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Alessandra Bisi

Professoressa associata confermata

Dipartimento di Farmacia e Biotecnologie

Settore scientifico disciplinare: CHIM/08 CHIMICA FARMACEUTICA

Pubblicazioni

S. Rizzo; A. Tarozzi; M. Bartolini; G. Da Costa; A. Bisi; S. Gobbi; F. Belluti; A. Ligresti; M. Allarà; J-P. Monti; V. Andrisano; V. Di Marzo; P. Hrelia; A. Rampa, 2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2012, 58, pp. 519 - 532 [articolo]

F. Belluti; M. Bartolini; G. Bottegoni; A. Bisi; A. Cavalli; V. Andrisano; A. Rampa, Benzophenone-based derivatives: A novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2011, 46, pp. 1682 - 1693 [articolo]

A. Rampa; F. Belluti; S. Gobbi; A. Bisi, Hybrid-Based Multi-Target Ligands for the Treatment of Alzheimer's Disease, «CURRENT TOPICS IN MEDICINAL CHEMISTRY», 2011, 11, pp. 2716 - 2730 [articolo]

S. Rizzo; A. Bisi; M. Bartolini; F. Mancini; F. Belluti; S. Gobbi; V. Andrisano; A. Rampa, Multi-target strategy to address Alzheimer’s disease: Design, synthesis and biological evaluation of new tacrine-based dimers, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2011, 46, pp. 4336 - 4343 [articolo]

Gobbi S.; Zimmer C.; Belluti F.; Rampa A.; Hartmann R.W.; Recanatini M.; Bisi A., Novel highly potent and selective nonsteroidal aromatase inhibitors: synthesis, biological evaluation and structure-activity relationships investigation, «JOURNAL OF MEDICINAL CHEMISTRY», 2010, 53, pp. 5347 - 5351 [articolo]

S. Bova; S. Saponara; A. Rampa; S. Gobbi; L. Cima; F. Fusi; G. Sgaragli; M. Cavalli; C. de los Rios; J. Striessnig; A. Bisi, Anthracene Based Compounds as New L-type Ca2+ Channel Blockers: Design, Synthesis, and Full Biological Profile, «JOURNAL OF MEDICINAL CHEMISTRY», 2009, 52, pp. 1259 - 1262 [articolo]

F. Belluti; L. Piazzi; A. Bisi; S. Gobbi; M. Bartolini; A. Cavalli; P. Valenti; A. Rampa, Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors, «EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY», 2009, 44, pp. 1341 - 1348 [articolo]

S. Rizzo; A. Cavalli; L. Ceccarini; M. Bartolini; F. Belluti; A. Bisi; V. Andrisano; M. Recanatini; A. Rampa, Structure-Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine, «CHEMMEDCHEM», 2009, 4, pp. 670 - 679 [articolo]

S. Rizzo; C. Riviere; L. Piazzi; A. Bisi; S. Gobbi; M. Bartolini; V. Andrisano; F. Morroni; A. Tarozzi; J. P. Monti; A. Rampa, Benzofuran-Based Hybrid Compounds for the Inhibition of Cholinesterase Activity, Abeta Amyloid Aggregation, and Abeta Neurotoxicity, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 2883 - 2886 [articolo]

Gobbi S.; Cavalli A.; Bisi A.; Recanatini M., From nonsteroidal aromatase inhibitors to multifunctional drug candidates: classic and innovative strategies for the treatment of breast cancer., «CURRENT TOPICS IN MEDICINAL CHEMISTRY», 2008, 8, pp. 869 - 887 [articolo]

A. Bisi; M. Meli; S. Gobbi; A. Rampa; M. Tolomeo; L. Dusonchet, Multidrug resistance reverting activity and antitumor profile of new phenothiazine derivatives, «BIOORGANIC & MEDICINAL CHEMISTRY», 2008, 16, pp. 6474 - 6482 [articolo]

S. Lucas; R. Heim; M. Negri; I. Antes; C. Ries; K. E. Schewe; A. Bisi; S. Gobbi; R; W. Hartmann, Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach, «JOURNAL OF MEDICINAL CHEMISTRY», 2008, 51, pp. 6138 - 6149 [articolo]

Barbera M.; Caputo A.; Zampiron A.; Gobbi S.; Rampa A.; Bisi A.; Carrara M., The ability of coumarin-, flavanon- and flavonol-analogues of flavone acetic acid to stimulate human monocytes., «ONCOLOGY REPORTS», 2008, 19, pp. 187 - 196 [articolo]

L. Piazzi; F. Belluti; A. Bisi; S. Gobbi; S. Rizzo; M. Bartolini; V. Andrisano; M. Recanatini; A. Rampa, CHOLINESTERASE INHIBITORS: SAR AND ENZYME INHIBITORY ACTIVITY OF 3-[omega-(BENZYLMETHYLAMINO)ALKOXY]XANTHEN-9-ONES, «BIOORGANIC & MEDICINAL CHEMISTRY», 2007, 15, pp. 575 - 585 [articolo]

Piazzi L.; Cavalli A.; Belluti F.; Bisi A.; Gobbi S.; Rizzo S.; Bartolini M.; Andrisano V.; Recanatini M.; Rampa A., Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives., «JOURNAL OF MEDICINAL CHEMISTRY», 2007, 50, pp. 4250 - 4254 [articolo]