EDUCATION
2002 University of Pisa: Graduation Degree in Chemistry, Organic Chemistry.
2006 University of Siena: Masters in “Drug Design and Synthesis”.
2010 La Sapienza University of Rome: Dottorato di Ricerca in Scienze Farmaceutiche.
RESEARCH EXPERIENCE
2010–2011 Post-Doc at the University of Siena. Structure-based virtual screening and hit to lead optimization to identify new anticancer and antiviral drugs targeting: the 14-3-3/Abl protein-protein interaction; the Fyn, Hck, Abl and Src kinases;DDX3 helicase.
2011–2013 Post-Doc at Cinbo (Consorzio Interuniversitario Nazionale per la Bio-Oncologia). Structure-based virtual screening and hit to lead optimization to identify new anticancer drugs targeting: the VHL/ElongineC protein-protein interaction; theVHL/Hif2α protein-protein interaction.
2013 Post-Doc at PharmaMab. Structure-based virtual screening and hit to lead optimization to identify new anticancer drugs targeting the Hif2α PAS domain heterodimerization.
2013-2018 Post-Doc at Istituto Italiano di tecnologia. Structure-based virtual screening and hit to lead optimization to identify new anticancer drugs targeting: the Rad51/BRCA protein-protein interaction, the MDM2/p53 protein-protein interaction and other targets.
2018-2021 Senior researcher at Molecular Horizon di Bettona (PG).
COMPETENCES
Virtual screening, Hit to Lead optimization, QSAR, 3DQSAR, ADMET prediction, Molecular Docking, Molecular dynamics, Protein-Protein interaction.
