Foto del docente

Isabella Orienti

Professoressa ordinaria

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHIM/09 FARMACEUTICO TECNOLOGICO APPLICATIVO

Pubblicazioni

Orienti I.; Cripe T.P.; Currier M.A.; Cavallari C.; Teti G.; Falconi M., A cationic nanomicellar complex of the quaternary amphiphilic amine rc16+ with fenretinide as a new multitasking system for antitumor therapy, «CURRENT DRUG DELIVERY», 2019, 16, pp. 807 - 817 [articolo]

Orienti I.; Francescangeli F.; De Angelis M.L.; Fecchi K.; Bongiorno-Borbone L.; Signore M.; Peschiaroli A.; Boe A.; Bruselles A.; Costantino A.; Eramo A.; Salvati V.; Sette G.; Contavalli P.; Zolla L.; Oki T.; Kitamura T.; Spada M.; Giuliani A.; Baiocchi M.; La Torre F.; Melino G.; Tartaglia M.; De Maria R.; Zeuner A., A new bioavailable fenretinide formulation with antiproliferative, antimetabolic, and cytotoxic effects on solid tumors, «CELL DEATH & DISEASE», 2019, 10, Article number: 529, pp. 529 - 548 [articolo]Open Access

Orienti I.; Nguyen F.; Guan P.; Kolla V.; Calonghi N.; Farruggia G.; Chorny M.; Brodeur G.M., A novel nanomicellar combination of fenretinide and lenalidomide shows marked antitumor activity in a neuroblastoma xenograft model, «DRUG DESIGN, DEVELOPMENT AND THERAPY», 2019, 13, pp. 4305 - 4319 [articolo]Open Access

Orienti I.; Salvati V.; Sette G.; Zucchetti M.; Bongiorno-Borbone L.; Peschiaroli A.; Zolla L.; Francescangeli F.; Ferrari M.; Matteo C.; Bello E.; Di Virgilio A.; Falchi M.; De Angelis M.L.; Baiocchi M.; Melino G.; De Maria R.; Zeuner A.; Eramo A., A novel oral micellar fenretinide formulation with enhanced bioavailability and antitumour activity against multiple tumours from cancer stem cells, «JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH», 2019, 38, Article number: 373, pp. 373 - 390 [articolo]Open Access

Focaroli, Stefano; Teti, Gabriella; Salvatore, Viviana; Orienti, Isabella; Falconi, Mirella, Calcium/Cobalt Alginate Beads as Functional Scaffolds for Cartilage Tissue Engineering, «STEM CELLS INTERNATIONAL», 2016, 2016, Article number: 2030478, pp. 1 - 12 [articolo]Open Access

Orienti, Isabella; Falconi, Mirella; Teti, Gabriella; Currier, Mark A.; Wang, Jiang; Phelps, Mitch; Cripe, Timothy P., Preparation and Evaluation of a Novel Class of Amphiphilic Amines as Antitumor Agents and Nanocarriers for Bioactive Molecules, «PHARMACEUTICAL RESEARCH», 2016, 33, pp. 2722 - 2735 [articolo]

Pignatta S;Orienti I;Falconi M;Teti G;Arienti C;Medri L;Zanoni M;Carloni S;Zoli W;Amadori D;Tesei A, Albumin nanocapsules containing fenretinide: pre-clinical evaluation of cytotoxic activity in experimental models of human non-small cell lung cancer., «NANOMEDICINE», 2015, 11, pp. 263 - 273 [articolo]

Di Francesco, A.M; Cusano, G.; Franzese, O.; Orienti, I.; Falconi, M.; Vesci, L.; Riccardi, R., Resistance to the atypical retinoid ST1926 in SK-N-AS cells selected the subline rAS-ST with enhanced sensitivity to ATRA mediated by not conventional mechanisms: DNA damage, G2 accumulation and late telomerase inhibition, «TOXICOLOGY IN VITRO», 2015, 29, pp. 1628 - 1638 [articolo]

Durante S; Orienti I; Teti G; Salvatore V; Focaroli S; Tesei A; Pignatta S; Falconi M., Anti-tumor activity of fenretinide complexed with human serum albumin in lung cancer xenograft mouse model., «ONCOTARGET», 2014, 5, pp. 4811 - 4820 [articolo]

Falconi M;Focaroli S;Teti G;Salvatore V;Durante S;Nicolini B;Orienti I, Novel PLA microspheres with hydrophilic and bioadhesive surfaces for the controlled delivery of fenretinide, «JOURNAL OF MICROENCAPSULATION», 2014, 31, pp. 41 - 48 [articolo]

Falconi M; Salvatore V; Teti G; Focaroli S; Durante S; Nicolini B; Mazzotti A; Orienti I., Gelatin crosslinked with dehydroascorbic acid as a novel scaffold for tissue regeneration with simultaneous antitumor activity., «BIOMEDICAL MATERIALS», 2013, 8, pp. 1 - 8 [articolo]

Stefano Focaroli; Viviana Salvatore; Silvia Bolzani; Pietro Gobbi; Alessandra Ruggeri; Isabella Orienti, Antitumor activity of fenretinide encapsulated in novel based PLA microspheres, in: IJAE, 2012, pp. 73 - 73 (atti di: 66°CONGRESSO SOCIETA' ITALIANA ANATOMIA E ISTOLOGIA, PISTOIA, SETTEMBRE 2012) [atti di convegno-abstract]

Viviana Salvatore; Isabella Orienti; Stefano Focaroli; Sandra Durante; Monica Mattioli Belmonte; Mirella Falconi, Cell adhesion and proliferation on gelatin-ascorbic acid scaffold, in: Italian Journal of Anatomy and Embryology, «ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY», 2012, 117, pp. 168 - 168 (atti di: 66° CONGRESSO NAZIONALE DELLA SOCIETA' ITALIANA DI ANATOMIA E ISTOLOGIA, PISTOIA, 20 al 23 settembre 2012) [atti di convegno-abstract]

Viviana Salvatore; Isabella Orienti; Stefano Focaroli; Sandra Durante; Monica Mattioli Belmonte and Mirella Falconi, Cell adhesion and proliferation on gelatin-ascorbic acid scaffold, «ITALIAN JOURNAL OF ANATOMY AND EMBRYOLOGY», 2012, 117, pp. 168 - 168 [abstract]

Carosio R.; Pistoia V.; Orienti I.; Formelli F.; Cavadini E.; Mangraviti S.; Montaldo P.G.; Ognio E.; Emionite L.; Zuccari G., Enhanced anti-neuroblastoma activity of a fenretinide complexed form after intravenous administration, «JOURNAL OF PHARMACY AND PHARMACOLOGY», 2012, 64(2), pp. 36 - 228 [articolo]