The following list summarizes the most important steps of Prof.
Andrea Cavalli's educational and professional career:
- MSc in Medicinal Chemistry - University of Bologna
- PhD in Pharmaceutical Sciences - University of Bologna
- Postdoctoral Fellow in Comput. Biophysics - SISSA/ISAS of
- Visiting Scientist - ETH Zurich - 2001, 2002
- Assistant Professor at the University of Bologna
- Associate Professor at the University of Bologna
- Head of CompuNet of the Italian Institute of Technology of
- Full Professor in Medicinal Chemistry at the University of
Since the beginning of his PhD thesis, Dr. Cavalli has focused
on drug discovery projects. Initially, he worked in the field of
anti-cancer drug design, investigating the aromatase and cytochrome
P450 17 structures as molecular targets. This work was performed in
collaboration with other research groups in Italy and in Germany.
During his postdoctoral fellowship at the International School for
Advanced Studies (SISSA/ISAS) of Trieste, he augmented his skills
in structure-based drug design. He applied these skills to search
for new drug candidates against Alzheimer's disease (see Cavalli
A., et al. Angew. Chem. Int. Ed. Engl. 2007,
46, 3689 and Cavalli et al. J. Med. Chem.
2008, 51, 347), after having become Assistant
Professor at the University of Bologna. Since 2002, he has also
been devoted to the development of both ligand- and structure-based
in silico tools that are able to predict the interactions between
drugs and the hERG potassium channel. The latter is a
well-recognized anti-target responsible for the withdrawal from the
market of several drugs in recent years. Due to the
interdisciplinary character of drug discovery projects, he has
worked with other groups at his department and industrial partners,
gaining important experience in cooperating with and managing
external collaborations. Having spent almost a year as visiting
scientist at the ETH-Zurich in Switzerland, he gained international
experience and further developed his scientific network in the drug
discovery field. Since 2006, Prof. Cavalli has been independently
initiating research projects and leading a drug design and
discovery team. He is currently the leader of the Computational
Chemistry and Structural Biophysics group of the Department of Drug
Discovery and Development of the Italian Institute of Technology of
Genoa, where he also is coordinator of a new PhD program in Drug
Prof. Cavalli is the author of over 190 publications in
international journals with a high impact factor (Nature
Commun., Nat. Neurosci., Chem. Rev., Acc. Chem.
Res., Angew. Chem. Int. Ed. Engl., Proc. Natl. Acad. Sci.
USA, Med. Res. Rev., J. Am. Chem. Soc., Bioinformatics, J.
Biol. Chem., J. Med. Chem., Chem.-Eur. J., Chem. Commun.,
Proteins, etc.) and has delivered more than
70 invited lectures and seminars. In 2001, he organized an
International Workshop at the SISSA/ISAS of Trieste. In 2001, he
was invited to be Guest Editor of a special issue of the journal
QSAR, which was dedicated to the ‘Density Functional
Theory': the issue was published in July 2002 (QSAR,
21, 93-236). Since 2007, he has been the Managing Editor of
the Frontiers In Biosciences journal, and recently he has
been invited to join the Editorial Board for Bentham's The Open
Applied Informatics Journal. Prof. Cavalli is also
member of the Editorial Board of Med. Chem.
Commun., World Journal of Translational Medicine,
World Journal of Neuroscience, etc. In 2003, he was
awarded the ‘Farmindustria Prize for Pharmaceutical Research',
which is dedicated to scientists younger than 40 years old. Since
2003, he has been the advisor for several diploma and PhD theses.
Since 2007, he has been a member of the Faculty for the PhD course
in Physics and Chemistry of Biological Systems (Curriculum in Drug
Discovery) at the International School for Advanced Studies of
Trieste. He is a peer reviewer for Human Frontier Science Program
(HFSP), for the American Alzheimer's Association, for
the Austrian Science Fund, for the Swiss National Science
Foundation, for the Israel Science Foundation, for the PRIN
Projects (MiUR-Italy), and for the Committee for Evaluation of
Research (CIVR-MiUR), a body nominated by the Italian government to
promote research evaluation activities. Furthermore, he is a
referee for the following international journals: Angew. Chem.
Int. Ed. Engl.; J. Am. Chem. Soc.; J. Med. Chem.; Chem.
Commun.; Proteins; Br. J. Pharmacol.; Mol. Pharmacol.; etc. He
is Academic Editor of PLoS ONE and a member of the Scientific
Committee of the supercomputer center CINECA.
You may find the list of my papers