Foto del docente

Concettina Cappadone

Assistant professor

Department of Pharmacy and Biotechnology

Academic discipline: BIO/10 Biochemistry

Publications

Andreani A.; Burnelli S.; Granaiola M.; Leoni A.; Locatelli A.; Morigi R.; Rambaldi M.; Varoli L.; Calonghi N.; Cappadone C.; Voltattorni M.; Zini M.; Stefanelli C.; Masotti L.; Shoemaker R.H, Antitumor Activity of New Substituted 3-(5-Imidazo[2,1-b]thiazolylmethylene)-2-indolinones and 3-(5-Imidazo[2,1-b]thiadiazolylmethylene)-2-indolinones: Selectivity Against Colon Tumor Cells and Effect on Cell Cycle-Related Events., «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 7508 - 7513 [Scientific article]

C. Mangano; N. Calonghi; M. Naldi; F. Di Giorgio; J. Hysomema; C. Parolin; C. Cappadone; A. Mai; L. Masotti, BIOLOGICAL EFFECTS OF A NEW CLASS I HDAC SELECTIVE INHIBITOR IN HT29 COLON CANCER CELLS., in: 53° national meeting of the italian society of biochemistry and molecular biology (SIB), proceedings and report, FIRENZE, firenze university press, 2008, pp. 2.41 - 2.41 (atti di: 53° national meeting of the italian society of biochemistry and molecular biology (SIB), riciione, italy, 23-26 settembre 2008) [Abstract]

C. Mangano; N. Calonghi; C. Parolin; C. Cappadone; F. Di Giorgio; J. Hysomema; M.L. Bolognesi; C. Melchiorre; L. Masotti, CYTOTOXICITY EVALUATION OF A POLYAMINE-QUINONE LIBRARY CONJUGATES IN HUMAN COLON CARCINOMA CELLS, in: 53° National Meeting of the Italian Society of Biochemistry and Molecular Biology (SIB), proceedings and report, FIRENZE, Firenze, university press, 2008, pp. 2.42 - 2.42 (atti di: 53° National Meeting of the Italian Society of Biochemistry and Molecular Biology (SIB), Riccione, Italy, 23-26 settembre 2008) [Abstract]

C. Parolin; N. Calonghi; C. Cappadone; F. Di Giorgio; J. Hysomema; C. Mangano; V. Andrisano; J. Fiori; L. Masotti., EFFECT OF AN INDOLE-DERIVATIVE IN HUMAN OVARIAN CARCINOMA CELLS., in: 53° national meeting of the italian society of biochemistry and molecular biology (SIB), proceedings and report, FIRENZE, firenze university press, 2008, pp. 2.46 - 2.46 (atti di: 53° national meeting of the italian society of biochemistry and molecular biology (SIB), riccione, italy, 23-26 settembre 2008) [Abstract]

C. Parolin; N. Calonghi; M. Naldi; C. Mangano; F. Di Giorgio; J. Hysomema; C. Cappadone; V. Andrisano; A. Mai; L. Masotti, HISTONE POST-TRANSLATIONAL MODIFICATIONS BY HPLC-ESI-MS AFTER HT29 CELL TREATMENT WITH HDACS INHIBITORS., in: 53° national meeting of the italian society of biochemistry and molecular biology (SIB), proceedings and report, FIRENZE, firenze university press, 2008, pp. 2.47 - 2.47 (atti di: 53° national meeting of the italian society of biochemistry and molecular biology (SIB), riccione, italy, 23-26 settembre 2008) [Abstract]

A. Andreani; S. Burnelli; M. Granaiola; A. Leoni; A. Locatelli; R. Morigi; M. Rambaldi; L. Varoli; N. Calonghi; C. Cappadone; G. Farruggia; M. Zini; C. Stefanelli; L. Masotti; N.S. Radin; R.H. Shoemaker, New Antitumor Imidazo[2,1-b]thiazole Guanylhydrazones and Analogues, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 809 - 816 [Scientific article]

Farruggia G.; Cappadone C.; Calonghi N.; Di Giorgio F.; Mangano C.; Parolin C.; Masotti L., CYTOSTATIC AND CYTOTOXIC EFFECTS OF A NEW SYNTHESIZED GUANYLHYDRAZONE DERIVATIVES IN HUMAN LEUKEMIC CELL LINE HL-60, in: , «ITALIAN JOURNAL OF BIOCHEMISTRY», 2007, 56, pp. 74 - 74 (atti di: SIB 2007: 52° congresso nazionale, Riccione, Italy, September 2007) [Abstract]

R. Morigi; A. Andreani; S. Burnelli; M. Granaiola; A. Leoni; A. Locatelli; M. Rambaldi; L. Varoli; N. Calonghi; C. Cappadone; G. Farruggia; M. Zini; C. Stefanelli; L. Masotti., Substituted (E)-3-(2-chloro-3-indolylmethylene)-1,3-dihydroindol-2-ones as antitumor agents: SARs and study of the mechanism of action, in: Frontiers in CNS and Oncology Medicinal Chemistry, WASHINGTON, ACS-EFMC, 2007, pp. 33 - 34 (atti di: Frontiers in CNS and Oncology Medicinal Chemistry, Siena, 7-9 Ottobre 2007) [Abstract]

Andreani A.; Burnelli S.; Granaiola M.; Leoni A.; Locatelli A.; Morigi R.; Rambaldi M.; Varoli L.; Calonghi N.; Cappadone C.; Farruggia G.; Zini M.; Stefanelli C.; Masotti L., Substituted E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity. Effect on the cell cycle and apoptosis., «JOURNAL OF MEDICINAL CHEMISTRY», 2007, 50, pp. 3167 - 3172 [Scientific article]

Cappadone C.; Calonghi N.; Farruggia G.; Mangano C.; Pagnotta E.; Parolin C.; Masotti L., ANTITUMOR ACTIVITY OF INDOLE-DERIVATIVES IN THE HUMAN OVARIAN CANCER CELL LINE IGROV-1, in: , «ITALIAN JOURNAL OF BIOCHEMISTRY», 2006, 55, pp. 48 - 48 (atti di: SIB 2006: 51° congresso SIB, Riccione, Italy, September 2006) [Abstract]

G.Farruggia; C.Cappadone; N.Calonghi; C. Boga; L.Masotti., CYTOTOXIC EFFECTS OF 4-HYDROXYNONENAL IN HUMAN OSTEOSARCOMA CELLS, in: , «ITALIAN JOURNAL OF BIOCHEMISTRY», 2005, 54, pp. 49 - 49 (atti di: SIB 2005: 50° congresso nazionale, Riccione, Italy, September 2005) [Abstract]

N. CALONGHI; C. CAPPADONE; E. PAGNOTTA; C. BOGA; C. BERTUCCI; J. FIORI; G. TASCO; R. CASADIO; MASOTTI L., Histone deacetylase 1: a target of 9-hydroxystearic acid in the inhbition of cell growth in human colon cancer, «JOURNAL OF LIPID RESEARCH», 2005, 46, pp. 1596 - 1603 [Scientific article]

CALONGHI N.; CAPPADONE C.; PAGNOTTA E.; BOGA C.; BERTUCCI C.; FIORI J.; TRALDI P.; MASOTTI L., 4-hydroxy-2,3 trans-nonenal nuclear concentration inversely correlates with the growth rate of T leukemia cells., «ITALIAN JOURNAL OF BIOCHEMISTRY», 2004, 53, pp. 28 - 33 [Scientific article]

N. CALONGHI; C. CAPPADONE; E. PAGNOTTA; G. FARRUGGIA; F. BUONTEMPO; C. BOGA; G.L. BRUSA; M.A. SANTUCCI; MASOTTI L., 9-Hydroxystearic acid upregulates p21WAF1 in HT29 cancer cells., «BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS», 2004, 314, pp. 138 - 142 [Scientific article]

Pagnotta E.; Calonghi N.; Cappadone C.; Boga C.; Dal Piaz F.; Masotti L., 9-hydroxystearic acid is a histone deacetylase inhibitor, in: CIB, CNB7, PARMA, Graphital, 2004, 7, pp. 157 - 157 [Abstract]