Education
Degree in Pharmaceutical Chemistry and Technology University of Bologna
Professional Experience:
2003: Assistant Professor of Medicinal Chemistry University of Bologna
2013: National Academic Qualification as Associate Professor of Medicinal Chemistry
2020: Associate Professor of Medicinal Chemistry, University of Bologna
Research Interests:
Design and synthesis of small molecules as potential therapeutic agents or tools for the study and characterization of biological processes. Using an appropriate functionalization of scaffolds related to natural products, as privileged structures, several bioactive chemical entities have been developed. These compounds proved to effectively interact with some biological targets involved in the onset and development of cancer, neurodegenerative disorders (Alzheimer's and Parkinson), parasitic (malaria, leishmaniasis, trypanosomiasis), and infective diseases. In this context, several multi-target agents have were identified as therapeutic candidates to treat multifactorial maladies.
These activities have resulted in the publication of 82 original papers and review articles in international journals indexed by Scopus .
Professional Experiences:
1995-2003: Grant Indena S.p.A,
University of Bologna. Title of the project: “New natural antitumor
and cancer chemopreventive agents: synthesis of chalcones and
flavones”.
2001:
Grant for abroad training period (Indena S.p.A), University of
Stony Brook, N.Y.
2003:-
Assistant Professor, Medicinal Chemistry, University of Bologna
2006-2007: Scientific
collaboration in projects with Indena S.p.A , entitled “Bioactive
natural products“
Professional Society Memberships:
Società Chimica Italiana, SCI - Division of Medicinal
Chemistry
Teaching Activities (2004-Present):
A.A.
2005-/06:
Natural Compounds Extraction
A.A.
2006/07:
Natural Compounds Analysis I
A.A. 2006/0:
Medicinal and Toxicological Chemistry II, School of Specialization
in Hospital Pharmacy (6 hours course)
A.A.
2007/08:
Natural Compounds Extraction
A.A.
2008/09:
Natural Compounds Analysis I
A.A.
2009/10-2016/18:
Analysis of Phytoderivatives II
AA 2018/19-to date: Experimental Methodologies for Drug Preparation
To date, he is author or co-author of 96 scientific articles published in international peer-reviewed journals, 51 of which have been published in the last 10 years.
National and International Collaborations:
Prof. Vincenza Andrisano Dipartimento di Scienze
Farmaceutiche – Università di Bologna; Prof. Enrica Bosisio
Dipartimento di Scienze Farmacologiche – Università di Milano;
Dr Maria Carrara Dipartimento di Farmacologia ed
Anestesiologia, Università di Padova; Dr. Andrea Cavalli
Dipartimento di Scienze Farmaceutiche– Università di Bologna;
Prof. Rolf W. Hartmann Saarland University – Saarbrücken
(D); Indena –Holding S.p.A, Milano; Prof. Remo
Perozzo School of Pharmaceutical Sciences – University of
Geneva (CH); Prof. Paul Michels Christian De Duve Institute
– Brussels (B); Dott. Franco Zunino Fondazione IRCCS –
Istituto Nazionale Tumori, Milano; Dr Reto
Brun Swiss Tropical & Health Institute, Basel (CH);
Andrea Tarozzi Dipartimento di Farmacologia –
Università di Bologna
