Foto del docente

Andrea Tarozzi

Full Professor

Department for Life Quality Studies

Academic discipline: BIO/14 Pharmacology

Publications

Andreev S.; Pantsar T.; Tesch R.; Kahlke N.; El-Gokha A.; Ansideri F.; Gratz L.; Romasco J.; Sita G.; Geibel C.; Lammerhofer M.; Tarozzi A.; Knapp S.; Laufer S.A.; Koch P., Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 1283 - 1301 [Scientific article]

Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Letizia Pruccoli, Nathália Fonseca Nadur, Luciana Luíza de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Luiz Felipe Leomil Coelho, Marcos J. Guimarães, Fernanda M. R. da Silva, Newton Castro, Vanessa Silva Gontijo, Viviana C. T. Rojas, Merelym Ketterym de Oliveira, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Gisele Barbosa, Lídia Moreira Lima, Gabriela Beserra Pinheiro, Letícia Germino Veras, Márcia Renata Mortari, Andrea Tarozzi, Claudio Viegas Jr, Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation, «RSC MEDICINAL CHEMISTRY», 2022, 13, pp. 568 - 584 [Scientific article]

Santini, A.; Pruccoli, L.; Guardigni, M.; De Simone, A.; Spyrakis, F.; Frabetti, F.; Andrisano, V.; Bolognesi, M. L.; Tarozzi, A.; Milelli, A., PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION, in: XXVII National Meeting on Medicinal Chemistry, 2022, pp. 160 - 160 (atti di: XXVII National Meeting on Medicinal Chemistry, Bari, 11-14 settembre 2022) [Poster]

Campos H.M.; da Costa M.; da Silva Moreira L.K.; da Silva Neri H.F.; Branco da Silva C.R.; Pruccoli L.; dos Santos F.C.A.; Costa E.A.; Tarozzi A.; Ghedini P.C., Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies, «TOXICOLOGY», 2022, 465, Article number: 153033 , pp. 1 - 13 [Scientific article]

Sarah Macedo Vaz, Matheus de Freitas Silva, Graziella dos Reis Rosa Franco, Marcos Jorge R. Guimaraes, Fernanda Motta R. da Silva, Newton Gonçalves Castro, Isabella Alvim Guedes, Laurent E. Dardenne, Marina Amaral Alves, Rafael Garrett da Costa, Gabriela Beserra Pinheiro, Letícia Germino Veras, Marcia Renata Mortari, Letizia Pruccoli, Andrea Tarozzi, Claudio ´ Viegas Jr., Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer’s disease, «BIOORGANIC & MEDICINAL CHEMISTRY», 2022, 71, pp. 1 - 11 [Scientific article]

Gigliobianco M.R.; Cortese M.; Peregrina D.V.; Villa C.; Lupidi G.; Pruccoli L.; Angeloni C.; Tarozzi A.; Censi R.; Di Martino P., Development of new extracts of crocus sativus l. By-product from two different italian regions as new potential active ingredient in cosmetic formulations, «COSMETICS», 2021, 8, Article number: 51 , pp. 1 - 18 [Scientific article]Open Access

Martina Fazzina, Letizia Pruccoli, Andrea Tarozzi, Francesca Massenzio, Barbara Monti, Davide Maestri, Matteo Bergonzoni, Flavia Frabetti, Raffaella Casadei, Dysregulation of long non-coding RNAs in neuroinflammation: characterization of LINC00520 and its possible role in Parkinson's disease, in: 2nd International Conference on Neuroprotection by Drugs, Nutraceuticals, and Physical Activity, 2021, pp. 35 - 35 (atti di: 2nd International Conference on Neuroprotection by Drugs, Nutraceuticals, and Physical Activity, Virtual edition, 9-10 dicembre 2021) [Abstract]

Pruccoli L.; Breda C.; Teti G.; Falconi M.; Giorgini F.; Tarozzi A., Esculetin provides neuroprotection against mutant huntingtin-induced toxicity in huntington’s disease models, «PHARMACEUTICALS», 2021, 14, Article number: 1044 , pp. 1 - 16 [Scientific article]Open Access

Censi R.; Peregrina D.V.; Gigliobianco M.R.; Lupidi G.; Angeloni C.; Pruccoli L.; Tarozzi A.; Di Martino P., New antioxidant ingredients from brewery by-products for cosmetic formulations, «COSMETICS», 2021, 8, Article number: 96 , pp. 1 - 18 [Scientific article]Open Access

Vittori L.N.; Romasco J.; Tarozzi A.; Maietta Latessa P., Urinary Markers and Chronic Effect of Physical Exercise, in: Methods in Molecular Biology, 999 RIVERVIEW DR, STE 208, TOTOWA, NJ 07512-1165 USA, Humana Press Inc., 2021, pp. 193 - 200 (METHODS IN MOLECULAR BIOLOGY) [Chapter or essay]

Cindy Juliet Cristancho Ortiz; Caio Miranda Damasio; Letizia Pruccoli; Nathália Fonseca Nadur; Luciana Luiza de Azevedo; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Arthur Eugen Kümmerle; Andrea Tarozzi; Claudio Viegas Jr, Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases, «NEUROCHEMICAL RESEARCH», 2020, 45, pp. 3003 - 3020 [Scientific article]

Matheus de Freitas Silva; Ellen Tardelli Lima; Letizia Pruccoli; Newton G Castro; Marcos Jorge R Guimarães; Fernanda M R da Silva; Nathalia Fonseca Nadur; Luciana Luiz de Azevedo; Arthur Eugen Kümmerle; Isabella Alvim Guedes; Laurent Emmanuel Dardenne; Vanessa Silva Gontijo; Andrea Tarozzi; Claudio Viegas, Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease, «MOLECULES», 2020, 25, Article number: 3165 , pp. 1 - 18 [Scientific article]Open Access

Andreev S.; Pantsar T.; El-gokha A.; Ansideri F.; Kudolo M.; Anton D.B.; Sita G.; Romasco J.; Geibel C.; Lammerhofer M.; Goettert M.I.; Tarozzi A.; Laufer S.A.; Koch P., Discovery and evaluation of enantiopure 9H-pyrimido[4,5‐b]indoles as nanomolar GSK‐3β inhibitors with improved metabolic stability, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2020, 21, Article number: 7823 , pp. 1 - 41 [Scientific article]Open Access

Pruccoli, L; Morroni, F; Sita, G; Hrelia, P; Tarozzi, A, Esculetin as a Bifunctional Antioxidant Prevents and Counteracts the Oxidative Stress and Neuronal Death Induced by Amyloid Protein in SH-SY5Y Cells, «ANTIOXIDANTS», 2020, 9, Article number: 551 , pp. 1 - 16 [Scientific article]Open Access

Rita Maria Concetta Di Martino; Letizia Pruccoli; Alessandra Bisi; Silvia Gobbi; Angela Rampa; Ana Martinez; Concepción Pérez; Loreto Martinez-Gonzalez; Maria Paglione; Elia Di Schiavi; Francesca Seghetti; Andrea Tarozzi; Federica Belluti, Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease, «ACS CHEMICAL NEUROSCIENCE», 2020, 11, pp. 2728 - 2740 [Scientific article]