Name
Andrea Bottoni
Position
Professor of Organic Chemistry- at present Alma Mater Honorary Professor
Born
Jan 27, 1950
Nationality
Italian
Address
Dipartimento di Chimica “G. Ciamician”, Università di Bologna,
via F. Selmi 2, 40126 Bologna, Italy, Tel +39 051 209 94 77 or +39
348 312 01 43; Fax +39 051 209 94 56
E-mail
andrea.bottoni@.unibo.it
Homepage
www.ciam.unibo.it
Academic qualifications
and
research career
1976 Laurea in Chimica (110/110 summa cum laude)
1977-1982 post-doctoral period granted by the Italian National
Research Council at the University of Bologna
1982-1992 Lecturer (Ricercatore), University of Bologna
1983-1984 Research Associate, King's College, London (granted by
Accademia dei Lincei and Royal Society of Chemistry).
1992-2001 Associate Professor of Organic Chemistry, Department
of Chemistry “G. Ciamician”, University of Bologna
2001-2019 Full Professor of Organic Chemistry, Department of
Chemistry “G. Ciamician”, University of Bologna
2004-2010 Head of the Department of Chemistry "G.Ciamician",
Univeristy of Bologna
2008-2012 Member of the Academic Senate of the University
of Bologna
2012-2018 Dean of the School of Science
Publications
More than 160 papers in internationally refereed journals of high impact factor such
as: J. Am. Chem. Soc. J. Phys. Chem. J. Org. Chem., Proteins.
Research
1. Implementation of new “software” suitable to describe large
molecular systems, in particular enzyme or conventional organic and
organometallic reactions where a bulk of solvent molecules is
explicitly described. This “software” is based on a hybrid
quantum-mechanical(QM)/molecular mechanics (MM) approach.
2. Theoretical Study and Computational Modeling of Organic and
Organometallic Reactions.
The aim of these studies is: (a) To determine the mechanism of
synthetically important reactions in both industry and academic
laboratories. (b) To recognize the “active species” involved in
metal-catalyzed or metal-mediated processes. (c) To understand the
specific role played by the metal. These studies are performed by
means of QM (DFT, MSCSCF, CI, Moller-Plesset, Coupled Cluster) and
hybrid QM/MM methods.
3. Computational Modeling of Biochemical Reactions.
The mechanism of important biological reactions is investigated
by means of QM, MM and QM/MM methods. In particular, reactions
involving enzymes and metal-enzymes are examined. Our aim is to
define a strategy that allows to obtain reliable model-systems to
simulate the behavior of important biological processes. This
strategy is based either on a conventional investigation of the
potential energy surface or molecular dynamics techniques.
4. Computational study of non-conventional catalysis: catalysis using oriented external electric field applied to the reacting system and carbocatalysis using nanastructures such as nanotubes, graphene, fullerenes. For this class of problems the use of hybrid QM/MM methods is particularly important.
Collaborations
Strong collaborations are active with experimental and
theoretical groups such as: Juan Novoa (University of Barcellona),
Ernst Anders (University of Jena), Francesco Naso, Cosimo Cardellicchio (Università di
Bari), Mario Orena (Università di Ancona), Gerard Cahiez (Chimie ParisTech (ENSCP)).
