Radi M.; Falchi F.; Garbelli A.; Samuele A.; Bernardo V.; Paolucci S.; Baldanti F.; Schenone S.; Manetti F.; Maga G.; Botta M., Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors, «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2012, 22, pp. 2094 - 2098 [Scientific article]
Giovanni Maga, Anna Garbelli, Marco Radi, Federico Falchi, Alberta Samuele, Stefania Paolucci, Fausto Baldanti, Fabrizio Manetti, Sandra Beermann, Ursula Dietrich, Maurizio Botta, Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach, «RETROVIROLOGY», 2012, 9, pp. 1 - 1 [Scientific article]
Patent n. WO/2011/039735, COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF.
Corradi V; Mancini M; Santucci MA; Carlomagno T; Sanfelice D; Mori M; Vignaroli G; Falchi F; Manetti F; Radi M; Botta M, Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case, «BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS», 2011, 21, pp. 6867 - 6871 [Scientific article]
Schenone S.; Brullo C.; Musumeci F.; Biava M.; Falchi F.; Botta M., Fyn kinase in brain diseases and cancer: The search for inhibitors, «CURRENT MEDICINAL CHEMISTRY», 2011, 18, pp. 2921 - 2942 [Scientific article]
Arioli F.; Borrelli S.; Colombo F.; Falchi F.; Filippi I.; Crespan E.; Naldini A.; Scalia G.; Silvani A.; Maga G.; Carraro F.; Botta M.; Passarella D., N-[2-methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a Scaffold for the synthesis of inhibitors of Bcr-Abl, «CHEMMEDCHEM», 2011, 6, pp. 2009 - 2018 [Scientific article]
Patent n. WO/2011/101787, NON PEPTIDIC 14-3-3 INHIBITORS AND THE USE THEREOF.
Garbelli A.; Radi M.; Falchi F.; Beermann S.; Zanoli S.; Manetti F.; Dietrich U.; Botta M.; Maga G., Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication, «CURRENT MEDICINAL CHEMISTRY», 2011, 18, pp. 3015 - 3027 [Scientific article]
Maga G.; Falchi F.; Radi M.; Botta L.; Casaluce G.; Bernardini M.; Irannejad H.; Manetti F.; Garbelli A.; Samuele A.; Zanoli S.; Este J.A.; Gonzalez E.; Zucca E.; Paolucci S.; Baldanti F.; DeRijck J.; Debyser Z.; Botta M., Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation, «CHEMMEDCHEM», 2011, 6, pp. 1371 - 1389 [Scientific article]
Radi M.; Crespan E.; Falchi F.; Bernardo V.; Zanoli S.; Manetti F.; Schenone S.; Maga G.; Botta M., Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: From docking false positives to ATP-noncompetitive inhibitors, «CHEMMEDCHEM», 2010, 5, pp. 1226 - 1231 [Scientific article]
Giovanni Maga, Federico Falchi, Anna Garbelli, Marco Radi, Stefania Paolucci, Fausto Baldanti, Maurizio Botta, Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase, «RETROVIROLOGY», 2010, 7, pp. 1 - 1 [Scientific article]
Falchi F.; Manetti F.; Carraro F.; Naldini A.; Maga G.; Crespan E.; Schenone S.; Bruno O.; Brullo C.; Botta M., 3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors, «CHEMMEDCHEM», 2009, 4, pp. 976 - 987 [Scientific article]
Dreassi E.; Zizzari A.T.; Falchi F.; Schenone S.; Santucci A.; Maga G.; Botta M., Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2009, 44, pp. 3712 - 3717 [Scientific article]
Radi M; Crespan E; Botta G; Falchi F; Maga G; Manetti F; Corradi V; Mancini M; Santucci MA; Schenone S; Botta M., Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents., «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2008, 18, pp. 1207 - 1211 [Scientific article]
Manetti F.; Falchi F.; Crespan E.; Schenone S.; Maga G.; Botta M., N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds, «BIOORGANIC & MEDICINAL CHEMISTRY LETTERS», 2008, 18, pp. 4328 - 4331 [Scientific article]
