Foto del docente

Andrea Bottoni

Alma Mater Honorary Professor

Alma Mater Studiorum - Università di Bologna

Adjunct professor

Department of Chemistry "Giacomo Ciamician"

Curriculum vitae

Name

Andrea Bottoni

Position

Professor of Organic Chemistry- at present Alma Mater Honorary Professor

Born

Jan 27, 1950

Nationality

Italian

Address

Dipartimento di Chimica “G. Ciamician”, Università di Bologna, via F. Selmi 2, 40126 Bologna, Italy, Tel +39 051 209 94 77 or +39 348 312 01 43; Fax +39 051 209 94 56

E-mail

andrea.bottoni@.unibo.it

Homepage

www.ciam.unibo.it

Academic qualifications

and

research career

1976 Laurea in Chimica (110/110 summa cum laude)

1977-1982 post-doctoral period granted by the Italian National Research Council at the University of Bologna

1982-1992 Lecturer (Ricercatore), University of Bologna

1983-1984 Research Associate, King's College, London (granted by Accademia dei Lincei and Royal Society of Chemistry).

1992-2001 Associate Professor of Organic Chemistry, Department of Chemistry “G. Ciamician”, University of Bologna

2001-2019 Full Professor of Organic Chemistry, Department of Chemistry “G. Ciamician”, University of Bologna

2004-2010 Head of the Department of Chemistry "G.Ciamician", Univeristy of Bologna

2008-2012  Member of the Academic Senate of the University of Bologna

2012-2018 Dean of the School of Science

Publications

More than 160 papers in internationally refereed journals of high impact factor such as: J. Am. Chem. Soc. J. Phys. Chem. J. Org. Chem., Proteins.

Research

1. Implementation of new “software” suitable to describe large molecular systems, in particular enzyme or conventional organic and organometallic reactions where a bulk of solvent molecules is explicitly described. This “software” is based on a hybrid quantum-mechanical(QM)/molecular mechanics (MM) approach.

2. Theoretical Study and Computational Modeling of Organic and Organometallic Reactions.

The aim of these studies is: (a) To determine the mechanism of synthetically important reactions in both industry and academic laboratories. (b) To recognize the “active species” involved in metal-catalyzed or metal-mediated processes. (c) To understand the specific role played by the metal. These studies are performed by means of QM (DFT, MSCSCF, CI, Moller-Plesset, Coupled Cluster) and hybrid QM/MM methods.

3. Computational Modeling of Biochemical Reactions.

The mechanism of important biological reactions is investigated by means of QM, MM and QM/MM methods. In particular, reactions involving enzymes and metal-enzymes are examined. Our aim is to define a strategy that allows to obtain reliable model-systems to simulate the behavior of important biological processes. This strategy is based either on a conventional investigation of the potential energy surface or molecular dynamics techniques.

4. Computational study of non-conventional catalysis: catalysis using oriented external electric field applied to the reacting system and carbocatalysis using nanastructures such as nanotubes, graphene, fullerenes. For this class of problems the use of hybrid QM/MM methods is particularly important.

Collaborations

Strong collaborations are active with experimental and theoretical groups such as: Juan Novoa (University of Barcellona), Ernst Anders (University of Jena), Francesco Naso, Cosimo Cardellicchio (Università di Bari), Mario Orena (Università di Ancona), Gerard Cahiez (Chimie ParisTech (ENSCP)).