Foto del docente

Emanuele Paci

Professore associato

Dipartimento di Fisica e Astronomia "Augusto Righi"

Settore scientifico disciplinare: FIS/07 FISICA APPLICATA (A BENI CULTURALI, AMBIENTALI, BIOLOGIA E MEDICINA)

Pubblicazioni

Brockwell D.J.; Beddard G.S.; Paci E.; West D.K.; Olmsted P.D.; Smith D.A.; Radford S.E., Mechanically unfolding the small, topologically simple protein L, «BIOPHYSICAL JOURNAL», 2005, 89, pp. 506 - 519 [articolo]

Forman J.R.; Qamar S.; Paci E.; Sandford R.N.; Clarke J., The remarkable mechanical strength of polycystin-1 supports a direct role in mechanotransduction, «JOURNAL OF MOLECULAR BIOLOGY», 2005, 349, pp. 861 - 871 [articolo]

Paci E.; Lindorff-Larsen K.; Dobson C.M.; Karplus M.; Vendruscolo M., Transition state contact orders correlate with protein folding rates, «JOURNAL OF MOLECULAR BIOLOGY», 2005, 352, pp. 495 - 500 [articolo]

Lindorff-Larsen K.; Vendruscolo M.; Paci E.; Dobson C.M., Transition states for protein folding have native topologies despite high structural variability, «NATURE STRUCTURAL & MOLECULAR BIOLOGY», 2004, 11, pp. 443 - 449 [articolo]

Paci E.; Cavalli A.; Vendruscolo M.; Caflisch A., Analysis of the distributed computing approach applied to the folding of a small β peptide, «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 2003, 100, pp. 8217 - 8222 [articolo]

Brockwell D.J.; Paci E.; Zinober R.C.; Beddard G.S.; Olmsted P.D.; Smith D.A.; Perham R.N.; Radford S.E., Pulling geometry defines the mechanical resistance of a β-sheet protein, «NATURE STRUCTURAL BIOLOGY», 2003, 10, pp. 731 - 737 [articolo]

Vendruscolo M.; Paci E.; Dobson C.M.; Karplus M., Rare Fluctuations of Native Proteins Sampled by Equilibrium Hydrogen Exchange, «JOURNAL OF THE AMERICAN CHEMICAL SOCIETY», 2003, 125, pp. 15686 - 15687 [articolo]

Paci E.; Clarke J.; Steward A.; Vendruscolo M.; Karplus M., Self-consistent determination of the transition state for protein folding: Application to a fibronectin type III domain, «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 2003, 100, pp. 394 - 399 [articolo]

Vendruscolo M.; Paci E.; Karplus M.; Dobson C.M., Structures and relative free energies of partially folded states of proteins, «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 2003, 100, pp. 14817 - 14821 [articolo]

Fowler S.B.; Best R.B.; Toca Herrera J.L.; Rutherford T.J.; Steward A.; Paci E.; Karplus M.; Clarke J., Mechanical unfolding of a titin Ig domain: Structure of unfolding intermediate revealed by combining AFM, molecular dynamics simulations, NMR and protein engineering, «JOURNAL OF MOLECULAR BIOLOGY», 2002, 322, pp. 841 - 849 [articolo]

Vendruscolo M.; Dokholyan N.V.; Paci E.; Karplus M., Small-world view of the amino acids that play a key role in protein folding, «PHYSICAL REVIEW E, STATISTICAL, NONLINEAR, AND SOFT MATTER PHYSICS», 2002, 65, Article number: 061910, pp. 1 - 4 [articolo]

Vendruscolo M.; Paci E.; Dobson C.M.; Karplus M., Three key residues form a critical contact network in a protein folding transition state, «NATURE», 2001, 409, pp. 641 - 645 [articolo]

Paci E.; Karplus M., Unfolding proteins by external forces and temperature: The importance of topology and energetics, «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 2000, 97, pp. 6521 - 6526 [articolo]

Paci E.; Karplus M., Forced unfolding of fibronectin type 3 modules: An analysis by biased molecular dynamics simulations, «JOURNAL OF MOLECULAR BIOLOGY», 1999, 288, pp. 441 - 459 [articolo]

Paci E.; Marchi M., Intrinsic compressibility and volume compression in solvated proteins by molecular dynamics simulation at high pressure, «PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA», 1996, 93, pp. 11609 - 11614 [articolo]

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