Personal data
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Family name: González Vara y Rodríguez .
First name: Antonio.
Place of birth and date: Avila (Spain), 25th March 1964.
Qualifications
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- Oct 1998-to date: Aggregate Professor. Place:
Faculty of Industrial Chemistry. University of Bologna (Italy).
- Oct 2002-to date: Forward Contract Professor. Place:
Faculty of Sciences. University of Urbino (Italy).
- May 1999-May 2001: Research Assistant Professor. Place:
Center for Process Biotechnology. Technical University of
Denmark.
- Sep 1996-Jul 97: Forward Contract Professor.
Place: Faculty of Sciences. University of Bologna
(Italy).
- Feb 1994: Elected member (corespondent) of the Royal Academy
of Doctors of Spain. Place: Madrid (Spain).
- Sep 1992-Sep 95: Ph.D. in Applied Biocatalysis and Industrial
Fermentations. PhD mark: Summa cum Laude .
Place: Consortium of Universities of Bologna, Ferrara and
Padova (Italy). Title of PhD Thesis : “Produzione di acido
L(+) and D(-) lattico in chemostato. Studio cinetico e modellazione
matematica” (Production of L(+) and D(-) lactic acid in chemostat.
Study of kinetics and mathematic modellation). Scientific
supervisor: Prof. Diego Matteuzzi.
- Jan1988-Jul 91: Ph.D. in Pharmacy. PhD mark: Summa
cum Laude . Place: Royal College of Spain. Bologna
(Italy). Title of PhD Thesis: “Costruzioni di vettori
shuttle derivati da un plasmide nativo di Bacillus
coagulans. Clonaggio in Bacillus subtilis e studio di
stabilità in fermentatore” (Costruction of shuttle vectors derived
from a native plasmid of Bacillus coagulans. Cloning in
Bacillus subtillis and study of stability in fermentor).
Scientific supervisor: Prof. Diego Matteuzzi.
- Jan 1990-Jul 91: Laurea in Farmacia (M.Sc. in Pharmacy).
Final mark: 110/110 e Lode. M.Sc. Award: Premio di
Laurea M. Borsari. Place : University of Bologna
(Italy).
- Sep 1987-Jul 88: Master in Business Administration.
Place: High School of Marketing Studies. Madrid (Spain).
- Sep 1987-Jul 88: Master in Marketing and Management.
Place: High School of Marketing Studies. Madrid (Spain).
- Oct 1982-Jul 88: Licenciatura de grado en Farmacia (M.Sc. in
Pharmacy). Final mark: Grado de Sobresaliente (100/100).
M.Sc. Award: Premio Extraordinario de Licenciatura.
Place: University of Alcalá de Henares (Madrid, Spain).
Title of M.Sc. Thesis: “Influencia de la adición de
antiespumantes en la producción de antifúngicos por Streptomyces
albaduncus en fermentador” (Influence of antifoam addition in
the antifungin production of Streptomyces albaduncus in
fermentor).
Grants
- Jan 1988-Dec 1990: S panish Ph.D. grant from Caja de Ahorros y
Monte de Piedad de Madrid (Spain).
- January 1990-Jul 1991: Spanish Ph.D. grant of The Royal
College of Spain in Bologna (Italy).
- Sep 1992-Sep 1994: Italian Ph.D. grant (Dottorato di Ricerca)
from MURST (Italian Ministry for Universities and Scientific
Research).
- Oct-Dec 1994: Research grant from Consorzio Italiano
Interuniversitario di Biotecnologie (Italian Inter-university
Consortium of Biotechnology).
- Jan-Dec 1995: Research grant from Italian and
Spanish Foreign Ministries.
- May 1999- May 2001: EC-fellow (level 3) within
the EC-framework Biotech-2.
Scientific activity
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Places
- Jul 1987 - Jan 1990: Department of Microbiology and
Parasitology. University of Alcalá de Henares (Madrid, Spain).
- Jan 1990 - Nov 1998: Department of Pharmaceutical
Sciences. University of Bologna (Italy).
- Nov 1988 - October 2012: Department of Industrial
Materials Chemistry. University of Bologna (Italy).
- May 1999 - May 2001: Center for Process Biotechnology.
Technical University of Denmark.
- October 2012 to present: Department of Pharmacy and Biotechnology. University of Bologna (Italy).
Research lines
- Jul 1987 - Dec 1989. Study of a new antifungin compound
produced by Streptomyces albaduncus. Direct risponsable for
optimization of fermentative production, isolation and purification
of active principle.
- Jan 1990 - Jul 1991. 1) Costruction of shuttle vectors derived
from native plasmids of thermophilic strains, cloning of such
vectors in Bacillus subtillis strains and study of
segregational stability during continuous fermentations in
nonselective medium. 2) Optimization of lisine fermentative
production by mutant NUB3621 of the thermophilic strain Bacillus
stearothermophilus.
- Sep 1991 - Sep 1995. 1) Production of L and D lactic acid
stereoisomers by Lactobacillus casei ssp. casei DSM
20011 and Lactobacillus coryniformis ssp. torquens
DSM 2004, in batch and continuous fermentation. Study of
fermentation paramethers, productivity optimization and mathematic
modelling of process. 2) Utilization of NIR spectroscopy in on-line
monitoring and control of fermentation processes, using as model
the lactic acid fermentation.
- Oct 1995 - Jul 1996. Determination of
optimal culture conditions of Bacillus stearothermophilus
NUB 3621, and study of stability of recombinant plasmids during the
continuous culture of such strain in nonselective medium. Study of
continuous fermentation optimization and plasmid stability on
Bacillus stearothermophilus NUB3621.
- Sep 1995 - Sep
1998. Study of plasmids and fermentative features of the
genetically transformable strain Bifidobacterium animalis
P-23. Enhancement of biomass production and stability study of
several cloning vectors in continuous fermentation.
- May 1999 - May
2001. Metabolic Engineering of Glycopeptide Antibiotics:
Technology, Optimization and Production. An application to the
teicoplanin production by Actinoplanes teichomyceticus.
- 2001 – to
date. Genetic engineering of Escherichia coli and
Bacillus subtillis aimed to the construction
of suitable strains useful for the directed evolution of
enzymes.
