Foto del docente

Alessandra Stefan

Assistant professor

Department of Pharmacy and Biotechnology

Academic discipline: CHEM-07/C Chemistry and Biotechnology of Fermentation

Publications

Stefan, Alessandra; Gentilucci, Luca; Liao, Hang; Hochkoeppler, Alejandro, The assembly of monomeric human L-lactate dehydrogenase into catalytically active homotetramer is hindered by long-chain dicarboxylates, «BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS», 2026, 812, Article number: 153542 , pp. 1 - 7 [Scientific article]Open Access

Stefan, A.; Hochkoeppler, A., Not only an inhibitor: Trehalose enhances the catalytic action exerted on oxaloacetate by rabbit lactate dehydrogenase, «PROTEIN SCIENCE», 2025, 34, pp. 1 - 17 [Scientific article]Open Access

Stefan, A.; Hochkoeppler, A., The catalytic action of enzymes exposed to charged substrates outperforms the activity exerted on their neutral counterparts, «BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS», 2025, 751, pp. 1 - 6 [Scientific article]Open Access

Stefan, Alessandra; Gentilucci, Luca; Ruffolo, Francesca; Rossi, Valentina; Sordi, Sofia; He, Tingting; di Stefano, Giuseppina; Santino, Federica; Brigotti, Maurizio; Scotti, Claudia; Iamele, Luisa; de Jonge, Hugo; Piaz, Fabrizio Dal; Santarcangelo, Danilo Rocco; Hochkoeppler, Alejandro, Peptides inhibiting the assembly of monomeric human l‐lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells, «PROTEIN SCIENCE», 2024, 33, Article number: e5161 , pp. 1 - 26 [Scientific article]Open Access

Stefan, A.; Mucchi, A.; Hochkoeppler, A., The catalytic action of human D-lactate dehydrogenase is severely inhibited by oxalate and is impaired by mutations triggering D-lactate acidosis, «ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS», 2024, 754, Article number: 109932 , pp. 1 - 15 [Scientific article]Open Access

Kovermann M.; Stefan A.; Palazzetti C.; Immler F.; Dal Piaz F.; Bernardi L.; Cimone V.; Bellone M.L.; Hochkoeppler A., The Mycobacterium tuberculosis protein tyrosine phosphatase MptpA features a pH dependent activity overlapping the bacterium sensitivity to acidic conditions, «BIOCHIMIE», 2023, 213, pp. 66 - 81 [Scientific article]Open Access

Alessandra Stefan; Chiara Palazzetti; Alejandro Hochkoeppler, Tyrosine inhibits the Mycobacterium tuberculosis protein tyrosine phosphatase MptpA, «Journal of Proteins and Proteomics», 2023, 14, pp. 175 - 180 [Scientific article]Open Access

Lapenna A.; Stefan A.; Hochkoeppler A., ASFV DNA polymerase extends recessed DNAs with catalytic efficiencies outperforming those exerted on gapped DNA substrates, «BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS», 2021, 534, pp. 526 - 532 [Scientific article]

Monti N.; Zacchini S.; Massi M.; Hochkoeppler A.; Giorgini L.; Fiorini V.; Stefan A.; Stagni S., Antibacterial activity of a new class of tris homoleptic Ru (II)-complexes with alkyl-tetrazoles as diimine-type ligands, «APPLIED ORGANOMETALLIC CHEMISTRY», 2020, 34, Article number: e5806 , pp. 1 - 14 [Scientific article]Open Access

Stefan A.; Gentilucci L.; Piaz F.D.; D'Alessio F.; Santino F.; Hochkoeppler A., Purification from Deinococcus radiodurans of a 66 kDa ABC transporter acting on peptides containing at least 3 amino acids, «BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS», 2020, 529, pp. 869 - 875 [Scientific article]Open Access

Stefan A.; Dal Piaz F.; Girella A.; Hochkoeppler A., Substrate Activation of the Low-Molecular Weight Protein Tyrosine Phosphatase from Mycobacterium tuberculosis, «BIOCHEMISTRY», 2020, 59, pp. 1137 - 1148 [Scientific article]Open Access

Stout M.J.; Stefan A.; Skelton B.W.; Sobolev A.N.; Massi M.; Hochkoeppler A.; Stagni S.; Simpson P.V., Synthesis and Photochemical Properties of Manganese(I) Tricarbonyl Diimine Complexes Bound to Tetrazolato Ligands, «EUROPEAN JOURNAL OF INORGANIC CHEMISTRY», 2020, 2020, pp. 292 - 298 [Scientific article]Open Access

Zanoni I.; Blosi M.; Fiorini V.; Crosera M.; Ortelli S.; Stagni S.; Stefan A.; Psilodimitrakopoulos S.; Stratakis E.; Filon F.L.; Costa A.L., Use of cotton textiles coated by ir(III) tetrazole complexes within ceramic silica nanophases for photo-induced self-marker and antibacterial application, «NANOMATERIALS», 2020, 10, Article number: 1020 , pp. 1 - 17 [Scientific article]Open Access

Kovermann M.; Stefan A.; Castaldo A.; Caramia S.; Hochkoeppler A., Structural and catalytic insights into HoLaMa, a derivative of Klenow DNA polymerase lacking the proofreading domain, «PLOS ONE», 2019, 14, Article number: e0215411 , pp. e0215411 - e0215411 [Scientific article]Open Access

Fiorini, Valentina*; Bergamini, Linda; Monti, Nicola; Zacchini, Stefano; Plush, Sally E.; Massi, Massimiliano; Hochkoeppler, Alejandro; Stefan, Alessandra; Stagni, Stefano, Luminescent protein staining with Re(i) tetrazolato complexes, «DALTON TRANSACTIONS», 2018, 47, pp. 9400 - 9410 [Scientific article]Open Access

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