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Jessica Marinello

Professoressa associata

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: BIO/11 BIOLOGIA MOLECOLARE

Pubblicazioni

Malgorzata N. Drwal;Jessica Marinello;Stefano G. Manzo;Laurence P. G. Wakelin;Giovanni Capranico;Renate Griffith, Novel DNA Topoisomerase IIα Inhibitors from Combined Ligand- and Structure-Based Virtual Screening, «PLOS ONE», 2014, 9, Article number: e114904, pp. 1 - 16 [articolo]

D. Bertozzi;J. Marinello;S. G. Manzo;F. Fornari;L. Gramantieri;G. Capranico, The Natural Inhibitor of DNA Topoisomerase I, Camptothecin, Modulates HIF-1 alpha Activity by Changing miR Expression Patterns in Human Cancer Cells, «MOLECULAR CANCER THERAPEUTICS», 2014, 13, pp. 239 - 248 [articolo]

J. Marinello;G. Chillemi;S. Bueno;S. G. Manzo;G. Capranico, Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation, «NUCLEIC ACIDS RESEARCH», 2013, 41, pp. 10110 - 10123 [articolo]

Petronzi C; Festa M; Peduto A; Castellano M; Marinello J; Massa A; Capasso A; Capranico G; La Gatta A; De Rosa M; Caraglia M; Filosa R., Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation., «JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH», 2013, 32, Article number: 24, pp. 1 - 11 [articolo]

Fornari F.; Milazzo M.; Chieco P.; Negrini M.; Marasco E.; Capranico G.; Mantovani V.; Marinello J.; Sabbioni S.; Callegari E.; Cescon M.; Ravaioli M.; Croce C.M.; Bolondi L.; Gramantieri L., In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2., «JOURNAL OF PATHOLOGY», 2012, 227, pp. 275 - 285 [articolo]

Manzo S. G.; Z.-L. Zhou; Y.-Q. Wang; J. Marinello; J.-X. He; Y.-C. Li; J. Ding; G. Capranico; Z.-H. Miao, Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II, «CANCER RESEARCH», 2012, 72, pp. 5363 - 5373 [articolo]

Capranico G; Baranello L; Bertozzi D; Marinello J, Transcriptional Stress by Camptothecin: Mechanisms and Implications for the Drug Antitumor Activity, in: DNA Topoisomerases and Cancer, NEW YORK, Humana Press - Springer Science, 2012, pp. 309 - 324 (CANCER DRUG DISCOVERY AND DEVELOPMENT) [capitolo di libro]

Bertozzi Davide; Iurlaro Raffaella; Sordet Olivier; Marinello Jessica; Zaffaroni Nadia; Capranico Giovanni, Characterization of novel antisense HIF-1α transcripts in human cancers, «CELL CYCLE», 2011, 10, pp. 3189 - 3197 [articolo]

Ricci A; Marinello J; Bortolus M; Sanchez A; Grandas A; Pedroso E; Pommier Y; Capranico G; Maniero AL; Zagotto G., Electron Paramagnetic Resonance (EPR) Study of Spin-Labeled Camptothecin Derivatives: A Different Look of the Ternary Complex., «JOURNAL OF MEDICINAL CHEMISTRY», 2011, 54, pp. 1003 - 1009 [articolo]

G. Capranico; J. Marinello; L. Baranello, Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: Implications for physiological and therapeutic modulation of enzyme activity., «BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER», 2010, 1806(2), pp. 240 - 250 [articolo]

Tumiatti V; Milelli A ; Minarini A; Micco M; Gasperi-Campani A; Roncuzzi L; Baiocchi D; Marinello J; Capranico G; Zini M; Stefanelli C; Melchiorre C, DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT, «JOURNAL OF MEDICINAL CHEMISTRY», 2009, 52, pp. 7873 - 7877 [articolo]

Marinello J; Marchand C; Mott BT; Bain A; Thomas CJ; Pommier Y, Comparison of raltegravir and elvitegravir on HIV-1 integrase catalytic reactions and on a series of drug-resistant integrase mutants, «BIOCHEMISTRY», 2008, 47, pp. 9345 - 9354 [articolo]

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