepe , Federico Guerra , Belén Gómez-González , Andrés Aguilera , Giovanni Capranico, Human DNA topoisomerase I poisoning causes R loop-mediated genome instability attenuated by transcription factor IIS, «SCIENCE ADVANCES», 2024, 10, pp. 1 - 21 [Scientific article]

Miglietta, Giulia; Marinello, Jessica; Capranico, Giovanni, Immunofluorescence microscopy of G-quadruplexes and R-loops, in: Methods in Enzymology, Orlando, Academic Press, 2024, pp. 1 - 16 (METHODS IN ENZYMOLOGY) [Chapter or essay]

Geraud M.; Cristini A.; Salimbeni S.; Bery N.; Jouffret V.; Russo M.; Ajello A.C.; Fernandez Martinez L.; Marinello J.; Cordelier P.; Trouche D.; Favre G.; Nicolas E.; Capranico G.; Sordet O., TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks, «CELL REPORTS», 2024, 43, pp. 1 - 32 [Scientific article]

Marzano S.; Miglietta G.; Morigi R.; Marinello J.; Arleo A.; Procacci M.; Locatelli A.; Leoni A.; Pagano B.; Randazzo A.; Amato J.; Capranico G., Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 12055 - 12067 [Scientific article]Open Access

Jessica Marinello, Giovanni Capranico, Highly Purified Top1-Bound DNA Fragments, in: Methods in Molecular Biology, New York, Humana Press Inc., 2022, pp. 203 - 213 (METHODS IN MOLECULAR BIOLOGY) [Chapter or essay]

Miglietta G.; Marinello J.; Russo M.; Capranico G., Ligands stimulating antitumour immunity as the next G-quadruplex challenge, «MOLECULAR CANCER», 2022, 21, pp. 180 - 194 [Scientific article]Open Access

Jessica Marinello, Andrea Arleo, Marco Russo, Maria Delcuratolo, Francesca Ciccarelli, Yves Pommier, Giovanni Capranico., Topoisomerase I poison-triggered immune gene activation is markedly reduced in human small-cell lung cancers by impairment of the cGAS/STING pathway, «BRITISH JOURNAL OF CANCER», 2022, 127, pp. 1214 - 1225 [Scientific article]Open Access

De Magis, Alessio; Manzo, Stefano G.; Russo, Marco; Marinello, Jessica; Morigi, Rita; Sordet, Olivier; Capranico, Giovanni*, DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells, «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 2019, 116, pp. 816 - 825 [Scientific article]

Cristini A.; Ricci G.; Britton S.; Salimbeni S.; Huang S.-Y.N.; Marinello J.; Calsou P.; Pommier Y.; Favre G.; Capranico G.; Gromak N.; Sordet O., Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks, «CELL REPORTS», 2019, 28, pp. 3167 - 3181 [Scientific article]Open Access

Marinello, Jessica; Delcuratolo, Maria; Capranico, Giovanni, Anthracyclines as Topoisomerase II Poisons: From Early Studies to New Perspectives, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2018, 19, Article number: 3480 , pp. 1 - 18 [Scientific article]Open Access

Manzo, Stefano G.; Hartono, Stella R.; Sanz, Lionel A.; Marinello, Jessica; De Biasi, Sara; Cossarizza, Andrea; Capranico, Giovanni*; Chedin, Frederic, DNA Topoisomerase I differentially modulates R-loops across the human genome, «GENOME BIOLOGY», 2018, 19, Article number: 100 , pp. 1 - 18 [Scientific article]Open Access

Amato, Jussara; Pagano, Alessia; Cosconati, Sandro; Amendola, Giorgio; Fotticchia, Iolanda; Iaccarino, Nunzia; Marinello, Jessica; De Magis, Alessio; Capranico, Giovanni; Novellino, Ettore; Pagano, Bruno; Randazzo, Antonio, Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: A new opportunity in the targeting of G-rich DNA structures?, «BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS», 2017, Volume 1861, pp. 1271 - 1280 [Scientific article]

Miglietta, Giulia; Cogoi, Susanna; Marinello, Jessica; Capranico, Giovanni; Tikhomirov, Alexander S.; Shchekotikhin, Andrey; Xodo, Luigi E.*, RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation, «JOURNAL OF MEDICINAL CHEMISTRY», 2017, 60, pp. 9448 - 9461 [Scientific article]

Capranico, Giovanni; Marinello, Jessica; Chillemi, Giovanni, Type I DNA Topoisomerases, «JOURNAL OF MEDICINAL CHEMISTRY», 2017, 60, pp. 2169 - 2192 [Scientific article]

Marinello, Jessica; Bertoncini, Stefania; Aloisi, Iris; Cristini, Agnese; Tagliazucchi, Guidantonio Malagoli; Forcato, Mattia; Sordet, Olivier; Capranico, Giovanni, Dynamic effects of topoisomerase i inhibition on R-loops and short transcripts at active promoters, «PLOS ONE», 2016, 11, Article number: e0147053 , pp. 1 - 18 [Scientific article]

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