Mesquita Campos, Hericles; Mota Pereira, Robbert; Yasmin de Oliveira Ferreira, Pamela; Uchenna, Nkaa; Rio Branco da Silva, Cínthia; Pruccoli, Letizia; Sanz, German; Ferreira Rodrigues, Marcella; Gontijo Vaz, Boniek; Gonçalves Rivello, Barbara; Luís Batista da Rocha, Andre; Silva de Carvalho, Flavio; de Almeida Ribeiro Oliveira, Gerlon; Morais Liao, Luciano; de Castro Georg, Raphaela; Alves Leite, Jacqueline; Cristina Alcantara dos Santos, Fernanda; Alves Costa, Elson; Menegatti, Ricardo; Tarozzi, Andrea; Cesar Ghedini, Paulo, A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3- nitropropionic acid in in vitro and in vivo models, «CHEMICO-BIOLOGICAL INTERACTIONS», 2024, 395, Article number: 111026 , pp. 1 - 10 [Scientific article]
Pruccoli, Letizia; Nicolini, Benedetta; Lianza, Mariacaterina; Teti, Gabriella; Falconi, Mirella; Tarozzi, Andrea; Antognoni, Fabiana, Antioxidant and Anti-Melanogenesis Effects of Teucrium chamaedrys L. Cell Suspension Extract and Its Main Phenylethanoid Glycoside in B16-F10 Cells, «PLANTS», 2024, 13, Article number: 808 , pp. 1 - 9 [Scientific article]Open Access
Pruccoli, Letizia; Balducci, Martina; Pagliarani, Barbara; Tarozzi, Andrea, Antioxidant and Neuroprotective Effects of Fucoxanthin and Its Metabolite Fucoxanthinol: A Comparative In Vitro Study, «CURRENT ISSUES IN MOLECULAR BIOLOGY», 2024, 46, pp. 5984 - 5998 [Scientific article]Open Access
Victor Ifeanyi Okoh, Hericles Mesquita Campos, Pâmela Yasmin de Oliveira Ferreira, Robbert Mota Pereira, Yohanny Souza Silva, Evilanna Lima Arruda, Barbara Pagliarani, Gerlon de Almeida Ribeiro Oliveira, Luciano Morais Lião, Gabriel Franco Dos Santos, Boniek Gontijo Vaz, José Ricardo Sabino, Fernanda Cristina Alcantara Dos Santos, Elson Alves Costa, Andrea Tarozzi, Ricardo Menegatti, Paulo César Ghedini, Chrysin bonded to β-d-glucose tetraacetate enhances its protective effects against the neurotoxicity induced by aluminum in Swiss mice, «JOURNAL OF PHARMACY AND PHARMACOLOGY», 2024, 76, pp. 368 - 380 [Scientific article]
Santini A.; Tassinari E.; Poeta E.; Loi M.; Ciani E.; Trazzi S.; Piccarducci R.; Daniele S.; Martini C.; Pagliarani B.; Tarozzi A.; Bersani M.; Spyrakis F.; Danková D.; Olsen C.A.; Soldati R.; Tumiatti V.; Montanari S.; De Simone A.; Milelli A., First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease, «ACS CHEMICAL NEUROSCIENCE», 2024, 15, pp. 2099 - 2111 [Scientific article]
de Freitas Silva, Matheus; Juliet Cristancho Ortiz, Cindy; Ferreira Coelho, Letícia; Pruccoli, Letizia; Pagliarani, Barbara; Pisani, Leonardo; Catto, Marco; Poli, Giulio; Tuccinardi, Tiziano; Cardoso Vilela, Fabiana; Giusti-Paiva, Alexandre; Amaral Alves, Marina; Ribeiro de Souza, Hygor M.; Tarozzi, Andrea; Silva Gontijo, Vanessa; Jr., Claudio Viegas, Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson’s disease, «BIOORGANIC CHEMISTRY», 2024, 150, Article number: 107587 , pp. 1 - 18 [Scientific article]
Balducci M.; Pruccoli L.; Tarozzi A., Heat stress as a potential risk factor for vitamin D deficiency, «MEDICAL HYPOTHESES», 2023, 176, Article number: 111085 , pp. 1 - 3 [Scientific article]Open Access
Tarozzi A.; Angeloni C., Neuroprotection by Drugs, Nutraceuticals and Physical Activity, «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES», 2023, 24, Article number: 3176 , pp. 1 - 7 [Scientific article]Open Access
Guardigni M.; Pruccoli L.; Santini A.; Simone A.D.; Bersani M.; Spyrakis F.; Frabetti F.; Uliassi E.; Andrisano V.; Pagliarani B.; Fernández-Gómez P.; Palomo V.; Bolognesi M.L.; Tarozzi A.; Milelli A., PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease, «ACS CHEMICAL NEUROSCIENCE», 2023, 14, pp. 1963 - 1970 [Scientific article]Open Access
De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena, Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2023, 252, Article number: 115297 , pp. 1 - 15 [Scientific article]Open Access
Andreev S.; Pantsar T.; Tesch R.; Kahlke N.; El-Gokha A.; Ansideri F.; Gratz L.; Romasco J.; Sita G.; Geibel C.; Lammerhofer M.; Tarozzi A.; Knapp S.; Laufer S.A.; Koch P., Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors, «JOURNAL OF MEDICINAL CHEMISTRY», 2022, 65, pp. 1283 - 1301 [Scientific article]Open Access
Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Letizia Pruccoli, Nathália Fonseca Nadur, Luciana Luíza de Azevedo, Arthur Eugen Kümmerle, Isabella Alvim Guedes, Laurent Emmanuel Dardenne, Luiz Felipe Leomil Coelho, Marcos J. Guimarães, Fernanda M. R. da Silva, Newton Castro, Vanessa Silva Gontijo, Viviana C. T. Rojas, Merelym Ketterym de Oliveira, Fabiana Cardoso Vilela, Alexandre Giusti-Paiva, Gisele Barbosa, Lídia Moreira Lima, Gabriela Beserra Pinheiro, Letícia Germino Veras, Márcia Renata Mortari, Andrea Tarozzi, Claudio Viegas Jr, Design, synthesis, and biological evaluation of new thalidomide–donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation, «RSC MEDICINAL CHEMISTRY», 2022, 13, pp. 568 - 584 [Scientific article]Open Access
Santini, A.; Pruccoli, L.; Guardigni, M.; De Simone, A.; Spyrakis, F.; Frabetti, F.; Andrisano, V.; Bolognesi, M. L.; Tarozzi, A.; Milelli, A., PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION, in: XXVII National Meeting on Medicinal Chemistry, 2022, pp. 160 - 160 (atti di: XXVII National Meeting on Medicinal Chemistry, Bari, 11-14 settembre 2022) [Poster]
Campos H.M.; da Costa M.; da Silva Moreira L.K.; da Silva Neri H.F.; Branco da Silva C.R.; Pruccoli L.; dos Santos F.C.A.; Costa E.A.; Tarozzi A.; Ghedini P.C., Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies, «TOXICOLOGY», 2022, 465, Article number: 153033 , pp. 1 - 13 [Scientific article]Open Access
Sarah Macedo Vaz, Matheus de Freitas Silva, Graziella dos Reis Rosa Franco, Marcos Jorge R. Guimaraes, Fernanda Motta R. da Silva, Newton Gonçalves Castro, Isabella Alvim Guedes, Laurent E. Dardenne, Marina Amaral Alves, Rafael Garrett da Costa, Gabriela Beserra Pinheiro, Letícia Germino Veras, Marcia Renata Mortari, Letizia Pruccoli, Andrea Tarozzi, Claudio ´ Viegas Jr., Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids
designed as novel multifunctional drug candidates for Alzheimer’s disease, «BIOORGANIC & MEDICINAL CHEMISTRY», 2022, 71, Article number: 116952 , pp. 1 - 11 [Scientific article]Open Access