Foto del docente

Jessica Marinello

Ricercatrice a tempo determinato tipo b) (senior)

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: BIO/11 BIOLOGIA MOLECOLARE

Pubblicazioni

De Magis, Alessio; Manzo, Stefano G.; Russo, Marco; Marinello, Jessica; Morigi, Rita; Sordet, Olivier; Capranico, Giovanni*, DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells, «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 2019, 116, pp. 816 - 825 [articolo]

Cristini A.; Ricci G.; Britton S.; Salimbeni S.; Huang S.-Y.N.; Marinello J.; Calsou P.; Pommier Y.; Favre G.; Capranico G.; Gromak N.; Sordet O., Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks, «CELL REPORTS», 2019, 28, pp. 3167 - 3181 [articolo]Open Access

Marinello, Jessica; Delcuratolo, Maria; Capranico, Giovanni, Anthracyclines as Topoisomerase II Poisons: From Early Studies to New Perspectives, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2018, 19, pp. 1 - 18 [articolo]Open Access

Manzo, Stefano G.; Hartono, Stella R.; Sanz, Lionel A.; Marinello, Jessica; De Biasi, Sara; Cossarizza, Andrea; Capranico, Giovanni*; Chedin, Frederic, DNA Topoisomerase I differentially modulates R-loops across the human genome, «GENOME BIOLOGY», 2018, 19, pp. 1 - 18 [articolo]Open Access

Amato, Jussara; Pagano, Alessia; Cosconati, Sandro; Amendola, Giorgio; Fotticchia, Iolanda; Iaccarino, Nunzia; Marinello, Jessica; De Magis, Alessio; Capranico, Giovanni; Novellino, Ettore; Pagano, Bruno; Randazzo, Antonio, Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: A new opportunity in the targeting of G-rich DNA structures?, «BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS», 2017, Volume 1861, pp. 1271 - 1280 [articolo]

Miglietta, Giulia; Cogoi, Susanna; Marinello, Jessica; Capranico, Giovanni; Tikhomirov, Alexander S.; Shchekotikhin, Andrey; Xodo, Luigi E., RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation, «JOURNAL OF MEDICINAL CHEMISTRY», 2017, 60, pp. 9448 - 9461 [articolo]

Capranico, Giovanni; Marinello, Jessica; Chillemi, Giovanni, Type I DNA Topoisomerases, «JOURNAL OF MEDICINAL CHEMISTRY», 2017, 60, pp. 2169 - 2192 [articolo]

Marinello, Jessica; Bertoncini, Stefania; Aloisi, Iris; Cristini, Agnese; Tagliazucchi, Guidantonio Malagoli; Forcato, Mattia; Sordet, Olivier; Capranico, Giovanni, Dynamic effects of topoisomerase i inhibition on R-loops and short transcripts at active promoters, «PLOS ONE», 2016, 11, pp. 1 - 18 [articolo]

Malgorzata N. Drwal;Jessica Marinello;Stefano G. Manzo;Laurence P. G. Wakelin;Giovanni Capranico;Renate Griffith, Novel DNA Topoisomerase IIα Inhibitors from Combined Ligand- and Structure-Based Virtual Screening, «PLOS ONE», 2014, 9, pp. 1 - 16 [articolo]

D. Bertozzi;J. Marinello;S. G. Manzo;F. Fornari;L. Gramantieri;G. Capranico, The Natural Inhibitor of DNA Topoisomerase I, Camptothecin, Modulates HIF-1 alpha Activity by Changing miR Expression Patterns in Human Cancer Cells, «MOLECULAR CANCER THERAPEUTICS», 2014, 13, pp. 239 - 248 [articolo]

J. Marinello;G. Chillemi;S. Bueno;S. G. Manzo;G. Capranico, Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation, «NUCLEIC ACIDS RESEARCH», 2013, 41, pp. 10110 - 10123 [articolo]

Petronzi C; Festa M; Peduto A; Castellano M; Marinello J; Massa A; Capasso A; Capranico G; La Gatta A; De Rosa M; Caraglia M; Filosa R., Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation., «JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH», 2013, 32, pp. 1 - 11 [articolo]

Fornari F.; Milazzo M.; Chieco P.; Negrini M.; Marasco E.; Capranico G.; Mantovani V.; Marinello J.; Sabbioni S.; Callegari E.; Cescon M.; Ravaioli M.; Croce C.M.; Bolondi L.; Gramantieri L., In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2., «JOURNAL OF PATHOLOGY», 2012, 227, pp. 275 - 285 [articolo]

Manzo S. G.; Z.-L. Zhou; Y.-Q. Wang; J. Marinello; J.-X. He; Y.-C. Li; J. Ding; G. Capranico; Z.-H. Miao, Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II, «CANCER RESEARCH», 2012, 72, pp. 5363 - 5373 [articolo]

Capranico G; Baranello L; Bertozzi D; Marinello J, Transcriptional Stress by Camptothecin: Mechanisms and Implications for the Drug Antitumor Activity, in: DNA Topoisomerases and Cancer, NEW YORK, Humana Press - Springer Science, 2012, pp. 309 - 324 (CANCER DRUG DISCOVERY AND DEVELOPMENT) [capitolo di libro]

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